Session1-lec 2 Flashcards
What are the cytoplasmic changes in necrosis
1-more eiosinophilia
*lose of RNA
*binding eiosin to denatuarating protein
2-more homogenous apperance
*lose of glycogen
3-vacuoles in cytoplasm
*enzymes digest organelles
What are nuclear morphological change in necrosis
1-pyknosis (fading of basophilia )
2-karyolysis (shrinking nucleus,increase basophilia,DNA become solid)
3-kyrorrehxis (fragmentation of nucleus)
Morphology of necrosis include
1-discontinuities of plasma membrane
2-dilated mitochondria-increased amorphous densities
3-intracytoplasmic myelin figuers
4-oismiophilic morphous debris
5-aggregetes of fluffy denaturated protein
Types of necrosis
1-coagulative necrosis
2-liquifactive necrosis
3-fat necrosis
4-caseation necrosis
5-gangrenous necrosis
In coagulative necrosis the fine details in the cell _______
Lost
Sudden ischemia in coagulative necrosis in organ cause denaturation in both protein and enzymed (T/F)
T
In coagulative necrosis the cytoplasm stains homogeneous deeply basophilic (T/F)
F
Eiosinoplilic
Affected tissue in coagulative necrosis maintain _______
Solid consistency
Causes of liquifactive necrosis
1-focal bacterial infection
2-fungus infection
3-hypoxia in (CNS)
End result of liquifactive necrosis
Liquid viscous mass
The material of dead cell in liquifactive mecrosis somotimes looks creamy yellow?
Beacuse the presence of dead WBC (PUS) because the process intiated by acute inflamation
Gengenous necrosis is combination of _____ and _____
Coagulative and liquifactive necrosis
Gengenous necrosis found in 2 types what are they
Dry
Wet
Caseous mean
Caseous mean
