Session Two

Question 1

Infection

Answer 1

colonization of the body by a bacterium capable of causing a disease

Question 2

Disease

Answer 2

infection that produces symptoms

Question 3

colonization

Answer 3

bacterium occupies and multiplies in a particular area of the body

Question 4

Asymptomatic carrier

Answer 4

an infected person who does not have symptoms

Question 5

Symptoms

Answer 5

effects of bacterial infection apparent in an infected individual

Question 6

Virulence

Answer 6

ability of bacterium to cause disease

Question 7

Virulence factor

Answer 7

bacterial product or strategy that contributes to virulence or pathogenicity

Question 8

Opportunists

Answer 8

bacteria that normally do not cause disease in healthy people but can cause disease in people that immunocomprised

Question 9

Pathogen

Answer 9

an organism with a reputation of causing infectious disease

Question 10

Describe some models associated with measuring infectivity and virulence and state the value and limitations of each:

Answer 10

a) Survival curve analysis and biophotonic imaging
b) measuring ID50 and LD50 in animal models
c) competition assays with wt and mutant organisms