Antibiotics Flashcards
1
Q
What are the five main targets for antibiotic action
A
- Cell wall synthesis
- Protein synthesis
- Nucleic acid synthesis
- Competitors of metabolic pathway
- Cell membrane
2
Q
List examples of inhibitors of cell wall synthesis
A
- beta lactam antibiotics
- glycopeptides
- bacitracin
- phosphonomycin
3
Q
What are some examples of Beta Lactam antibiotics
A
- penicillins
- cephalosporins
- carbapenems
- monobactams
4
Q
Describe the mechanism of action of beta lactam antibiotics:
A
1) structure resembles D-Ala-D-Ala, mirrors
2) acts as irreversible competitor for PBP
Blocks formation of peptide crosslinks of PG
