Session 9 - Lecture 2 - Headache Flashcards

1
Q

1 - Headache

A

Headache

“Headache is probably the most common neurological problem.”

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2
Q

2 - Contents

A
Contents
• Case
• History
• Examination
• Types of headache
• Red Flags
https://www.fotosearch.com/CSP992/k13365758/

“So, we’re going to talk you through hx, examination, diff types of headaches, focusing primarily on primary headaches (more benign) – talk through red flags, use a case history to discuss these.”

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3
Q

3 - Patient Case
Rachel, a 24 year old female comes to you, as her GP, with headaches.

What are you going to do?

A

Patient Case
Rachel, a 24 year old female comes to you, as her GP, with headaches.

  • What are you going to do?
  • First, always history and examination to get DIFFERENTIAL DIAGNOSIS

“First question always what are you going to do? As always, history and examination for DDx and then work out what you have to do next.”

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4
Q

4 - Differential Of Headaches

[speech]

A

Differential Of Headaches

ACUTE
• VASCULAR: Haemorrhage: SAH, intracranial bleed, sinus venous thrombosis
• INFECTION/INFLAMMATION: Meningitis, Encephalitis, Abscess
• OPHTHALMIC: Acute glaucoma
• SITUATIONAL: cough, exertion, coitus

CHRONIC
• MIGRAINE
• CLUSTER HEADACHES
• DRUGS: Analgesics, Caffeine, Vasodilators (i.e. side effects of other drugs)
• TENSION HEADACHES
• NEURALGIA (TRIGEMINAL)
• ICP ↑: tumours
• GIANT CELL ARTERITIS
• SYSTEMIC: HTN (pheochromocytoma, pre- eclampsia)

“So DDx for headaches can be split into Acute and chronic- acute: vascular, e.g. subarachnoid haemorrhages; infections like meningitis; Opthalmic thinking about acute closed-angle glaucoma; situational, most common is post-coital headache. And Chronic headache thinking about more primary benign headaches like migraines, cluster headaches, tension headaches and trigeminal neuralgia, medication-overuse headaches, raised ICP, giant cell arteritis and systemic causes of headaches – things that can caused raised BP, things like pheochromocytoma and pre-eclampsia in pregnant ladies.”

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5
Q

5 - Primary vs Secondary Headache

A

Primary vs Secondary Headache

Primary
• Due to the headache condition itself, not due to another cause
• E.g. migraine, tension, cluster

Secondary
• Headache that is present because of another condition
• E.g. headache in meningitis/sinusitis/SAH
• Medication overuse is in this category

“So, you can also categorise headaches into primary & secondary headaches. Primary headaches due to condition itself not due to another cause e.g. migraines, tension, cluster headaches. Secondary headaches to do with different presentation, so a diff condition, so secondary to a haemorrhage or infections like meningitis, and medication-overuse is also classed as secondary.”

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6
Q

6 - Most important thing to know by the end of the assessment:

A

Most important thing to know by the end of the assessment:
• How worried you are about the cause of the headache?
• What you are going to do next?
• Investigations?
• Start some treatment?
• Send to specialist?
• Send straight to A+E?

“So point of hx and exam, is you want to know how worried are you about cause of headache, and what are you going to do next – investigations, treatment or straight to A&E/specialist for urgent referral?”

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7
Q

7 - Headache History and Examination

A

Headache History and Examination

History
• HPC: SOCRATES/ SQITARS
• Causal factors/ triggers
• PMHx: problems related to headaches i.e. previous history
• DHx: analgesia/ drugs that give headache as a side effect
• FHx
• SHx: stress, eating, dehydration
• Red Flags

Examination
• Observations
• Neuro (peripheral and cranial)
• Any related system depending on what you are worried about

“So, hx always the same, pain hx – with headache, want to know where it is, does it go anywhere, what does it feel like, how intense is the headache – timing of headache how long does it last anything makes it better or worse for the headache/in general and any associated symptoms. Also with headaches think about causal factors, lots of triggers for headaches, common ones include sleep disturbance, stress, certain foods e.g. cheese, coffee, wine etc. v common causes of headache. You want to know is this the first time or something they’ve had chronically over a number of years. If getting headaches how much medication they’re taking – are they straying into medication over-use side of headaches - or started medication a few months ago and actually a side effect? If it runs in the family? Any social history: causal factors and triggers. And also red flags we’ll come back to in a lil while. For Eeaminations of headaches – do obs, do temp for any signs of infection, any neurological deficit do full neuro exam (peripheral and cranial nerves) – and if cause involves diff system then examine that system as well, but most commonly just do neurological examination.”

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8
Q

8 - Differential Of Headaches

[slide]

A

Differential Of Headaches

ACUTE
• VASCULAR: Haemorrhage: SAH, intracranial bleed, sinus venous thrombosis
•INFECTION/INFLAMMATION: Meningitis, Encephalitis, Abscess
• OPHTHALMIC: Acute glaucoma
• SITUATIONAL: cough, exertion, coitus

CHRONIC
• MIGRAINE
• CLUSTER HEADACHES
• DRUGS: Analgesics, Caffeine, Vasodilators (i.e. side effects of other drugs)
• TENSION HEADACHES
• NEURALGIA (TRIGEMINAL)
• ICP ↑: tumours
• GIANT CELL ARTERITIS
• SYSTEMIC: HTN (pheochromocytoma, pre- eclampsia)
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9
Q

9 - Differential Of Headaches

A+E

A

Differential Of Headaches
Go to A+E/ for emergency assessment (*)

ACUTE
• *VASCULAR: Haemorrhage: SAH, intracranial bleed, sinus venous thrombosis
• *INFECTION/INFLAMMATION: Meningitis, Encephalitis, Abscess
• *OPHTHALMIC: Acute glaucoma
• SITUATIONAL: cough, exertion, coitus

CHRONIC
• MIGRAINE
• CLUSTER HEADACHES
• DRUGS: Analgesics, Caffeine, Vasodilators (i.e. side effects of other drugs)
• TENSION HEADACHES
• NEURALGIA (TRIGEMINAL)
• *ICP ↑: tumours
• *GIANT CELL ARTERITIS
• *SYSTEMIC: HTN (pheochromocytoma, pre- eclampsia)

“The ones that we’re flagging up now in orange = acute headaches: ones to be super worried about and ruling out with history. Things like bleeds or infections and acute-angle glaucoma: need to go straight to A&E. RICP if stable for a number of weeks then potentially just 2-week wait referral but any new seizures, changes in consciousness level for example, send them straight to A&E. GCA but generally can start some treatment acutely, acute corticosteroids, but need to be seen by a specialist in hosp within 24-48 hrs. Systemic – depends on what you think the cause is whether you do a 2-week wait or straight to hospital e.g. straight to hosp for pre-eclampsia.”

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10
Q

10 - Red Flag symptoms of Headache

[speech]

A

Red Flag symptoms of Headache
• Aimed at picking up emergencies and malignancies

Box 1. The SNOOP mnemonic may catch potentially life-threatening headaches
Systemic signs and disorders 50 years old 50 needs to be a BIG RED FLAG: we’ll talk about epidemiology of common benign headaches, you’ll see that 50 y/o quite late for these headaches: even if PMHx of headaches if this is NEW and DIFFERENT be worried about MALIGNANCY. Onset in Thunderclap presentation, vascular presentation, get a SAH lecture later on, we mean sudden onset, reaches intensity within a couple of seconds, worse headache they’ve ever had – patient commonly says things like “feel like I’ve been whacked over the back of the head” – quickness of headache. And then thinking about any symptoms of RICP such as papilledema, do you need to check the eyes as part of your neurological examination. So again you’ve got a future lecture on RICP but we’ll just”

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11
Q

11 - Red Flag symptoms of Headache

[slide]

A

Red Flag symptoms of Headache
• Aimed at picking up emergencies and malignancies

Box 1. The SNOOP mnemonic may catch potentially life-threatening headaches
Systemic signs and disorders 50 years old

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12
Q

12

A
Space occupying lesion symptoms
• Gradual onset
• Progressive
• Associated neurology
• Change in vision
• Features of increased ICP
• Early morning headache
• N+V
• Worse on coughing or bending
https://www.fotosearch.com/CSP992/k13365758/
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13
Q

13

A
Patient Case
Rachel, a 24 year old female comes to you,
as her GP, with headaches.
They have been going on for 2
months on and off. She gets about
1 a month. She gets a throbbing in
her head and fuzzy lines in her
vision. She vomits and light hurts
her eyes. They go after about 6
hours. The pain relief she had tried
isn’t helping very much. 
Think for a moment about your
differential diagnosis
Any red flags from that history?
Any other questions you would ask?
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14
Q

14

A
Patient Case
Rachel, a 24 year old female comes to you,
as her GP, with headaches.
They have been going on for 2
months on and off. She gets about
1 a month. She gets a throbbing in
her head and fuzzy lines in her
vision. She vomits and light hurts
her eyes. They go after about 6
hours. The pain relief she had tried
isn’t helping very much. 
Think for a moment about your
differential diagnosis
Any red flags from that history?
Any other questions you would ask?
Other questions:
- Other red flags e.g. worse in the
morning
- How much medication she is taking/
new medications
- Precipitants to headache
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15
Q

15

A
Patient Case
Rachel, a 24 year old female comes to you,
as her GP, with headaches.
They have been going on for 2
months on and off. She gets about
1 a month. She gets a throbbing in
her head and fuzzy lines in her
vision. She vomits and light hurts
her eyes. They go after about 6
hours. The pain relief she had tried
isn’t helping very much.
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16
Q

16

A
Patient Case
Rachel, a 24 year old female comes to you,
as her GP, with headaches.
They have been going on for 2
months on and off. She gets about
1 a month. She gets a throbbing in
her head and fuzzy lines in her
vision. She vomits and light hurts
her eyes. They go after about 6
hours. The pain relief she had tried
isn’t helping very much. 
Throbbing is only on one side of her
head. Vomiting and photophobia is
only when the headache is present.
She has only taken paracetamol
and only when she has the
headache. Not used every day.
Nothing seems to bring it on except
maybe that she has been a bit
more stressed lately. No early
morning headache
• Examination findings:
• Temp 37.4, HR 68, BP 110/75, RR16,
sats 98%
• No neurological deficit
• No papilloedema
17
Q

17

A

Differential Of Headaches

ACUTE
• VASCULAR: Haemorrhage: SAH, intracranial bleed, sinus venous thrombosis
• INFECTION/INFLAMMATION: Meningitis, Encephalitis, Abscess
• OPHTHALMIC: Acute glaucoma
• SITUATIONAL: cough, exertion, coitus

CHRONIC
• MIGRAINE
• CLUSTER HEADACHES
• DRUGS: Analgesics, Caffeine, Vasodilators (i.e. side effects of other drugs)
• TENSION HEADACHES
• NEURALGIA (TRIGEMINAL)
• ICP ↑: tumours
• GIANT CELL ARTERITIS
• SYSTEMIC: HTN (pheochromocytoma, pre- eclampsia)
18
Q

18

A

Differential Of Headaches

ACUTE
• VASCULAR: Haemorrhage: SAH, intracranial bleed, sinus venous thrombosis
• INFECTION/INFLAMMATION: Meningitis, Encephalitis, Abscess
• OPHTHALMIC: Acute glaucoma
• SITUATIONAL: cough, exertion, coitus

CHRONIC
• *MIGRAINE*
• CLUSTER HEADACHES
• DRUGS: Analgesics, Caffeine, Vasodilators (i.e. side effects of other drugs)
• TENSION HEADACHES
• NEURALGIA (TRIGEMINAL)
• ICP ↑: tumours
• GIANT CELL ARTERITIS
• SYSTEMIC: HTN (pheochromocytoma, pre- eclampsia)
19
Q

19

A

Differential Of Headaches

Covered in other sessions

CHRONIC
• MIGRAINE
• CLUSTER HEADACHES
• DRUGS: Analgesics, Caffeine, Vasodilators (i.e. side effects of other drugs)
• TENSION HEADACHES
• NEURALGIA (TRIGEMINAL)

Covered in other sessions

20
Q

20

A

Migraine
Epidemiology
2% general population have chronic migraines
Females > males (6% males, 18% females)
80% have had first attack by 30
Severity tends to decrease as age increases
S – Unilateral, often frontal
Q – Sudden or gradual onset, Throbbing/ pulsating
I – Moderate
T – Between 4 and 72 hours. May be cyclical
A – Photo/phonophobia
R – Sleep make better, medication
S - +/- aura, N+V
Triggers: Food, sleep, stress
Often has FHx
?Cause – vascular dysfunction vs neuronal dysfunction

21
Q

21

A
Tension Type Headache
Epidemiology
Most common type of headache
Females >males
Young > old
First onset > 50 unusual
 – Bilateral, frontal (vertex-bitemporal)
Q – Squeezing, non-pulsatile
I – Less severe (mild-moderate)
T – Worse at the end of the day. ? Less
than 15 times per month
A – stress, poor posture, lack of sleep
R – ? To neck
S – mild nausea
No FHx
Usually responsive to OTC medication
22
Q

22

A

Medication Overuse Headache
Epidemiology
3rd most common type of headache
1-2% UK population
20% population who have headaches
30-40 years old
Females>males
• Defined as headache present on at least 15 days per month
• Does not improve after OTC medication
• Regular overuse greater than 3 months of one of the following:
• Triptans or opioids (codeine) on at least 10 days of the month
• Paracetamol, aspirin or NSAIDs on at least 15 days of the month
• Resolves completely after 2 months following discontinuation of
medication
• Initially may get worse before it gets better

23
Q

23

A
Medication Overuse Headache
Epidemiology
3rd most common type of headache
1-2% UK population
20% population who have headaches
30-40 years old
Females>males
• Headache mechanism is thought to be an increase in headache pain
receptors
• Mixed symptoms
• Often co-existing with depression/ sleep disturbance
• Difficult to manage
• Might get withdrawal
24
Q

24

A
Cluster Headache
Epidemiology
1/1000 people
Males>females
Usually begins 20-40 years old
 – Around/behind one eye
Q – sharp, penetrating
I –Very severe and constant intensity
T – Rapid onset. Attacks last 15min–3hrs,
1-2x/day, mostly nocturnal.
• Clusters last 2-12wks, remission lasts
3mo-3yrs
• Can be chronic vs. episodic
A – head injury, alcohol, cigarette smoking
R – No radiation
S – Red, watery eye, nasal congestion
Triggers: Alcohol, histamine, GTN, heat,
exercise, solvents, lack of sleep
25
Q

25

A

Trigeminal Neuralgia
Epidemiology
Peak incidence 50-60
Prevalence increases with age
~25/100,000 UK population
Females > males
90-95% caused by compression of CNV by loop of artery or vein
5% attributed to tumours, MS, skull base abnormalities or AV
malformations
S – unilateral, often over the eye
Q – stabbing, sharp, “electric shock”
I – severe
T – sudden onset, lasts a few seconds to 2 minutes
A – light touch to face, eating, cold wind, vibrations
R – radiates to eyes, lips, nose and scalp
Preceding symptoms: tingling, numbness
More common with PHx chronic pain

26
Q

26

A

Most important thing to know by the end of the assessment:
• How worried you are about the cause of the headache?
• What you are going to do next?
• Investigations?
• Start some treatment?
• Send to specialist?
• Send straight to A+E?

27
Q

27

A
Most important thing to know by the end of the assessment:
• How worried you are about the cause of the headache?
• What you are going to do next?
• Investigations?
• Start some treatment?
• Send to specialist?
• Send straight to A+E?
How worried is your patient/ how much is
the headache affecting their life?
28
Q

28

A

Most important thing to know by the end of the assessment:
• How worried you are about the cause of the headache?
• What you are going to do next?
Investigations?
• Start some treatment?
• Send to specialist?
• Send straight to A+E?

29
Q

29

A

Most important thing to know by the end of
the assessment:
• How worried you are about the cause of the headache?
• What you are going to do next?
• Investigations?
Headache diary
Imaging- CT/ MRI

30
Q

30

A
Most important thing to know by the end of
the assessment:
• How worried you are about the cause of the headache?
• What you are going to do next?
• Investigations?
• Start some treatment?
Simple analgesia
Migraine: Triptans
Cluster headaches: High
flow oxygen
31
Q

31

A

Most important thing to know by the end of
the assessment:
• How worried you are about the cause of the headache?
• What you are going to do next?
• Investigations?
• Start some treatment?
• Send to specialist?

32
Q

32

A

Referral Criteria
Refer urgently patients with:
• Symptoms related to the CNS in whom a brain tumour is
suspected, including:
• progressive neurological deficit
• new-onset seizures
• headaches
• mental changes
• cranial nerve palsy
• unilateral sensorineural deafness
• Headaches of recent onset accompanied by features
suggestive of raised intracranial pressure, for example:
• vomiting
• drowsiness
• posture-related headache
• pulse-synchronous tinnitus
• or by other focal or non-focal neurological symptoms, for example blackout, change in personality or memory
• Suspected recent-onset seizures (refer to neurologist)
• Refer urgently patients previously diagnosed with any
cancer who develop any of new onset neurological
symptoms
Consider urgent referral (to an appropriate
specialist) in patients with rapid
progression of:
• subacute focal neurological deficit
• unexplained cognitive impairment,
behavioural disturbance or slowness, or a
combination of these
• personality changes confirmed by a witness
and for which there is no reasonable
explanation even in the absence of the other
symptoms and signs of a brain tumour
• Consider non-urgent referral or discussion with specialist for:
• unexplained headaches of recent onset:
• present for at least 1 month
• not accompanied by features suggestive of
raised intracranial pressure.

33
Q

33

A

Any Questions?

Thank You

34
Q

34

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