Session 5 - Blood Flow Flashcards

1
Q

Define Veloicty

A

The rate of movement of fluid particles along the tube

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2
Q

What is the relationship between flow, volume and time?

A

Flow = Volume / Time

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3
Q

What is laminate flow?

A

The most common type of blood flow. The velocity is. Highest in the centre and there is a gradient out to the edges

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4
Q

What is turbulent flow?

A

If mean velocity increases eventually blood will become turbulent. The velocity gradient breaks down and the fluid layers begin to tumble over one another with a great increase in flow resistance

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5
Q

Define viscosity

A

Extent to which fluid layers resist sliding over one another

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6
Q

What will happen to velocity if viscosity increases?

A

The velocity will decrease

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7
Q

How does diameter of the tube effect velocity?

A

If diameter of the tube increases the middle layers of the fluid will flow faster and hence the average velocity will increase

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8
Q

What is relationship between flow, resistance and pressure?

A

Pressure = Flow x Resistance

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9
Q

What is the relationship between resistance and radius?

A

The resistance decreases with thee fourth power of the radius

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10
Q

How do we work out total resistance of tubes in series?

A

We simply sum together the resistances of each tube

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11
Q

How do we work out the total resistance of tubes in parallel?

A

1/total resistance = 1/one tubes resistance + 1/other tubes resistance

(Add 1/tube resistance for all tubes in parallel)

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12
Q

Which vessels of the body have the highest resistance?

A

Arterioles

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13
Q

What makes the arteries have a high pressure?

A

Arterioles have a high resistance which means that when the heart pumps it is difficult for the blood to pass into the Arterioles so pressure in the arteries rises.

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14
Q

What will happen in a distensible blood vessel if pressure decreases too low?

A

The wall will eventually collapse and blood flow ceases.

This happens before pressure falls to zero

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15
Q

What feature of vessels allow them to have capacitance?

A

As vessels widen, more blood transiently flows in than out

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16
Q

What is the systolic pressure? And what is its typical value?

A

The maximum arterial pressure

120mmHg

17
Q

What is systolic blood pressure effected by?

A
  • How hard the heart pumps
  • Total Peripheral resistance
  • Compliance of arteries
18
Q

What is diastolic pressure? And what is a typical value for it?

A

The minimum arterial pressure

80mmHg

19
Q

What is diastolic pressure affected by?

A

Systolic pressure

Total peripheral resistance

20
Q

What is pulse pressure?

A

The difference between systolic and diastolic pressure

21
Q

What is average pressure?

A

Diastolic pressure + 1/3 pulse pressure

22
Q

What is the total peripheral resistance?

A

The sum of the resistance of all of the peripheral vasculature in the systemic circulation

23
Q

What is a pulse wave?

A

The contraction of the ventricles generates a pulse wave which propagates along the arteries faster than the blood.

24
Q

How can Arterioles act as the main resistance vessels?

A

Arterioles contain smooth muscle and its state of contraction determines lumen diameter and flow resistance

25
Q

What is vasomotor tone?

A

The continuous contraction of blood vessels

26
Q

Name some vasodilator metabolites?

A
  • Hydrogen ions
  • Potassium ions
  • Adenosine
27
Q

How does hyperaemia occur?

A

If circulation is cut off for a minute or two to an organ, and then blood flow returns, local vasodilator metabolites will be at a very high concentration. This means that the vessels will dilate to the maximum potential.

28
Q

What is central venous pressure?

A

The pressure in the great veins supplying the heart

29
Q

What is Venous Return?

A

Th rate of blood flow back to the heart. This limits cardiac output

30
Q

Define Flow

A

The volume of fluid passing a given point per unit time