Session 4 - Antibiotics and Antimicrobial stewardship

Question 1

Outline the relevant anatomy of the cerebrospinal fluid (CSF)

Answer 1

The CSF is a protective cushion of cerebrospinal fluid (CSF) which flows within the subarachnoid space, beneath the arachnoid membrane, on top of the pia mater.

It also surrounds the spinal cord and fills the ventricles inside the brain and helps to maintain a constant pressure inside the skull.

Question 2

Describe the biochemical and cellular composition of CSF and diagnostic comparison in meningitis

Answer 2

Cerebrospinal fluid is produced by the choroid plexus, located in the lining of the ventricles. It consists of capillaries and loose connective tissue.

Plasma is filtered from the blood by the epithelial cells to produce CSF. In this way, the exact chemical composition of the fluid can be controlled.

Cerebrospinal fluid (CSF) is a clear, plasma-like fluid. It contains glucose (about 2/3rds that of the blood) and some protein. There are few or no cells (any that there are - are likely to be lymphocytes).

In Meningitis - it depends on the type of infection
SEE NOTES - but i do need to know!!