Session 2 - Lecture 1

Question 1

1

Answer 1

1

Question 2

3 - DNA replication - termination

Answer 2

Prokaryotic DNA – circular. Terminates when two replication forks meet each other.

Question 3

4 - DNA Replication – Termination (CONTENT)

Answer 3

Two leading strands and two lagging strands. DNA ligase repairs all the gaps

Question 4

5 - DNA replication - termination - model

Answer 4

All DNA strands identical

Old strand is existing, template strand

Semi-conservative model of DNA replication most likely in making an identical copy, don’t want mistakes because this process is so important

Question 5

6 - DNA replication - prokaryotes

Answer 5

Summary in prokaryotes:

Two replication forks meet and DNA ligase joins all the fragments together

Question 6

7 - DNA replication eukaryotes

Answer 6

Eukaryotes have chromosomes with long dsDNA, not circular

DNA replication begins at specific Origins of Replication sequences

Replication occurs in both directions

Chromosome is eventually replicated; now one chromosome with two DNA molecules (as opposed to one)

Note nomenclature: still 46 chromosomes after replication, but each now consists of two identical DNA molecules

Question 7

8 - Nomenclature

Answer 7

Highly condensed chromosome

Replicated chromosomes with two identical DNA molecules – becomes two sister chromatids held together by a centromere

Classical X shape chromosome – just gone through replication. Two identical DNA molecules (two sister chromatids)

Question 8

8

Answer 8

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Question 9

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Answer 9

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Question 10

10

Answer 10

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Question 11

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Answer 11

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Question 12

12

Answer 12

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Question 13

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Answer 13

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Question 14

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Answer 14

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Question 15

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Answer 15

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Question 16

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Answer 16

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Question 17

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Answer 17

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Question 18

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Answer 18

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Question 19

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Answer 19

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Question 20

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Answer 20

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Question 21

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Answer 21

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