Session 2 Flashcards

The heart as a pump and CVS development

1
Q

Left atrioventricular valve?

A

mitral/bicuspid

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2
Q

Right atrioventricular valve?

A

tricuspid

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3
Q

Left Outflow valve?

A

aortic

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4
Q

Right outflow valve?

A

Pulmonary

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5
Q

Which ion enters cell during action potential?

A

calcium

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6
Q

Length of action potential/systole?

A

280ms

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7
Q

What do pacemakers do?

A

generate an action potential at regular intervals

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8
Q

What is the spread of excitation

A

SAN (right atrium) -> atria (atrial systole) -> AVN (120ms delay) -> septum -> ventricular myocardium from endocardium to epicardial surface (contraction from apex up)

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9
Q

When does the left ventricle open and close?

A

Intra-ventricular pressure exceeds aortic pressure (closes when aortic pressure>intra-ventricular pressure

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10
Q

The cardiac cycle - start?

A
(end of ventricular systole)
Ventricles contracted
ventricular pressure high, outflow valves open
blood flowing into arteries
A/V valve closed
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11
Q

The cardiac cycle - 2

A
Ventricles relax
ventricular pressure falls
brief backflow closes valves
all valves closed
"isovolumentric relaxation"
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12
Q

The cardiac cycle - 3

A

During systole, blood has continued to return to atria
Atrial pressure high
ventricular pressure falls below atrial pressure
AV valves open

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13
Q

The cardiac cycle - 4

A

With the A/V valves open -

ventricles fill rapidly (rapid filling phase ~ 200-300ms)

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14
Q

The cardiac cycle - 5

A

Diastole continues - ventricles fill more slowly
Ventricular pressure rises as ventricular walls stretch
When ventricular pressure equals atrial pressure, filling stops

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15
Q

The cardiac cycle - 6

A

Atrial systole
Forces a small extra amount of blood into ventricles
(heart can still function without atrial systole)

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16
Q

The cardiac cycle - 7

A
Ventricular systole
ventricular pressure rises very rapidly
exceeds atrial pressure
after brief backflow, AV valves close
all valves closed
"isovolumetric contraction"
17
Q

The cardiac cycle - 8

A

Ventricular pressure rises very rapidly

outflow valves open

18
Q

The cardiac cycle – 9

A

Blood is ejected into the arteries (rapid ejection phase)

Arterial pressure rises rapidly

19
Q

The cardiac cycle - 10

A

As arterial pressure rises
Rate of ejection of blood falls
outflow ceases with blood still in ventricle

20
Q

The cardiac cycle - 11

A

systole ends

21
Q

Heart sounds? (2)

A

‘lup’ closure of A/V valves
‘dup’ closure of outflow valves
interval between sounds -280ms
interval to next - 700ms

22
Q

Cardiac Output?

A

Stroke volume x heart rate = cardiac output /l.min-1