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farmacología final > sesibilizadores a la insulina diabetes > Flashcards

sesibilizadores a la insulina diabetes Flashcards

1
Q

se dividen

A

biguanidas
Tiazolidinedionas

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2
Q

biguanidas es

A

metformina

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3
Q

tiazolidinedionas

A

rosiglitazona
pioglitazona

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4
Q

metfomina mecanismo de acción

A

aumenta AMPK
gluconeogenesis
sensibilizacion
betaoccidacion
disminuye la absocion de glucosa en el intestino

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5
Q

tizolideionas mecanismo de accion

A

sensibilizacion
agonistas del PPARy
glut 4 musculo y tejido adiposo
captacion acidos grasos

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6
Q

biguanida metformina indicaciones

A

primera linea para DM2
obesidad
baja el riego de mortalidad y progresion

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7
Q

tiazolidineodionas pioglitazona y rosiglitazona Indicaciones

A

No tan recomendado por sus efectos adversos

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8
Q

ADME biguanida metformina

A

alimentos retrasan la absorcion

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9
Q

biguanida metformina efectos adversos gastrointestinales

A

nauseas, vomito, diarrea, dispepsia, anorexia, flatulencias, perdida de peso

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10
Q

biguanida metformina y bitamina b12

A

Retrasa su absorcion

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11
Q

biguanida metformina EA raros

A

acidosis lactica
CDK
daño hepatico grave

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12
Q

biguanida metformina y etanol

A

aumenta la toxicidad de la metformina

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13
Q

Efectos adversos tiazolidiedionas pioglitazona y rosiglitazona

A

edema - ICC
adiposidad central
subir de peso

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14
Q

efectos adversos de rosiglitazonas

A

cardiacos
daño oseo fractura

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15
Q

efectos adversos de pioglitazona

A

cancer vesical
edema macular

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farmacología final (18 decks)

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