diabetes incretinas Flashcards

1
Q

mimeticos de las incretinas MoA

A

analogos de la GLP1

aumento liberacion de la insulina
disminuye el glucagon

retrasa vaciamiento gastrico

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2
Q

mimeticos de las incretinas cuales son

A

Exenatida
Liraglutida
Lixisenatida

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3
Q

mimeticos de las incretinas (exenatida, liraglutida y lixisenatida) indicaciones generales

A

hipoglucemiantes orales

mejora metformina, tiazolideionas y sulfonilureas

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4
Q

mimeticos de las incretinos (exenatida ADME)

A

vida media corta

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5
Q

Mimeticos de las incretinas (liraglutida y lixisenatida) ADME

A

vida media larga

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6
Q

miemticos de las incretinas (exenatida, liraglutida y lixisenatida) EA

A

nauseas
pancreatitis

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7
Q

mimeticos de las incretinas semaglutida indicaciones

A

reducción de enfermedades cardiovasculares

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8
Q

Inhibidores de las DDP4 cuales son

A

sitagliptina
saxagliptina

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9
Q

inhibidores de las DDP4 (sitagliptina
saxagliptina) MoA

A

inhibidores de las DPP4
aumento de la concentracion y vida de GLP1

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10
Q

inhibidores de las DDP4 (sitagliptina
saxagliptina) Indicaciones

A

coadyuvante de hipoglucemiantes
ancianos y fragiles
monoterapia

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11
Q

inhibidores de las DDP4 (sitagliptina
saxagliptina) EA

A

flu like symptoms
alteraciones GI

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