Seronegative inflammatory arthropathies Flashcards
Ank. spond. symptoms
Spinal pain
Morning stiffness that improves with exercise
Possible also knee/hip arthritis
What is ank spond?
Inflammation of the spine and sacroiliac joints
Most common demographic for ank spond?
Males 20-40
Ank spond signs
Question mark spine
- increased thoracic kyphosis, loss of lumbar lordosis
Associated conditions of ank spond
Anterior uveitis
Aortitis
Pulmonary fibrosis
Amyloidosis
Ank spond x-ray findings
Sclerosis and fusion of SI joints
Syndesmophytes bridging intervertebral discs = bamboo spine
Possibly normal at presentation
Ank spond treatment
Exercise Physio NSAIDs Anti TNF for aggressive disease DMARDs for peripheral joint inflammation if present
Which gene is strongly associated with ank spond?
HLA-B27
Psoriatic arthritis symptoms?
Affects hands similarly to RA
Nail changes
- pitting
- onycholysis
Psoriatic arthritis treatment?
Similar to that of RA
- DMARDs progressing to anti-TNF in aggressive cases
In which patients does enteropathic arthritis occcur?
Patients with IBD
- crohns or UC
Which joints does enteropathic arthritis affect?
Peripheral joints and spine
What causes reactive arthritis?
Infection elsewhere
- commonly genitourinary (chlamydia) or GI tract (salmonella, campylobacter)
When does reactive arthritis occur?
Around 1-3 weeks post infection
Patients with reactive arthritis also often suffer from Reiters syndrome, what is the triad of symptoms in Reiters syndrome?
Arthritiis
Uveitis
Urethritis
