Serious and Common Adverse Effects

Question 1

What are the serious and common adverse effects of colchicine?

Answer 1

myelosuppression, neuromyopathy

diarrhea, nausea, abdominal pain

Question 2

What are the serious and common adverse effects of allopurinol and oxypurinol?

Answer 2

agranulocytosis, aplastic anemia, renal failure, hepatic necrosis, Stevens-Johnson syndrome, toxic epidermal necrolysis
pruritus, rash, GI disturbances

Question 3

What are the serious and common adverse effects of febuxostat?

Answer 3

MI, stroke

abnormal liver enzymes

Question 4

What are the serious and common adverse effects of sulfinpyrazone and probenecid?

Answer 4

leukopenia, thrombocytopenia, bronchoconstriction in patients with asthma
probenecid only: aplastic anemia, hepatic necorsis, anaphylaxis
GI disturbances

Question 5

What are the serious and common adverse effects of losartan?

Answer 5

angioedema, rhabdomyolysis, thrombocytopenia

anemia, fatigue, back pain, hypoglycemia

Question 6

What are the serious and common adverse effects of rasburicase and pegloticase?

Answer 6

hemolysis, methemoglobinemia, neutropenia, respiratory distress, sepsis
rash, GI disturbance, fever