Sept 22 recall

Question 1

Which immunosuppressive drugs increase your risk of GDM?

Answer 1

Tacrolimus and ciclosporin
Steroids

Question 2

If previously had a baby affected by congenital heart block and positive for anti ro/la, what medicine can be given prophylactically?

Answer 2

Hydroxychloroquine

Question 3

Which AED gives the least risk of SGA?

Answer 3

Lamotrigine

Question 4

Which medications offer the least likelihood of congenital malformations?

Answer 4

lamotrigine and carbamazepine
(carbamazepine associated with cleft palate)

Question 5

Which AED drugs were NOT associated with reduced IQ

Answer 5

Lamotrigine, carbamazepine, phenytoin

Question 6

When do you monitor lamotrigine levels?

Answer 6

In pregnancy they can be reduced by 70%
And use of the CHC can reduce the level

Question 7

When should you taper the dose of AEDs postpartum?

Answer 7

10 days

Question 8

WWE taking AEDs- inc risk of FGR in general?

Answer 8

3.5X

Question 9

when to offer cont cTG in obstetric cholestasis?

Answer 9

if BA >100

Question 10

What is the sensitivity for NT alone for T21 testing?

Answer 10

77%
FPR 5%

Question 11

What is the safest b blocker to use for heart failure in pregnancy?

Answer 11

Metoprolol
Avoid spironocactone
Can use hydralazine, nitrates and furosemide but there is a risk of uterine hypoperfusion

Question 12

Reasons for failure of NIPT?

Answer 12

placental mosaicism
Low fetal DNA level
Vanishing twin

Question 13

Risk of a 3rd or 4th degree tear recurrence?

Answer 13

6%

Question 14

Risk of worsening symptoms in further vaginal birth?

Answer 14

17%