Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

CCP S2 > sepsis > Flashcards

sepsis Flashcards

1
Q

reason for more sepsis cases

A
  • better capture
  • age
  • immunocomprimise
  • more resistant bug
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

sepsis

A

life threatening organ dysfunction (2 or more qsofa) causes by host response to an infection

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

qSOFA

A

RR> 22
DLOC
SBP< 100

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

septic shock

A

require a pressor to maintain a MAP> 65 lactate >2

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

what type of infections are commonly found in RTIs?

A

gram + and -

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

what type of infections are commonly found subdiagphamatic

A

aerobic and gram -

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

what type of infections are commonly found in UTIs

A

gram -

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

what type of infections are commonly found in skin infections?

A

gram +

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

what type of infections are commonly found in RTIs?

A

gram + and -

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

what type of infections are commonly found in UTIs

A

gram -

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

what type of infections are commonly found in skin infections?

A

gram +

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

steps of the innate immune response

A

1- pathogen breaches skin
2- macrophages and mast cells respond to area
3- mast cells cause inflammation
2- macrophages ingest the pathogen and release cytokines
3- cytokines attract basophils/eosinophils/ more mast cells and cause local edema and increased permeability
4- cytokines cause neutrophils to stick to endothelium and invest pathogens at the site, neutrophils die to create pus

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

steps of adaptive immune response

A

1- dendritic antigen presenting cells absorb pathogen and present it on its surface
2- the APC enters lymphatic circulation to lymph nodes
3- in the lymph node, the APC attaches to help T cells where antibodies are created
4- If the pathogen itself enters lymphatic tissue, B cells will bind to them and create antibodies
5- T cells will create cytotoxic t cells which enter circulation with the antibody
6- B cell will create effector cells/antibodies
7- cytotoxic T cells and antibodies will travel to the site of infection and either neutralize or tagged them for destruction

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

SIRS vs Sepsis vs Severe sepsis vs Septic shock vs MODS

A

SIRS- fever, RR> 20, HR>90, WBC elevation,
Sepsis- 2 SIRS + infection confirmation
Severe sepsis- Sepsis + signs of hypo perfusion (no longer used)
Septic Shock- Severe sepsis refractory to appropriate fluid resuscitation
MODS- Failure of 2 or more organs

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

SIRS criteria

A 
36> temp> 38
RR> 22
HR> 90
4000> WBC >12000
2 or more to qualify
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

qsofa

A

RR > 20
GCS < 14
SBP < 100
2 or more to qualify

17
Q

types of gram + bacteria

A

MRSA
Strep
Staf

18
Q

types of gram - bacteria

A

space bugs
Ecoli
Salomella

19
Q

early goal directed therapy

A

SBP< 90, MAP<65 after 30ml/kg crystalloid , lactate >4

CVP 8-12&raquo_space; give crystalloids to maintain >8
MAP >65»»epi or dope to maintain
SCVO2 > 70»»if less than 70 give PRBC to hematocrit> 30, if SCVO2 < 70 despite SCVO2 > give inotrope to SCO2 > 70

20
Q

normal lactate clearance

A

20%/hr

21
Q

SOFA criertia

A 
Points based on deviation form normal
PaO2/FiO2:  400
Plt: 150
liver, bili: 1.2
cardiovascular, MAP: 70
CNS, GCS: 15
renal, creatinine/urine output: 1.2
22
Q

when are Glucocorticoids recommended in sepsis management

A

septic shock that is refractory to adequate fluid resuscitation and vasopressor administration

23
Q

what should you consider prior to starting ABX in sepsis patients

A
  • pt hx ( recent antibiotics received, previous organisms)
  • comorbidities (DM, renal failure)
  • immunocomprimise
  • clinical context (eg, community- or hospital-acquired)
  • suspected site of infection
  • presence of invasive devices
  • Gram stain data
  • local prevalence and resistance patterns
24
Q

ABX therapy in sepsis

A

Coverage should be directed against both gram-positive and gram-negative bacteria and, if indicated, against fungi (eg, Candida) and rarely viruses (eg, influenza)

25
Q

what does penicillin do

A

attacks cell walls

26
Q

what does fluroquiolone do

A

attacks dna

27
Q

what does metronitozol do

A

reduces bacterial growth

28
Q

what do myacins do

A

flows growth of bacteria

CCP S2 (10 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2024 Bold Learning Solutions. Terms and Conditions