Sepsis

Question 1

Define Sepsis:

Answer 1

Life-threatening organ dysfunction caused by a dysregulated host response to infection.

Question 2

Define Septic Shock:

Answer 2

Persistent hypotension requiring vasopressors to maintain mean arterial pressure > 65 mmHg and having a lactate > 2 mmol/L despite adequate volume resuscitation.

Question 3

List the Sepsis management goals:

Answer 3

early suspicion and recognition 
Source identification 
Early antimicrobial therapy 
Resuscitation 
Source control
patient monitoring through trending patient information
Early telemedicine consultation 
Evacuate to definitive care

Question 4

What is the acronym SIRS?

Answer 4

systemic inflammatory response syndrome

Question 5

although not used for defining sepsis, what are the four criteria of SIRS?

Answer 5

tachycardia (HR > 90)
tachypena (RR > 20 / PaCO2 < 32 mmHg)
Fever or hypothermia
Leukocytosis or Leukopenia

Question 6

What are the two sepsis screening tools?

Answer 6

qSOFA

NEWS2 score

Question 7

what are the three indicators of qSOFA that inreae the index of suspicion for sepsis?

Answer 7

altered mental status
tachypena
hypotension