Semi-known Exam Questions Flashcards

1
Q

Requirements of Radioimmunoassay (4)

A
  1. A solution containing the suspect drug of abuse
  2. Antibody specific to that drug of abuse
  3. Control sample of suspect drug radioactive labelled with (125)I
  4. A means of measuring radioactive emissions from the decay of (125)I
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2
Q

Define Post Mortem Redistribution

A

The processes that occur to the drugs which lead to the change in their concentrations after death

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3
Q

Describe Transporters

A

Inhibitors on the outside of the cell that often behave like receptors except they transport in and out the cell

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4
Q

U-Glucuronidation

A

Carboxylic acid
Phenols
Alcohols

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5
Q

N-Glucuronidation

A

Amines
Amides
Sulphonamides

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