Semi-known Exam Questions Flashcards
1
Q
Requirements of Radioimmunoassay (4)
A
- A solution containing the suspect drug of abuse
- Antibody specific to that drug of abuse
- Control sample of suspect drug radioactive labelled with (125)I
- A means of measuring radioactive emissions from the decay of (125)I
2
Q
Define Post Mortem Redistribution
A
The processes that occur to the drugs which lead to the change in their concentrations after death
3
Q
Describe Transporters
A
Inhibitors on the outside of the cell that often behave like receptors except they transport in and out the cell
4
Q
U-Glucuronidation
A
Carboxylic acid
Phenols
Alcohols
5
Q
N-Glucuronidation
A
Amines
Amides
Sulphonamides