Sem 6

Question 1

What drugs were withdrawn from the market and why

Answer 1

Rofecoxib and valdecoxib (NSAIDS
s)
Because serious cardiovascular events have been associated with COX-2 inhibitors

Question 2

Colecoxib is still available for what?

Answer 2

Treatment of RA,osteoarthritis,pain

Question 3

Which drug irreversiblly (acetylates) cyclooxygenase

Answer 3

Aspirin(NSAID)
Other NSAIDs are all reversible inhibitors of cyclooxygenase

Question 4

What are the 3 major therapeutic actions of NSAIDs

Answer 4

Anti inflammatory
Analgesic action
Antipyretic action

Question 5

Pancreas is which gland

Answer 5

Exocrine and endocrine gland

Question 6

Exocrine gland of the pancreas produce which enzyme

Answer 6

Digestive enzymes

Question 7

Endocrine gland produces what

Answer 7

Peptide hormones: insulin,glucagon and somatostatin

Question 8

The peptide hormones are secreted from cells located in…..

Answer 8

Islets of langerhans

Question 9

Beta cells produce

Answer 9

Insulin

Question 10

Alpha cells produce

Answer 10

Glucagon

Question 11

Gamma cells produce

Answer 11

Somatostatin

Question 12

What are the importance of the peptide hormones

Answer 12

They play an important role in regulating the metabolic activities of the body particularly the homeostasis of blood glucose