Sem 2 W2 - Liver diseases (MOC)

Question 1

Describe and list various types of liver disease

Answer 1

• Alcohol related liver disease
• Drug toxicity - e.g paracetemol poisening
• Hepatitis ( inflammation)
• Non-alcoholic fatty liver disease ( caused by obesity)
• Cirrhosis
• Cancer
• Gallstones
• Cholangitis - inflammation of bile duct
• Hemochromatosis - iron overload

Question 2

Describe the classification of liver disease

Answer 2

**- Acute liver disease **
- self-limiting
- Caused by - typicallydrugs /virus
- Results in - hepatocyte inflammation/damage
- IF severe results in liver failure

- Chronic liver disease
- Inflammation > 6 months
- Causes permanant damage with structural changes and can lead to cirrhosis
- COMMON CAUSE = ALCOHOL ABUSE

Question 3

Describe the progression of Liver Disease

Answer 3

1. Chronic injury occurs to a normal liver ( this can be the following; viral infection, Alcohol, NASH, Autoimmune disorders, Cholestatic disorders and Metabolic dinners )
2. Leads to inflammatoryy damage as a result of proinflammatory cytokines