Selective Serotonin Reuptake Inhibitors Flashcards
What does SSRI stand for?
Selective Serotonin Reuptake Inhibitor
True or False: SSRIs primarily increase serotonin levels in the brain.
True
Name a common therapeutic use for SSRIs.
Treatment of depression
What is the mechanism of action of SSRIs?
They inhibit the reuptake of serotonin in the brain.
Fill in the blank: SSRIs are often prescribed for ________ disorders.
anxiety
Which of the following is NOT an SSRI: Fluoxetine, Sertraline, or Amitriptyline?
Amitriptyline
What is the brand name for fluoxetine?
Prozac
List two side effects of SSRIs.
Nausea and insomnia
True or False: SSRIs can take several weeks to show therapeutic effects.
True
What is the primary neurotransmitter affected by SSRIs?
Serotonin
Name another SSRI besides fluoxetine.
Sertraline
Fill in the blank: SSRIs may help improve ________ in patients with depression.
mood
What is the brand name for sertraline?
Zoloft
True or False: SSRIs are only used for mood disorders.
False
What is a potential risk associated with discontinuing SSRIs abruptly?
Withdrawal symptoms
List one contraindication for SSRIs.
Use with MAO inhibitors
Which SSRI is often used to treat obsessive-compulsive disorder (OCD)?
Fluoxetine
Fill in the blank: SSRIs can also be effective in treating ________ disorders.
panic
What is the generic name for the SSRI known as Lexapro?
Escitalopram
True or False: SSRIs have a high potential for addiction.
False
Name a side effect that may occur with SSRIs related to sexual function.
Decreased libido
What is the brand name for citalopram?
Celexa
Fill in the blank: SSRIs are often the first-line treatment for ________ disorders.
depressive
True or False: All SSRIs have the same side effect profile.
False
What is a common reason for switching from one SSRI to another?
Ineffectiveness or side effects
List one advantage of using SSRIs over older antidepressants.
Fewer side effects
SSRI antidepressants are the first-line treatment for two disorders, can you name them?
Panic disorders and trauma and Stressor-related disorders
After five to six weeks of SSRI therapy, which later adverse effects can occur? Select All That Apply.
A. Impotence
B. Delayed or absent orgasm
C. Weight gain
D. Nausea
E. Tremor
F. Weight loss
A, B, C
SSRIs have a long or short half life?
Long half life, up to four weeks before a therapeutic medication level can be reached.
How many hours after starting Serotonin can Serotonin Syndrome begin?
A. 1 hour
B. 36 hours
C. 48 hours
D. 2 to 72 hours
D. 2–72 hours
What does a person look like with Serotonin Syndrome? Select All That Apply
A. Disorientation & hallucinations
B. Tachycardia leading to CV Shock
C. Poor concentration, & confusion & hostility
D. Headache
E. Fever & Labile B/P, Diaphoresis
F. Coma leading to Apnea and death in severe cases
A, B, C, E, & F
In persons over 65 taking diuretics and taking SSRIs what electrolyte condition can occur?
A. Hypokalemia
B. Hypocalcemia
C. Hyponatremia
C. Hyponatremia
