SEIZURES Flashcards

1
Q

If a patient states they didn’t feel well, his co-worker reports that he then collapsed, his eyes rolled in the back of his head, he then tenses up and began shaking, what diagnosis?

A

Seizure

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2
Q

What is the definition of a seizure?

A

A paroxysmal (comes and goes) event due to abnormal CNS discharge with resultant manifestations depending on area involved.

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3
Q

What is the definition of epilepsy?

A

Recurrent seizures

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4
Q

Physiologically, what’s occurring during a seizure?

A

Burst of electrical activity, influx of extracellular calcium and sodium – thus the propagation of action potentials

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5
Q

In what population are seizures most common in?

A

Children

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6
Q

If a child under the age of 5 has recurrent episodes of seizures, is it epilepsy?

A

NO

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7
Q

What are some of the triggers for seizures?

A

Fevers in children, genetics, TBI, strokes, infection, stress, sleep deprivation, meds, and menses

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8
Q

What can help you make the diagnosis of a seizure?

A

History is key, EEG, MRI (to R/O structural abnormalities), prolactin levels, possibly a lumbar puncture (if infection is suspected)

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9
Q

What are the two basic type of seizures?

A

partial vs. generalized

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10
Q

What are the types of partial seizures?

A

Simple partial or Complex partial

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11
Q

If a patient has an abnormal jerky movement or stiffening of the body, or hear/smell/tastes things that are not there, and doesn’t not lose consciousness, what type of seizure is it?

A

Simple partial seizure

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12
Q

What are 2 other ways a simple partial seizure can present?

A

Autonomic – strange or unpleasant sensations in the stomach, chest, head, or heart rate

Psychic – garbled speech, deja-vu

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13
Q

Where is the brain is a simple partial seizure occurring?

A

ONE hemisphere

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14
Q

What are 3 variations of simple partial seizures?

A

Jacksonian March – motor activity begins distally (fingers) and spreads to the whole extremity

Todd’s Paralysis – local paralysis for minutes to hours

Epilepsia Partialis continua – continues for hours to days

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15
Q

If a patient has a continuous stare, but then doesn’t know what just happened for the past minute, what diagnosis are you thinking?

A

Complex partial seizure

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16
Q

Where does a complex partial seizure occur in the brain?

A

Start in the temporal lobe → then quickly involve other areas

17
Q

What often accompanies the complex partial seizure stare?

A

Usually an aura – but often isn’t noticed by the patient

Ictal stage – chewing or picking (very subtle)

Post-ictal confusion – impaired consciousness (can just last a few second to a few minutes)

18
Q

How do you diagnose a complex partial seizure?

19
Q

What differentiates a generalized seizure from a partial seizure?

A

Generalized = both hemispheres of the brain are firing simultaneously

Partial = a portion of the brain is firing

20
Q

So, what is it known as/what part of the brain is involved, if the seizure begins as a partial but then spreads and becomes more generalized?

A

Partial seizure with secondary generalization

Frontal lobe

21
Q

What is the key difference in a generalized seizure, and what are the two types?

A

Generalized seizures = sudden loss of consciousness

Either Convulsive (gran-mal or tonic clonic) or Nonconvulsive (petit-mal or absence)

22
Q

What form of a seizure is common in kids and often presents like daydreaming for less than 10 seconds?

A

Simple absence seizure

23
Q

What is a simple absence seizure lasted longer than 10 seconds?

A

Complex or atypical absence seizure

24
Q

What does an atypical absence seizure correlate with?

A

Mental retardation

25
What would you see on EEG with absence seizure?
Spike & wave that worsens with hyperventilation maneuver
26
If a patient collapses and tenses then begins to shake, what type of seizure is this?
Tonic-clonic or grand mal
27
Can a simple absence seizure be associated with tonic-clonic seizures?
YES
28
What are the characteristics of a tonic-clonic seizure?
Unconsciousness, post-ictal obtundation and confusion (for minutes to hours), sudden onset, and it might have a prodrome.
29
How would an EEG look during the tonic vs. clonic portions?
Tonic = increase in low voltage and fast activity; high amplitude polyspike discharges Clonic = spike & wave activity
30
What are the variations of the tonic-clonic seizures?
Atonic – 1-2 seconds lose motor tone, brief LOC, no post ictal confusion Myoclonic – brief contraction or jerk (like when you fall asleep)
31
What are 3 other types of generalized seizures?
juvenile myoclonic epilepsy Lenox gastaut syndrome Mesial temporal lobe epilepsy
32
What type of generalized seizure has partial epilepsy when an MRI shows hippocampal sclerosis?
Mesial temporal lobe epilepsy
33
What type of generalized seizure is seen in kids with EEG slowing, impaired cognitive function, and associated CNS disease?
Lennox gastaut syndrome
34
What type of generalized seizure is also seen in kids with a bilateral jerk with maintain consciousness, that’s worse with awakening/sleep deprivation?
Juvenile myoclonic epilepsy
35
In general, for seizures, what does treatment involve?
Basic life support – vitals & CPR Treat cause if identified (infection, tumor, drugs) Medications