seizures Flashcards

1
Q

key vital to take in seizure patients

A

BGL

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

when should midazolam be administer

A

Administer midazolam if the seizure is generalised and continues for longer than five minutes, or the patient has status epilepticus.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

IV midazolam

A

Administer midazolam IV:
a) 5 mg of midazolam IV for an adult. Reduce the dose to 3 mg if the patient is frail.
b) See the paediatric drug dose tables for a child.
c) This may be repeated once after five minutes.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

IM Midazolam

A

a) 10 mg of midazolam IM for an adult. Reduce the dose to 5 mg if the patient is frail.
b) See the paediatric drug dose tables for a child.
c) This may be repeated once after ten minutes

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

what to do if patient has own medication to stop seeing

A

Some patients have pre-prescribed medicines to be administered via the rectal, nasal or buccal route. All personnel may administer such medicines, even if not within their delegated scope of practice, provided they have been prescribed for that patient and the seizure continues for longer than five minutes, or the patient has status epilepticus.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

The patient may receive a clear recommendation not to be transported to a medical facility by ambulance, even if midazolam has been administered, provided the patient:

A

a) Has known epilepsy with no significant change in their usual pattern
seizures, or has recreational drug poisoning, and
Has not been injured, and

Has recovered to a safe postictal state, and
Can be left in the care of a competent adult,
and
Has received a maximum of one dose of parenteral midazolam by ambulance personnel,
and
Is instructed to see their GP within 72 hours for a review of their treatment

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

definition of status elepticus

A

ū Seizures that persist despite two doses of parenteral midazolam from clinical personnel, or
ū Three or more seizures with failure of the patient to have normal or purposeful movement between seizures.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

impact on the brain of of status elepticus

A

ū Prolonged and uncontrolled seizures alter brain receptor activity, making pharmacological control of seizures more difficult. The longer the seizures persist before being controlled, the more difficult control becomes.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

following the seizure you should…

A
  • Position the patient on their side.
  • Maintain airway and breathing.
  • Monitor pulse oximetry and administer oxygen if required.
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

seizure classification

A

generalised (grand mal) or partial (focal or localised).

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

Partial seizures may be….

A

simple (where the patient retains awareness of their surroundings) or complex (where the patient loses awareness of their surroundings).

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

Partial seizures may be….

A

simple (where the patient retains awareness of their surroundings) or complex (where the patient loses awareness of their surroundings).

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

A patient having partial seizures may present

A

without obvious convulsions or motor activity and may be able to obey commands and interact during seizure activity. The patient may present with any combination of the following:
ū Habitual repetitive movements (automatisms).
ū Sensory symptoms including visual or auditory hallucinations.
ū Emotional outbursts or unusual feelings, such as feeling like they are
outside their body.
ū Blank gaze.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

Non-epileptic seizures occur when there

A

is motor activity that looks clinically like seizures, but there is no electroencephalography (EEG) evidence of seizure activity in the brain.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

how to draw up midazolam for a Pead

A

Midazolam IV 1 mg/ml
* Draw up 1 ml of midazolam from a 15 mg/3 ml ampoule.
* Dilute to a total volume of 5 ml using 0.9% sodium chloride.
* Discard unrequired drug and administer the volume from the tables as an IV bolus.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

1

A

1

17
Q

mechnism of midaz

A
  • Midazolam is a benzodiazepine.
  • Midazolam enhances the activity of gamma-aminobutyric acid (GABA) at GABA receptors within the central nervous system, resulting in anticonvulsant activity, sedation, amnesia, anxiolysis and muscle relaxation.
18
Q

IV admin of midaz

A
  • IV administration:
    a) Dilute 2 ml from a 15 mg/3 ml ampoule to a total of 10 ml using 0.9% sodium chloride. This solution contains 1 mg/ml.
    b) Administer IV as a bolus.
19
Q

IM admin of midaz

A

IM administration:
a) Draw up the dose from a 15 mg/3 ml ampoule. Do not dilute.
b) The preferred site is the lateral thigh as this has the best absorption. If this
site is not suitable use the lateral upper arm.
* For sedation post intubation: combine 10 mg of midazolam with 100 mcg of fentanyl and dilute to a total of 10 ml using 0.9% sodium chloride.

20
Q

common adverse affects off midaz

A

Common adverse effects
* Sedation.
* Respiratory depression.
* Hypotension.
* Amnesia.

21
Q

onset and duration of midaz

A

Usual onset of effect
* IV: 2-3 minutes.
* IM: 3-5 minutes.
Usual duration of effect
* 30-60 minutes. The sedative effect may be longer, particularly in the elderly.

22
Q

ADD NEW DRUG LEVE

A
23
Q

if the seizure continues or recurs after two parenteral doses of midazolam what should be done next

A

Administer levetiracetam IV if the seizure continues or recurs after two parenteral doses of midazolam:
2 g of levetiracetam for an adult.
See the paediatric drug dose tables for a child.
Repeat once after ten minutes for an adult, if the seizure continues or recurs ten minutes after the first dose.
Consider performing RSI if the seizure continues.

24
Q
A
25
Q

why is status elepticus life threatening

A

ū Status epilepticus is life-threatening because it is commonly associated with hypoxia, hypercarbia, metabolic acidosis (lactate is produced during vigorous skeletal muscle activity), hyperthermia (as a result of prolonged muscle activity) and aspiration.
ū RSI may be required.
ū General anaesthesia and admission to an intensive care unit is often
required.

26
Q
A