Seizure disorders Flashcards

1
Q

Epilepsy is

A

Any disorder with recurrent unprovoked seizures.

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2
Q

Classification of seizures:

A

Focal

Generalized

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3
Q

Focal seizure involves

A

Involve a region or part of the brain

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4
Q

Generalize seizure is

A

A seizure that can not be classified.

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5
Q

2 types of Focal seizure:

A
  1. With out impairment of consciousness.

2. With impairment of consciousness.

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6
Q

What is diagnostic of Epilepsy

A
  1. Recurrent seizure activity
  2. Charters it’s ECG changes with seizures
  3. Mental status abnormalities
  4. Focal neurological symptoms persist postictally.
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7
Q

Mess that lower seizure threshold

A
Quinolone so
Cephalosporins
Antipsychotics
Wellbutrin
TCAs
Fentanyl/Demerol
Theophylline 
Cocaine /Amphetaines
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8
Q

Seizure medications
Side effects
Lyrica( Pregabalin)

A

Dizziness
Some lance
Ataxia

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9
Q

Seizure medication
Side effects
Regretful

A
Diplopia
Dizziness
APLASTIC ANEMIA
StevenJohnson Syndrome
Toxic epidermal necrosis
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10
Q

Seizure medication

Side effects Lamictal ( Lamotrigine)

A

Diplopoda
Dizziness
Unsteadiness

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11
Q

What is first line therapy for newly diagnosed partial seizures

A

Tegeretal ( Carbamazpine)

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12
Q

What is second line therapy for partial seizures who failed initial therapy?

A

Taiga binge

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13
Q

Seizure medication

Side effects of Keppra ( Levetiracetam)

A

Aggression
Sedation
Fatigue
Decreased coordination

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14
Q

Seizure medication
Side effects
Lacosamide ( Vimpat)

A

Dizziness, Diplopoda, ataxia, N/V,

Nystagmus

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15
Q

What is a seizure

A

Temp Alteration in brain function d/t excessive synchronization neuronal activity that results in body movements, sensations and altered consciousness

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16
Q

Define Epilepsy

A

Chronic condition characterized by 2 or more unprovoked seizures.

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17
Q

Classification of seizure

Partial Seizure

A

Simple

Complex

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18
Q

Classification of Generalized

A

Absence
Myoclonic
Tonic-clinic

19
Q

Presentation of a Partial seizure

Simple Partial No LOC

A

Focal motor
Focal sensory
Autonomic
Deja vue, fear, gastric rising

20
Q

Presentation of a Partial Seizure

Complex Partial

A

Alteration of consciousness

Confusion to obtundant

21
Q

Presentation of a Generalized Seizure

Absence:

A

Brief impairment of consciousness ( 10-40 Sec)
Automatisms
Autonomic events
Amnestic to the event

22
Q

Presentation of a Generalized

Myoclonus epilepsy:

A

Sudden electric like jerking

23
Q

Presentation of a Generalized

GTC:

A
Tonic phase
Abrupt LOC W/O warning, 
Rigidity
Often vocalized
Resp arrest
Progress to a clonic phase
Rhythmic jerking of body postictal confusion
24
Q

Presentation of PNES

A
Vary each spell
Typically eyes are closed
Prolonged
Suggestible
Asymmetric 
Asynchronous movement 
Variation in freq and amplitude
25
Q

PNES is a manifestation of

A

Psychiatric distress

26
Q

What does PNES mean

A

Psychogenic
Non-Epileptic
Spells

27
Q

Seizure provoking factors

A
Increased or decreased glucose
Decreased ammonia 
Decreased Na++
Hypoxia
ETOH
28
Q

Seizure provoking Illegal drugs

A

Amphetamine

Cocaine

29
Q

Seizure provoking can be brought about from abrupt withdrawal of

A

Barbiturates
Bentos
ETOH

30
Q

What medications can provoke Seizure

A

Bentos
AEDs
Cipro

31
Q

Seizure medication

Side effects of Depacote ( Valporic Acid)

A

BLACK BOX WARNING:
Hepatotoxicity in children
Teratogen ( malformation of a embryo)

32
Q

Seizure medication side effect

Dilantin ( Phenytoin)

A

Cardiovascular risk with rapid infusion
Gingival hyperplasia
RASH
Vit d deficiency

33
Q

Seizure medication side effects

Neurontin ( Gbapentin )

A

Fatigue
Somnolence
Dizziness
Ataxia

34
Q

Which medication is first line therapy for

Primary generalize seizures

A

Depakote

35
Q

What I’d first line therapy for
Primary Generalized
Convulsive
And partial seizures

A

Dilantin ( Phenytoin)

36
Q

What is a second line medication for partial seizures who failed initial treatment

A

Neurontin ( Gabapentin)

37
Q

What is the medical monitoring for a patient with seizure disorder

A

Drug levels for compliance
CBC
LFTs

38
Q

When can a person with a seizure history drive in OHIO

A

3 months of being seizure free.

39
Q

What is the leading cause of death in Epilepsy

A

SUEP with uncontrolled Epilepsy

40
Q

What does SUDEP stand for

A

Sudden Unexpected Death in Epilepsy

41
Q

What is Status Epilepticus

A

Persistent seizure for > 30 mins

42
Q

A seizure that last more than 5 mins should be treated as

A

Status

43
Q

What’s the number one reason for Status Epilepticus

A

Non adherence to medication regime or

Abrupt discontinuation of medication