Seizure Flashcards

1
Q

Define seizure

A

A chronic disease involving periodic sudden bursts of the brain
-may be a symptom of other health disease

Can be
Conclusive / non-conclusive
frequency / severity

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2
Q

May affect

A

-muscle control
-speech
-vision
-awareness

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3
Q

Convulsion definition

A

Sudden attack of involuntary muscular
contractions and relaxations

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4
Q

Epilepsy

A

-chronic ongoing series of seizures
A group of recurrent disorders of cerebral function characterized by both seizures and convulsions

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5
Q

Description of epilepsy

A

-occur at any age
-neurological disorder
-can be called seizure disorder
-Seizures are chronic, ongoing

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6
Q

Why do seizures occur ?

A

-head injury
-intracerebral injuries
-heredity
-metabolic disorders
-fever
-birth injury
-congenital disorders
-infection

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7
Q

Causes of triggers

A

-missed dose of medication
-illness
-stress
-dehydration
-flashing lights

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8
Q

Signs of seizures

A

-headaches
-periods of forgetfulness
-falling
-jerking movements
-feel out of body
-unusual smells

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9
Q

Types of seizures

A

Focal
-Occurs in part of the brain ( simple partial, complex partial)

Generalized
-in whole brain (tonic, atonic, tonic-clonic, myoclonic, absence)

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10
Q

Pathophysiology

A

Characteristic
-brought by abnormal electric activity of the brain

Type
-absence (mild episodes / petit mal)
-major tonic clinic (grand mal)

Duration
-1-2 period of disorientation

Causes
-may be a result of tumor, injury or neurological disease

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11
Q

Diagnosis

A

-Electroencephalography (EEG) studies
reveal abnormalities in brain activity and can be used in diagnosis and treatment of epilepsy.
-history / physical examination
-imaging (CT/MRI/PET)

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12
Q

Define Neurotransmitters

A

Small molecules used by neurons to communicate among themselves

-regulate electrical activity of a given neurons and tell where to fire an action potential or when not to

-glutamate (exctory / tell neurons to fire)
-GABA (inhibitory / dampens neuron firing rate)

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13
Q

Stages of seizures

A
  1. Aura stage
    -hallucinations
    -dizzy
    -distorted emotions
    -confusion
  2. Tonic stage
    -back arched
    -stiff body
    -epileptic cry
  3. Clonic stage
    -jerky movements
    -frothy saliva
    -blinking eyes
  4. Postical stage
    -weak limbs
    -exhaustion
    -sleepy
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14
Q

Signs of seizures

A

-extended blank stare
-eyes rolling upward
-unresponsiveness
-uncontrollably jerking body movements
-loss consciousness
-frothing at mouth

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15
Q

Types of seizure

A

•Partial (Focal) seizures
-excessive electrical activity in one Cerebral hemisphere / affects only part of the body
1)simple partial (may experience a range of strange or unusual sensations)
-motor, sensory, autonomic, preservation of consciousness

2)complex partial
-loss of awareness, originate in frontal or temporal lobes eg: temporal lobe epilepsy

•Generalized seizures
-excessive electrical activity in both cerebral hemispheres
-originates in thalamus / brainstorm
-affects the whole body
-loss of consciousness
-myoclonic (brief shock-like muscle perks generalized / restricted to part one extremity)
-atonic (sudden loss of muscle tone)
-tonic seizures (sudden stiffen of the body, arms, legs)
-clonic seizures (rhythmic perking movements of the arms and legs without a tonic component)
-tonic-clonic ‘grand mal (tonic phase followed by clonic phase)
-absence ‘petit mal (person blank out)
-lenox-glastaut syndrome (Atypical absence, tonic and myclonic)
-status epilepticus (seizure last long than 30min)

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16
Q

Antiseizure drugs

A

•suppress / prevent abnormal or repetitivefiring

Groups:
-barbiturates
-benzodiazepines
-hydantoins
-phenytoin-like agents (most used)
-succinimides

17
Q

Anticonsulvants mechanism of action

A

-enhancement of GABA actions
-Vigabatrin (increase brain GABA levels and GABA release)
-Tiagabine (inhibits reuptake of GABA by increasing the amount of GABA in synaptic cleft)
-Benzodiazepines and phenobarbital (increase central inhibitionbybenhance action of synaptic released GABA at the GABA receptor)

18
Q

Stimulating an influx of chloride ions

A

-gamma-aminobutyric acid (GABA) is the inhibitory neurotransmitter in brain
-when the receptor is stimulated, chloride ions move into the cell, suppressing ability of neurons to fire
-antiseizure drugs act by mimic the effects of GABA by stimulate GABA receptor

19
Q

BCECTS / Benign rolandic epilepsy

A

-genetic
-onset from 1 to 15yrs
-prevelance 15 to 25% of children with seizure
-typical seizures- hemifacial paresthesia, motor seizures with speech arrest, drooling
-easily controlled with treatment