Seisure Disorders

Question 1

Side effects of Hydantoins- phenytoin, ethotoin, fosphenytoin (4)

Answer 1

Mild drowsiness and other cns effects;
Gingival hyperplasia
Skin rash
Withdrawal symptoms

Question 2

Normal hydantoin levels

Answer 2

10-20mcg/ml

Question 3

monitor these side effects of toxicity due to hydantoin (5)

Answer 3

nystagmus
ataxia
sedation
blurred vision
double vision

Question 4

IV rate admin for hydantoin should be less than x mg/min

Answer 4

50

Question 5

contraindications of hydantoins (6)

Answer 5

pregnancy D
bradycardia
heart block
seisure dt low blood sugar
previous allergies
skin rash

Question 6

cautious use of hydantoins in these (8)

Answer 6

resp dysfx
cardiac dysfx
liver dysfx
kidney dysfx
diabetes
older
debilitated
alcoholics

Question 7

this substance can increase or decrease level of hydantoins

Answer 7

alcohol

Question 8

can decrease hydantoin levels (2)

Answer 8

phenobarbital

carbamazepine

Question 9

prototype hydantoin drugs (3)

Answer 9

phenytoin
ethotoin
fosphenytoin

Question 10

phenytoin brand name

Answer 10

Dilantin

Question 11

ethotoin brand name

Answer 11

Peganon

Question 12

fosphenytoin brand name

Answer 12

Cerebyx

Question 13

types of cns depressants for treating grand mal or tonic-clonic and partial seisures

Answer 13

hydantoins

Question 14

examples of hydantoins (3)

Answer 14

phenytoin
ethotoin
fosphenytoin

Question 15

Three main types of drugs for treating seisure disorders

Answer 15

hydantoins- phenytoins, ethotoins, fosphenytoin
iminolstilbenes- carbamazepine
valproic acid

Question 16

valproic acid brand names (3)

Answer 16

Depakote
Depakene
Depacon

Question 17

valproic acid prevents seisures by inhibiting these (3)

Answer 17

sodium
calcium
gaba

Question 18

iminostilbenes prevent seizures by inhibiting the influx of (1)

Answer 18

sodium

Question 19

hydantoins prevent seizures by inhibiting the influx of (1)

Answer 19

sodium

Question 20

adverse CNS effects of iminostilbenes (4)

Answer 20

headaches
ataxia
nystagmus
blurred vision

Question 21

lower dose of aminostilbenes if levels of this (1) is below 3000 per mm3, due to (1)

Answer 21

wbc

Question 22

risk factors steven johnson’s syndrome (6) main and name specifics

Answer 22

medications (antiseasures, pain meds, antipsychotics, radiation)
viral infection (viral, hiv, hepatitis, viral pneumonia)
specific gene (HLA-B 1502) mostly in asian descent
immunosuppressed (HIV, lupus, transplants)
history of sjs
fam history

Question 23

pain meds that can cause steven johnson’s syndrome (3)

Answer 23

ibuprofen, acetaminophen, naproxene sodium

Question 24

viral illness that can cause steven johnson’s syndrome (5)

Answer 24

hepatitis
viral infection
viral pneumonia
HIV
herpes

Question 25

meds that can cause steven johnson's syndrome (6)

Answer 25

``` anti-seisures pain meds antipsychotics carbamazepine anticonvulsants radiation antibiotics ```

Question 26

sjs primarily affect these organs in the body (2)

Answer 26

the skin and mucus membrane

Question 27

the initial nonspecific presentation of sjs (6)

Answer 27

``` flu like symptoms sore throat sore mouth cough fatigue burning eyes ```

Question 28

blister develop in mucous membranes in these areas in sjs (4)

Answer 28

mouth nose eyes genitals

Question 29

symptoms of sjs (7)

Answer 29

``` red/purple rash blisters in mouth, nose, eyes, genitals facial swelling tongue swelling hives skin hives skin pain ```

Question 30

health promo re sjs (5)

Answer 30

``` genetic testing for gene HLA-B 1502 in asians inform md if previous reaction to med know what med/condition causes reaction avoid med that triggers medic alert bracelet ```

Question 31

action of iminostilbenes carbamazepine

Answer 31

decreases neuron discharge t