Antidepressants

Question 1

side effects of tricyclics (amitryptiline, imipramine, nortriptyline, amoxapine, trimipramine) (8)

Answer 1

• drowsiness
• sedation
• anticholinergic effects (blurred vision, dry mouth, urine retention, constipation)
• tachycardia
• orthostatic hypotension
• increased suicide risk
• high risk for overdose
• withdrawal symptoms with abrupt discontinued (headache, anxiety, weakness, nausea, muscle pain)

Question 2

withdrawal symptoms of tricyclics (5)

Answer 2

headache
anxiety
muscle weakness
nausea
muscle pain

Question 3

treatment for overdose of tca/ tricyclics

Answer 3

gastric lavage
physostigmine
lidocaine for dysrhythmics

Question 4

full therapeutic effect of tca?

Answer 4

1-3 weeks

Question 5

best time to take tca?

Answer 5

bedtime