Section C - 12. 8, 9, 10, 11 Flashcards
The aorta and other systemic arteries have ___ walls containing ___ quantities of ___ tissue
thick, large, elastic
Compliance =
= DeltaVolume/DeltaPressure
Max arterial pressure reached during peak ventricular ejection is called ___
Systolic pressure (SP)
Minimal arterial pressure, just before ventricular ejection begins, called ___
Diastolic pressure (DP)
Pressure over time graph
Diastolic pressure –> systolic pressure –> aortic valve closure –> mean pressure
Pulse pressure
the difference between SP and DP
MAP formula
Diastolic pressure plus one third of the pulse pressure
___ ___ can be heard through a stethoscope when high velocity blood flow is turbulent and creates vibrations
Korotkoff’s sounds
Functions of arterioles
- responsible for determining the relative blood flows to organs at any given MAP, 2. major factor in determining MAP itself
Flow through any organ. =
Forgan = (MAP - Venous pressure)/Resistanceorgan
Spontaneous contractile activity in arteriolar smooth muscle
intrinsic tone
Hyperemia
increased blood flow
Active hyperemia
Incr blood flow during incr metabolic activity, the direct result of arteriolar dilation in the more active organ/tissue
Nitric oxide
gas released by endothelial cells, which acts on the immediately adjacent vascular smooth muscle
Flow autoregulation
Change in resistance is in the direction of maintaining blood flow nearly constant despite the pressure change
Myogenic responses
direct responses of arteriolar smooth muscle to stretch
Reactive hyperemia
when an organ/tissue has had its blood supply occluded, and a transient increase in its blood flow occurs if flow is reestablished (ex: taking off tight bandaid)
Neurons release ___ which binds to ___ receptors on the vascular smooth muscle to cause ___
norepinephrine, a-adrenergic, vasoconstriction
The majority receive parasympathetic or sympathetic input?
sympathetic
the hormone ___ constricts most arterioles
angiotensin II
___ is released into the blood by the posterior pituitary in response to a decrease in blood pressure, and causes arteriolar constriction
Vasopressin
the hormone secreted by the cardiac atria, ___ ___ ___, is a vasodilator
atrial natriuretic peptide
___ ___ is a ___ vasodilator secreted by endothelial cells
nitric oxide, paracrine
at any given moment, _% of total circulating blood is flowing through capillaries
5%