Module A - 12.1, 12.2 Flashcards
Erythrocytes
Red blood cells
Leukocytes
White blood cells
Erythrocyte function
Carry oxygen to tissues and carbon dioxide from tissues
Leukocyte function
Protect against infection, cancer, platelets function in blood clotting
Hematocrit
% of blood volume that is erythrocytes
Groups of plasma proteins (3)
Albumins, globulins, fibrinogen
Serum
Plasma w/ fibrinogen
All blood cells are descendent from a single population of cells called _____ _____ _____ _____
Multipotent hematopoietic stem cells
Oxygen and carbon dioxide reversibly combine with _____
Hemoglobin
Site of erythrocyte production
Red bone marrow
Reticulocyte
Ribosomes contained by young erythrocytes, producing a reticular appearance when treated w special stains
Major breakdown product of hemoglobin
Bilirubin
Lifespan of erythrocyte
120 days
Element to which oxygen binds on a hemoglobin molecule within an erythrocyte
Iron
Excess of iron
Hemochromatosis
Iron is bound up in a protein called ___
Ferritin
About __% of the total body iron is in hemoglobin, __% heme containing proteins and __% ferritin
50, 25, 25
Old erythrocytes are destroyed and the iron is bound to ___
Transferring
Absorption of B12 requires a protein called ___ ____
intrinsic factor
Erythrocyte production is called ____
Erythropoiesis
Erythrocyte production is exerted by a hormone called ____
Erythropoietin
EPO acts on the ____ _____
Bone marrow
Scenarios with higher EPO secretion
Insufficient pumping of blood by heart, lung disease, anemia, prolonged exercise, high altitude
Increase in EPO secretion results increased…
EPO secretion, plasma EPO concentration, erythrocyte production, oxygen carrying capacity of the blood
Higher hematocrit in men is due to..
Testosterone stimulates the release of EPO
Condition in which there are more erythrocytes than normal
Polycythemia