Section 8: Digestive System Flashcards
Gut - structure
A soft muscular tube
~5m long
Gut - function
Where food is stored, broken down and absorbed
Glands associated with gut tube
Pancreas
Liver
Tooth: Enamel
Crystalline rods/prisms of calcium phosphate and carbonate
No cells –> difficult to replace
No sensation
What is the hardest tissue of the body
Enamel of teeth
Tooth: Dentin
Similar to bone, but cells (odontoblasts) are localised at junction between dentin and pulp instead of scattered
Tooth: Pulp
Core of tooth
Soft tissue
BVs, nerves, lymphatics
Tooth: Cementum
Calcified CT surrounding dentin in root region
Tooth: Periodontal ligament
Collagen fibres linking alveolar bone to cementum
Rapid turnover
Tooth: Alveolar bone
Bone of the socket
Tooth: Enamel - what does it cover
Covers dentin in the crown region
Tooth: Periodontal ligament - size
Short in terms of distance, but has large X-sectional area
So distance between cementum and alveolar bone is v short
Tooth: Periodontal ligament - mechanoreceptors - functions
Protection, e.g. biting a fork
Force transducers, e.g. braces
Tooth: Periodontal ligament - rapid turnover
Lots of collagen synthesis
Vit C is crucial for this, so a poor vit C supply –> scurvy –> teeth can fall out
Tooth: Why is it important to remove infections in the pulp
Because there’s a blood supply there –> bacteria can travel into blood vessel
How many roots do most teeth have
3-4
Tongue has both _____ and ______ muscles
Intrinsic
Extrinsic
Tongue: Intrinsic muscles
Longitudinal - along length of tongue
Vertical
Horizontal/transverse
Tongue: Intrinsic muscles - contraction
Longitudinal - shortens tongue
Vertical - flattens tongue
Horizontal/transverse - narrows tongue
Tongue: Papillae
Projections towards surface of tongue
Tongue: Papillae - types
Filiform
Fungiform
Vallate
Tongue: Papillae - filiform
Sharp-like
No taste buds
Flexible
Tongue: What is the most common form of papillae
Filiform
Tongue: Papillae - fungiform
Mushroom-like projections
Some have taste buds but not many
Tongue: Papillae - vallate
Most important for taste buds
Surrounded by a groove like a moat - protection
Tongue: Papillae - different regions
Depending on the region of tongue, have diff frequencies of types of papillae
Salivary glands - major types
Parotid - serous only
Sublingual - mixed, mostly mucous
Submandibular - mixed
Salivary glands: Types of cells
Serous cells (watery) Mucous cells (viscous)
Salivary glands: Serous cells
Contribute a watery component towards saliva that is enzyme-rich
Salivary glands: Serous cells - enzymes
Amylase
Lysozyme
Salivary glands: Enzymes - amylase
Breaks down carbohydrate/starchy debris around teeth
Contained within zymogen granules and released in batches when you chew food to make sure there’s not abundant starch for bacterial growth
Salivary glands: Enzymes - lysozyme
Antibacterial properties
Salivary glands: Mucous cells
Viscous/sticky
Good for lubricating
Contain mucin granules
Salivary glands: Types of cells - staining
Serous cells = quite dark-staining
Mucous cells = quite light-staining
Salivary glands: Parotid glands - location
In front of ears
Digestive system - functions
Digestion
Absorption
Secretion
Transport
Digestive system: Functions - digestion
Chemical breakdown of ingested food into absorbable molecules
Requires secretion
Digestive system: Functions - absorption
Movement of nutrients, water and electrolytes through epithelial lining of gut into blood or lymph
Digestive system: Functions - secretion
Saliva - enzymes and mucous
Gaining surface area - methods
Gross convolutions
Luminal folds/wrinkles
Projections towards lumen = evagination
Projections away from lumen = glands
Gaining surface area: Luminal folds - examples
Circular in small intestine = plicae circulares
Longitudinal, e.g. stomach = rugae
Gaining surface area: Evagination - examples
Villus/villi, small intestine
Gaining surface area: Glands - examples
Stomach and small intestine
Gaining surface area - must take what into account?
Time
Tunics of gut tube - what are they
Mucosa (mucous membrane)
Submucosa
Muscularis externa (external smooth muscle)
Serosa
Tunics of gut tube: Mucosa - components
Epithelium
Lamina propria
Muscularis mucosae
Tunics of gut tube: Mucosa - epithelium
Specialised for protection, absorption, secretion, or combination of all 3
Physical barrier between outside world and internal systems
What happens if there’s a breach of the epithelium
Results in ulceration
Tunics of gut tube: Mucosa - lamina propria
Soft fibrous bed of loose CT where the epithelium rests
Carries nerves and blood capillaries
Populated with defense cells and collagen
Support
Tunics of gut tube: Mucosa - lamina propria - lymphocytes
Scattered throughout gut to control pathogens / harmful agents coming through
Tunics of gut tube: Mucosa - muscularis mucosae
2 thin layers of smooth muscle; inner circular and outer longitudinal
Provides mucosa with some movement independent of external muscle coat
Tunics of gut tube: Submucosa
Thick bed of loose CT carrying larger BVs, lymphatic vessels and nerves (submucosal plexus)
Connects mucosa to external muscle coat, but allows some movement between them
Tunics of gut tube: Muscularis externa
2 layers to produce peristalsis (transport)
Inner circular layer and outer longitudinal layer
Tunics of gut tube: Muscularis externa - myenteric nerve plexus
Occurs between the two layers of the muscularis externa
Responsible for coordinating the 2 layers
Enteric nervous system is made up of…
Submucosal nerve plexus + myenteric nerve plexus
Enteric nervous system: SNS and PNS
PNS excites/stimulates enteric NS
SNS inhibits function of enteric NS
Enteric nervous system and ANS
Enteric NS is thought of as a separate entity, but has many interactions with ANS
Tunics of gut tube: Serosa
A slippery outer covering for gut tube (except oesophagus)
Tunics of gut tube: Serosa - layers
Two layered;
Outer mesothelial boundary
CT layer
Tunics of gut tube: Serosa - AKA…
Visceral peritoneum
Tunics of gut tube: Serosa - adventia
Where a structure is not in contact with the body cavity, the outermost CT layer is referred to as the adventitia
Mesothelial cells secrete…
Serous fluid
Oesophagus - structure
Muscular tube
Extends from pharynx to stomach
Normally empty with lumen collapsed, and expands to accommodate food/water
Oesophagus - functions
Transport (fast travel time, due to peristalsis)
Protection
No absorption or digestion, little secretion
Oesophagus: Epithelium
Thick, stratified squamous, with sacrificial outer layers for protection against abrasive fragments of food
Protects against friction and abrasion
Oesophagus: Epithelium - how are cells replaced
By division in basal layers at BM, then slow migration outwards
Oesophagus: The entire epithelium is renewed every ______
7 days
What is the most variable throughout the gut tube
Epithelium
Serosa vs adventitia
Serosa: when an organ is not in contact with a neighbouring organ, and instead is in contact with a body cavity
Adventitia: glues one organ to its adjacent organs
Omentum
A fatty apron-like structure that hangs off the transverse colon
Must cut this away to expose underlying organs
Fatty tissue - function
Protection
Omentum - lymphatic tissue
Helps control localised infection by migrating to quarantine the infection
Swallowing food - pathway
Food is pushed backwards by tongue –> oropharynx –> laryngopharynx –> oesophagus
Swallowing food - epiglottis
Bolus comes in contact with epiglottis, pushing it backward to seal off the glottis (opening to trachea)
Adventitia between trachea and cartilage
Loose because it needs to move/expand
Oesophagus - luminal surface
Many layers of stratified squamous epithelium
Tunics of gut tube: Mucosa - lamina propria - blood vessels
Supply epithelium with nutrients and O2, and take waste away from epithelium
Oesophagus: External muscle (Muscularis externa)
Contains additional skeletal muscle in upper third of oesophagus to allow rapid contraction and voluntary control of swallowing
Oesophagus: Serosa
Majority of oesophagus doesn’t lie in a body cavity so lacks a serosa
Instead is mostly covered with a fibrous adventitia
Only when it passes the diaphragm into abdominal cavity where it starts to have serosa
Bolus of food travels down the oesophagus by _____
Peristalsis
Oesophagus: Peristalsis
Involves coordinated contraction of inner circular and outer longitudinal muscle layers (muscularis externa)
Inner = narrows tube
Outer = shortens tube –> squeezing motion
Stomach - structure
J-shaped bag on left side
Enlargement of gut tube