Labs Flashcards
Rats - teeth
Dentition adapted for gnawing Paired incisors grow throughout life and lack enamel on their posterior surfaces --> rapidly wears --> characteristic chisel-shape Lower jaw (mandible) is in 2 pieces, hinged in the middle Space between incisors can be varied at will
Rats - gall bladder
Absent in rats
Rats - reproductive system vs in humans
Rats:
Female - uterus is Y-shaped
Male - penis mostly within abdominal wall
Humans:
Female - uterus is pear-shaped
Rats - nostrils/nares
May be closed under water
Rats - identifying male vs female
Male:
Scrotum (which contains testes) will be seen near anus
Anterior to scrotum is prepuce (skin fold concealing glans of penis)
Flaccid penis contained within abdominal wall
Female:
Three openings - anus, vaginal opening, urethral opening
Rats - thymus gland is _____ to the heart
Anterior
Rats - when making the first cut and you hit resistance, what have you reached
The diaphragm
Exposes abdominal cavity - not thoraric cavity, which lies anterior to diaphragm and beneath rib cage
Rats - peritoneum
A wet, slippery, thin membrane bonded to the abdominal wall
Surrounds the peritoneal cavity
Rats - Parietal peritoneum, visceral peritoneum and mesentery
Parietal peritoneum (lining abdominal wall) continuous with mesentery (double layer of peritoneum suspending intestine), further continuous with visceral peritoneum (covering intestine)
Rats - ventral cavities
Two pleural cavities (lung)
Pericardial cavity (heart
Peritoneal cavity
Humans vs rats - pericardium
Much thicker, stronger and fibrous in humans
Rats - What are organs wrapped in?
Serous membrane
Rats - Serous fluid
Allows organs to move over each other easily
Rats - parietal vs visceral peritoneum
Parietal: attached to skin
Visceral: attached to organs
Humans - order of digestion
Oesophagus (tube) Stomach (bag) Small intestine (tube) Caecum (bag) Sigmoid colon (tube)
Rats - liver
Large gland
Has both exocrine and endocrine functions
Highly vascularised
Rats - lung colour
Since killed humanely with CO2(g), lungs will appear dark red and blood-filled (haemorrhage)
Normally is a bright pink colour and spongy texture
Rats - heart
Anterior end (‘base’) is overlapped by 2 lobes of the thymus gland
Rats - why is the gut tube convoluted
So it is long, to gain increased SA for absorption and secretion
Rats: Gut - portions
3 tubular portions: oesophagus, small intestine, large intestine
2 sacs: stomach and caecum
Rats: Where do absorption and secretion occur in gut
Everywhere downstream of oesophagus
Secretion occurs in 2 large glands (liver and pancreas) which are derived embryologically from gut lining and shed their secretions into small intestine
Humans and rats: Where is the stomach located
Lies mostly on the left side
Rats: Stomach - greater and lesser curvature
Oesophagus enters part-way along the lesser curvature (from throat through thoraric cavity, dorsal to heart and lungs, to diaphragm)
Rats: Lining of stomach
Divided into 2 distinct types
Anterior and lateral portion:
Has a thin and translucent wall so gut contents often visible
Specialised for food storage
Lining resembles that of oesophagus - no glands and a protective stratified squamous epithelium
Human stomach doesn’t have such a glandless portion compared to rat
Pyloric region (medial and posterior): Glandular and opaque Numerous simple tubular glands release acids and enzymes which break large molecules down (digestion)
Rats: Stomach - pyloric sphincter
Constriction at outlet of stomach
A collar of smooth muscle which controls flow of stomach contents (chyme) into the duodenum
Rats: Small intestine - structure
Rosette structure
Tube of uniform diameter, about 4 body-lengths from inlet to outlet
Irregularly coiled to allow it to fit within abdomen
Attached to dorsal body wall by a transparent mesentery / double layer of peritoneum
Rats: Small intestine - main function
Absorption of small molecules resulting from digestion
Rats: Small intestine - regions
Duodenum (leaving stomach)
Jejunum
Ileum (entering caecum)
Rats: Small intestine - blood vessels
Often shrouded with fat
Fan out through mesentery to supply and drain intestinal wall
Rats: Pancreas - endocrine or exocrine?
Both
Gland releases an alkaline digestive juice containing enzymes into duodenum
Also contains endocrine cells which secrete hormones into bloodstream
Humans vs rats: Pancreas
Both sit close to the greater curvature of stomach
Rat pancreas is a more diffuse organ than human pancreas
Rats: Pancreas - appearance
Made up of small, scattered pink lobules suspended by mesentery
What is the largest gland in the body
Liver
Rats: Liver - function
Both endocrine and exocrine
Performs numerous functions concerned with metabolic regulation and produces bile (bi-product) which contains mainly excretory products
Rats: Liver - bile salts
Aid in digestion and absorption of fats and vitamins
Humans vs rats: Where is bile stored
Humans and other mammals: stored in a gall bladder whose duct joins the bile duct to discharge into the duodenum
Rats: lack a gall bladder, but like humans, pancreatic ducts join hepatic duct to discharge into the duodenum, a short distance downstream of the pyloric sphincter
Rats: Liver - structure
Large size
About 4 lobes
Dark red colour - rich blood supply (vascular)
CT capsule is very thin
Soft, jelly-like texture
Vulnerable to traumatic injury –> severe internal bleeding
Rats: Liver - receiving blood
Receives venous blood from gut wall (via hepatic portal vein)
Receives oxygenated blood from aorta (via hepatic artery)
Rats: Spleen - which system is it part of
NOT part of digestive system
Part of lymphatic system
Rats: Spleen - structure
Dark red
Elongated
Leaf-shaped
Humans vs rats: Spleen
Human spleen more compact than in rat, since it is fist-shaped instead of leaf-shaped
Sits in same position
Rats - appendix
No appendix
Rats: Large intestine - parts
Caecum
Colon
Rectum
Anus
Rats: Large intestine - function
Reabsorption of water
Formation of faeces from undigested food residue
Rats: Large intestine - faeces
Resident bacteria contribute to putrification of faeces
Retained in rectum
Voided periodically through anus
Rats: Caecum - structure
Flabby, thin-walled bag
Contains poop
Humans: Terminates in a vermiform appendix containing lymphoid tissue
Rats: Lack a true vermiform appendix
Rats: Caecum - function
Bacteria act on gut contents while they are slow-moving
Rats: Colon - parts
Ascending (anteriorly) on right
Transverse
Descending (posteriorly) on left towards rectum
Quite untidy arc, much less geometric than human colon
Rats: Colon - firmness
Colonic contents upstream are semi-fluid, but downstream are formed into more or less firm faeces
Rats: Rectum
Short passage leading to anal outlet
Only visible after extensive dissection
Rats: Anus
A sphincter under partial voluntary control
Allows faeces to be voided
Rats: Kidneys - structure
Buried in fat on dorsal wall of abdominal cavity
Ventral surface: covered with parietal peritoneum
Dorsal surface: attached to body wall
Said to be retroperitoneal (behind the peritoneum)
Dark red - rich blood supply
Rats: Kidneys - hilus/depression on medial surface
Point where renal artery, renal vein and ureter access kidney
Rats: Adrenal glands
Small brown bodies embedded in fat near anterior pole of kidneys
Outer crust/cortex: secretes steroid hormones
Inner core (medulla): secretes adrenalin
Rats: Urinary bladder
Midline near pelvis
Pale cream or yellow in colour
Varying in size depending empty or full
Rats: Male reproductive organs - reproductive glands
Seminal vesicles
Prostate gland
Rats: Female reproductive organs - horns
At distal end of each horn is a small dark-coloured ovary which connects via a tightly-coiled oviduct
Oviduct so small it’s difficult to distinguish from ovary
Rats: Female reproductive organs - why is uterus Y-shaped
Multiple babies
Rats: Mouth and pharyx - breathing vs swallowing
Breathing: air must transit from nasal passages to trachea
Swallowing: food must transit from mouth to oesophagus
i.e. food and air must cross over
If coordination lost during swallowing, food may enter trachea –> violent coughing to eject foreign material
Or, air may enter stomach –> eructation (belching)
Rats: Hard palate
Anterior roof of mouth
Body partition separating mouth from nasal cavities
During chewing, food is sorted according to size by rolling it between tongue and hard palate
Rats: Soft palate
Posterior roof of mouth
Lacks core of bone
Rats: Molar teeth
Three molar teeth form a grinding battery on each side of both jaws
Rats: Glottis
Opening into trachea
Rings of cartilage supporting trachea make it easy to identify
Rats: Epiglottis
Ventral to glottis
Triangular flap which closes during swallowing to prevent food or water entering trachea
Rats: Oesophagus
Empty oesophagus is a flattened and transparent tube
Rats: Salivary glands
Shed their secretions into mouth
Colour similar to surrounding CT and muscle
Sheep heart: Venae cavae
Two anterior venae cavae (large right and small left)
One middle posterior venae cava
Which part of the heart forms the apex
Larger left ventricle
Sheep heart: Septum
Separates right and left ventricles
Marks the course of one of the coronary arteries and a cardiac vein
Sheep heart: Atria
Resemble small, collapsed and wrinkled bags
Have little fat –> dark red colour
Sheep heart: Atria - ventral view
Only flabby ear-like auricles visible, as they project from the base of the heart
Sheep heart: Great arteries
Most shrouded with fat
Only one easily seen without dissection - the pulmonary trunk
Sheep heart: Pulmonary trunk
Most ventral of all vessels
Thick, rubbery, cream-coloured wall
Sheep heart: Distinguishing between ventral and dorsal view
- Pulmonary trunk seen in ventral view
- Slanted interventricular sulcus in ventral view, Straighter interventricular sulcus in dorsal view
- Ventral surface is more curved, dorsal surface is flatter
- Auricles always point ventrally