Section 4 Flashcards

1
Q

Conservative treatment for low-back pain consists of therapy for first 4 to 6 weeks which includes physiotherapy, analgesics (NSAIDS), and sometimes epidural steroid injections (only in acute radiculopathy cases). Which of the following are the indications for MRI of lumbosacral spine in patients with backache with subsequent surgical treatment of identified problem appropriately?
● A. Progressive neurologic deficit (e.g., weakness)
● B. Cauda equina syndrome (includes bladder issues, saddle anesthesia)
● C. Intractable pain
● D. Failure of medical treatment
● E. All of the above

A

E. All of the above

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2
Q

Generalized displacement of disk material is defined as displacement of more than 50% or 180 degrees beyond the peripheral limit of disk space. On the other hand, herniation is localized displacement of disk material less than 50% or 180 degrees beyond the limits of the intervertebral disk space. Following statements are true regarding herniation of disk except?
● A. Focal herniation is less than 25% of disk space
● B. Broad based disk herniation is 20 to 25% of the disk herniation
● C. Schmorl’s node is not a type of disk herniation
● D. Protrusion is a type of disk herniation in which the fragment does not have a neck
● E. Extrusion is a type of disk herniation in which the fragment has a neck which is further subdivided into sequestration and migration

A

C. Schmorl’s node is not a type of disk herniation

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3
Q

Dysfunction of nerve root, which may include pain in the distribution of the nerve root or dermatomal sensory disturbances or weakness of the muscle innervated by that nerve root or hypoactive muscle reflexes of the same muscles or a combination of these, is termed as?
● A. Myelopathy
● B. Mechanical low-back pain
● C. Sciatica
● D. Radiculopathy
● E. None of the above

A

D. Radiculopathy

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4
Q

Diminished sensations over medial malleolus plus medial foot, dorsum of foot, and lateral malleolus plus lateral foot suggests L4, L5, and S1 nerve root involvement, respectively. A patient presenting with history of fever with vertebral tenderness and very limited range of spinal motion has most likely
which of the following?
● A. Spinal tumor
● B. Spinal osteoarthritis
● C. Spinal infection
● D. Spinal degenerative disease
● E. Spinal instability

A

C. Spinal infection

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5
Q

Abnormal disk morphology on MRI is loss of T2WI signal intensity (black disk), disk space collapse, Modic changes, and high intensity zones (these findings also frequently occur in asymptomatic patients). Diskography (injection of water-soluble contrast agent directly into the nucleus pulposus of the intervertebral disk) is done through the Kambin’s triangle to find out pathologic disk. Following are included in the boundaries of Kambin’s triangle except?
● A. Exiting nerve root
● B. Superior end plate of inferior vertebral body
● C. Thecal sac
● D. Inferior facet of superior vertebral body
● E. All are included in the boundaries of Kambin’s triangle

A

D. Inferior facet of superior vertebral body

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6
Q

To see dynamic instability in spine, which of the following tests is done?
● A. Flexion–extension lumbar spine X-rays
● B. Oblique X-rays
● C. Standing scoliosis X-rays
● D. Lateral spine X-rays
● E. Anteroposterior spine X-rays

A

A. Flexion–extension lumbar spine X-rays

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7
Q

Following are the advantages of CT scan over MRI except?
● A. Excellent bony detail
● B. Less expensive
● C. Outpatient evaluation
● D. More claustrophobic
● E. Faster scanning

A

D. More claustrophobic

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8
Q

Following are included in the conservative treatment of low-back pain except?
● A. Bed rest for the first 2 to 3 days, activity modification (like prolonged sitting, bending or twisting, limiting lifting objects)
● B. Exercise starting from walking in the first 2 weeks then conditioning exercises for the trunk muscles
● C. NSAIDs and paracetamol
● D. Epidural injection for short-term relief of radicular pain
● E. Oral steroids

A

E. Oral steroids

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9
Q

Which of the following is an indication of lumbar fusion in case of disk herniation?
● A. Evidence of preoperative lumbar spinal deformity or instability
● B. In patients with chronic axial low-back pain associated with radiculopathy
● C. Both A and B
● D. Spondylolisthesis grade 1 without degenerative changes
● E. None of the above

A

C. Both A and B

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10
Q

Which of the following statements is correct regarding surgical option for low-back problems?
● A. Routine HLD or initial recurrence of HLD is treated with standard diskectomy or with microdiskectomy
● B. Foraminal or far-lateral HLD can be treated with partial or total facetectomy, extra canal approach or endoscopic techniques
● C. Only lumbar spinal stenosis can be treated with simple decompression laminectomy
● D. Patients with degenerative spondylolisthesis, stenosis and radiculopathy, adult degenerative scoliosis, or instability are treated with laminectomy plus fusion
● E. All of the above

A

E. All of the above

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11
Q

Failure to satisfactorily improve low-back pain or radiculopathy following back surgery is called as failed back surgery syndrome. Which of the following are the causes of “failed back
surgery syndrome”?
● A. Incorrect initial diagnosis or continued compression caused by residual disk, epidural hematoma, or pseudomeningocele
● B. Permanent nerve root injury preoperatively or after surgery
● C. Adhesive arachnoiditis or diskitis
● D. Spondylosis
● E. All of the above

A

E. All of the above

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12
Q

Surgery for failed back syndrome is recommended only for recurrent or residual disk, instability, or a pseudomeningocele. Following are true regarding MRI study of patients after operation for back pain except?
● A. MRI study done after surgery is always done with contrast if there is no contraindication
● B. Scar enhances on post-contrast MRI study
● C. Disk does not enhance on contrast MRI
● D. MRI is done only without contrast in all cases

A

D. MRI is done only without contrast in all cases

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13
Q

Myelographic classification of arachnoiditis includes which of the following?
● A. Unilateral focal filling defect centered on nerve root sleeve adjacent to disk space
● B. Circumferential constriction around thecal sac
● C. Complete obstruction with stalactites or candle guttering
● D. Infundibular cul de sac with loss of radicular striations
● E. All of the above

A

E. All of the above

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14
Q

In disk herniation, sequestration is when the fragment has lost continuity with the disk of origin. It is a subtype of which of the following?
● A. Disk bulge
● B. Extrusion
● C. Focal
● D. Broad based
● E. Extrusion

A

B. Extrusion

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15
Q

Bone marrow edema associated with acute or subacute inflammation showing hypointensity on T1WI and hyperintensity on T2WI is what Modic type?
● A. I
● B. II
● C. III
● D. IV
● E. V

A

A. I

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16
Q

What is the score of bed-bound patients according to Oswestry disability index?
● A. 0 to 20
● B. 21 to 30
● C. 41 to 60
● D. 61 to 80
● E. 81 to 100

A

E. 81 to 100

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17
Q

Diminished Achilles reflex suggests dysfunction of root of which of the following?
● A. L2
● B. L3
● C. L4
● D. L5
● E. S1

A

E. S1

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18
Q

For diskography, injection of water-soluble contrast agent directly into the nucleus pulposus of the intervertebral disk being studied is performed by percutaneous needle access through which of the following?
● A. Pedicle
● B. Facet
● C. Kambin’s triangle
● D. Anterolateral quadrant
● E. Transforaminal

A

C. Kambin’s triangle

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19
Q

For nonspecific lower backache, for how long bed rest should be allowed?
● A. Not recommended
● B. Few hours
● C. 1 day
● D. 2 days
● E. 4 days

A

E. 4 days

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20
Q

Patients with disabling low-back pain due to two-level degenerative disease without stenosis or spondylolisthesis for ≥ 2 years with radiological evidence of disk degeneration at L4–L5, L5–S1, or both and failed best medical management, should be treated with which of the following?
● A. Thoracolumbar spinal orthosis
● B. Physical therapy
● C. Steroid
● D. Facet capsule injections
● E. Lumbar fusion

A

E. Lumbar fusion

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21
Q

First-time recurrence after diskectomy should be treated with which of the following?
● A. Same as first-time presenting herniated disk
● B. Steroids
● C. Epidural injections
● D. Physical therapy
● E. Anterior lumbar interbody fusion

A

A. Same as first-time presenting herniated disk

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22
Q

Arachnoiditis is an inflammatory condition of the lumbar nerve roots and may present as three different patterns on MRI. What is the pattern where roots adhere to meninges around periphery?
● A. Empty thecal sac
● B. Candle dripping
● C. Guttering
● D. Two central cords
● E. Central adhesion

A

A. Empty thecal sac

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23
Q

What is the myelographic classification of arachnoiditis type for unilateral focal filling defect centered on the nerve root sleeve adjacent to disk space?
● A. I
● B. II
● C. III
● D. IV
● E. V

A

A. I

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24
Q

The nerve root en passant is the nerve in lateral recess that passes through the neural foramen of the level below; for example, for L4–L5 level, it would be L5 nerve root while exiting nerve root at this level would be L4 nerve root. Most of the herniated lumbar disks are paramedian which cause compression on which of the following?
● A. Exiting nerve root
● B. Traversing nerve root
● C. Both A and B
● D. It causes thecal sac compression only
● E. None of the above

A

B. Traversing nerve root

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25
Q

Which of the following statements is incorrect regarding clinical findings with herniated lumbar disk?
● A. Symptoms may start off with back pain, which after days or weeks gradually or sometimes suddenly yields to radicular pain often with reduction of the back pain
● B. Pain is relieved upon flexing the knee and thigh (e.g., with a pillow under the knees)
● C. Remaining in any position (sitting, standing, or lying) for too long may also exacerbate the pain, sometimes necessitating position changes at intervals that range from every few minutes to 10 to 20 minutes
● D. Pain is increased with coughing, sneezing, or straining at the stool
● E. Bladder symptoms are never present with a herniated lumbar disk

A

E. Bladder symptoms are never present with a herniated lumbar disk

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26
Q

Which of the following signs are used to test tension on nerve roots in case of radiculopathy?
● A. Lasegue’s sign also known as straight leg raise sign (with the patient supine, the afflicted limb is raised by the ankle until pain is solicited, which should occur at angle less than 60 degrees and consists of leg pain or paresthesias in the distribution of pain)
● B. Cram test (with the patient supine, the symptomatic leg is raised with the knee slightly flexed and then extending the knee will produce pain similar to Lasegue’s sign)
● C. Crossed straight leg raising test also known as Fajersztajn’s sign (SLR on the painless leg cause contralateral limb pain)
● D. Femoral stretch test also known as reverse straight leg raising, which is positive with L2, L3, or L4 nerve root compression
● E. All of the above

A

E. All of the above

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27
Q

The most common level of herniated lumbar disk is L5–S1 which is 45 to 50%, the second most common level is L4–L5 which is 40 to 45%, while L3–L4 is involved in only 3 to 10% of cases. Which of the following are the symptoms caused by the S1 nerve root compression?
● A. Diminished ankle jerk (Achilles)
● B. Motor weakness of gastrocnemius causing weak plantar flexion
● C. Decreased sensations in the area of lateral malleolus and lateral foot
● D. Pain distribution in the posterior lower extremity often up to the ankle
● E. All of the above

A

E. All of the above

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28
Q

Cauda equina syndrome causes urinary retention, saddle anesthesia, significant motor weakness, and low-back pain. Following are the causes of this syndrome except?
● A. Compression of the cauda equina by massive disk herniation or tumor or free fat graft following surgery or trauma or spinal epidural hematoma
● B. Infection which may cause compression by epidural abscess or vascular compromise resulting from local septic thrombophlebitis
● C. Neuropathy caused by inflammation or ischemia
● D. Rheumatoid arthritis
● E. Ankylosing spondylitis

A

D. Rheumatoid arthritis

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29
Q

What is the desirable time of surgery after development of cauda equina syndrome?
● A. Within 48 hours
● B. Within 24 hours
● C. Within 12 hours
● D. Within 6 hours
● E. None of the above

A

B. Within 24 hours

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30
Q

Which of the following is an indication of surgery in a patient with herniated lumbar disk?
● A. Failure of nonsurgical management which is done for almost 5 to 8 weeks
● B. Patients with cauda equina syndrome
● C. Patients with progressive motor deficit
● D. Intolerable pain despite the use of adequate narcotic pain medication
● E. All of the above

A

E. All of the above

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31
Q

Surgical options for lumbar radiculopathy include transcanal approaches like standard open lumbar laminectomy and diskectomy, microdiskectomy, or sequestrectomy. Which of the following indications are utilized by proponents for intradiskal procedures like automated percutaneous lumbar diskectomy (nucleoplasty), laser disk decompression, percutaneous endoscopic lumbar diskectomy, and intradiskal endothermal therapy?
● A. Contained disk herniation
● B. Best for L4–L5 herniated disk
● C. Not recommended in severe neurologic deficit
● D. All of the above

A

D. All of the above

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32
Q

Common complications after operation for herniated lumbar disk include superficial wound infection, deep wound infection, increased motor deficit, unintended incidental durotomy, recurrent herniated lumbar disk, and postoperative urinary retention. What are the rates of superficial infection, deep infection, and incidental durotomy, respectively?
● A. 0.9 to 5%, less than 1%, and 0.3 to 13%
● B. 1%, 5%, and 13%
● C. 0.1%, 0.5%, and 0.3%
● D. None of the above

A

A. 0.9 to 5%, less than 1%, and 0.3 to 13%

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33
Q

What is the possible sequalae of dural opening?
● A. CSF leak (contained or pseudomeningocele or external, CSF fistula)
● B. Herniations of nerve roots through the opening
● C. Associated nerve root contusion, laceration, or injury to the cauda equina
● D. CSF leak may collapse thecal sac and cause bleeding from epidural blood vessels
● E. All of the above

A

E. All of the above

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34
Q

Most herniated lumbar disks occur posteriorly and slightly off to one side within which of the following?
● A. Central canal zone
● B. Foraminal zone
● C. Extraforaminal zone
● D. Far lateral zone
● E. Intravertebrally

A

A. Central canal zone

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35
Q

A herniated disk at the level of L4–L5 mostly involves root of which of the following?
● A. L3
● B. L4
● C. L5
● D. S1
● E. Filum terminale

A

C. L5

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36
Q

A foraminal herniated disk at the level of L4–L5 mostly involves root of which of the following?
● A. L3
● B. L4
● C. L5
● D. S1
● E. Filum terminale

A

B. L4

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37
Q

Which of the following is the most specific nerve root tension sign?
● A. Lasegue’s test
● B. Cross SLR
● C. Reverse SLR
● D. Hoover test
● E. FABER/Patrick test

A

B. Cross SLR

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38
Q

Which of the following is a hip motion test for sacroiliitis?
● A. Lasegue’s test
● B. Cross SLR
● C. Reverse SLR
● D. Hoover test
● E. FABER/Patrick test

A

E. FABER/Patrick test

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39
Q

What is the test used to distinguish unilateral functional weakness of iliopsoas from organic weakness using synergistic contraction of the contralateral gluteus medius?
● A. Lasegue’s test
● B. Cross SLR
● C. Reverse SLR
● D. Hoover test
● E. FABER/Patrick test

A

D. Hoover test

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40
Q

Knee jerk is diminished (Westphal’s sign) in herniated lumbar disk of which level?
● A. L2–L3
● B. L3–L4
● C. L4–L5
● D. L5–S1
● E. S1–S2

A

B. L3–L4

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41
Q

What is the most consistent finding in cauda equine syndrome?
● A. Urinary retention
● B. Saddle anesthesia
● C. Motor weakness in one limb
● D. Paraplegia
● E. Sciatica

A

A. Urinary retention

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42
Q

Which of the following is not an intradiskal procedure for lumbar radiculopathy?
● A. Chemonucleolysis
● B. Automated percutaneous lumbar diskectomy
● C. Percutaneous endoscopic intradiskal diskectomy
● D. Sequesterectomy
● E. Laser disk decompression

A

D. Sequesterectomy

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43
Q

A diabetic patient with lumbar radiculopathy was operated on and postoperatively he was blind. What is the most common cause?
● A. Anterior ischemic optic neuropathy
● B. Posterior ischemic optic neuropathy
● C. Retinal artery occlusion
● D. Cortical blindness
● E. Diabetic retinopathy

A

A. Anterior ischemic optic neuropathy

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44
Q

Extreme lateral herniated lumbar disk occurs most commonly at which level?
● A. L1–L2
● B. L2–L3
● C. L3–L4
● D. L4–L5
● E. L5–S1

A

D. L4–L5

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45
Q

Which of the following is a less well-documented sequelae of dural opening?
● A. CSF fistula
● B. Herniation of nerve roots through opening
● C. Associated nerve root contusion, laceration, or injury to the cauda equina
● D. CSF leak collapses the thecal sac and may increase blood loss from epidural bleeding
● E. Arachnoiditis

A

E. Arachnoiditis

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46
Q

Thoracic disk herniation constitutes only 0.25% of herniated disks and usually occurs at or below T8. These disks are frequently calcified. Pain and sensory disturbance are in a band-like distribution radiating anteriorly and inferiorly along the involved root’s dermatome. What is the indication of surgery
in these cases?
● A. Refractory pain
● B. Progressive myelopathy
● C. Both A and B
● D. Radiculopathy
● E. None of the above

A

C. Both A and B

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47
Q

CT should be obtained in cases of thoracic herniated disk along with noncontrast MRI of thoracic spine as most of the disks in this region are calcified. Which of the following are the options for open surgical approaches for these disks?
● A. Posterior midline laminectomy
● B. Posterolateral like lateral gutter (laminectomy plus removal of pedicle), transpedicular, costotransversectomy, and transfacet pedicle sparing
● C. Anterolateral (transthoracic) usually through the pleural space
● D. Lateral extracavitary (retrocoelomic) which is posterior to the pleural space
● E. All of the above

A

E. All of the above

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48
Q

Which of the following is a correct match of appropriate surgical approach for the given pathology?
● A. Laminectomy for posteriorly located tumor
● B. Posterolateral (transpedicular) for radicular pain with lateral disk herniation or for biopsy of tumor
● C. Lateral (costotransversectomy) for midline disk, good ipsilateral access but poor access to opposite side
● D. Transthoracic for midline lesions especially for reaching both sides of the cord
● E. All of the above

A

E. All of the above

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49
Q

To access T4–T5 disk space, which rib needs to be removed?
● A. T4
● B. T5
● C. Both A and B
● D. T5 and T6
● E. T4 and T3

A

B. T5

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50
Q

Indications of transthoracic approach for thoracic disk disease include central fragment or calcified disk, and burst fracture of thoracic spine. Following are the advantages of transthoracic approach except?
● A. It provides excellent anterior approach
● B. It causes little compromise of stability
● C. It deals easily with pathology lying posterior to the cord
● D. There is low risk of mechanical cord injury with this approach
● E. All of the above

A

C. It deals easily with pathology lying posterior to the cord

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51
Q

Which of the following statements regarding neuromonitoring during thoracic spine disease surgery is correct?
● A. It consists of MEP and SSEP
● B. It is not required for surgery at this level
● C. Injury to cord at this level cannot be prevented
● D. None of the above

A

A. It consists of MEP and SSEP

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52
Q

There is risk of injury to radicular artery which may compromise the spinal cord blood supply. How much posterior rib along with transverse process needs to be removed?
● A. 3 to 4 cm
● B. 4 to 5 cm
● C. 5 to 3 cm
● D. More than 5 cm
● E. Less than 6 cm

A

B. 4 to 5 cm

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53
Q

What skin incision can be used for costotransversectomy procedure?
● A. Curved paramedian skin incision
● B. Midline incision
● C. Both A and B
● D. T-shaped incision
● E. None of the above

A

C. Both A and B

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54
Q

What is the most common symptom after thoracic disk herniation?
● A. Pain
● B. Sensory changes
● C. Motor changes
● D. All occur at some time

A

D. All occur at some time

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55
Q

What is the percentage of occurrence pain in case of thoracic disk disease?
● A. 60%
● B. 23%
● C. 18%
● D. 8

A

A. 60%

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56
Q

About 75% of thoracic disk herniations are below which level?
● A. T6
● B. T7
● C. T8
● D. T10
● E. T12

A

C. T8

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57
Q

For thoracic spine surgery, which of the following is not a posterolateral approach?
● A. Transthoracic
● B. Lateral gutter
● C. Transpedicular
● D. Costotransversectomy
● E. Transfacet pedicle sparing

A

A. Transthoracic

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58
Q

For a central disk herniation, especially when calcified, which approach has the lowest incidence of cord injury with the best operative results?
● A. Transfacet pedicle sparing
● B. Transthoracic
● C. Lateral extracavitary approach
● D. Costotransversectomy
● E. Transpedicular approach

A

B. Transthoracic

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59
Q

Which of the following is the best approach for radicular pain with lateral disk herniation and biopsy of tumor?
● A. Transfacet pedicle sparing
● B. Transthoracic
● C. Lateral extracavitary approach
● D. Costotransversectomy
● E. Transpedicular approach

A

E. Transpedicular approach

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60
Q

During costotransversectomy, to access the vertebral body of T6, which rib needs to be removed?
● A. 5th
● B. 7th
● C. 5th and 6th
● D. 6th and 7th
● E. 5th, 6th, and 7th

A

D. 6th and 7th

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61
Q

What is the best approach for midline thoracic spine lesions, especially for reaching both sides of the cord?
● A. Laminectomy
● B. Posterolateral transpedicular
● C. Transpedicular facet sparing
● D. Costotransversectomy
● E. Transthoracic

A

E. Transthoracic

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62
Q

Which of the following statements are correct regarding cervical disk syndromes?
● A. C4–C5 herniated cervical disk is only 2%; it causes C5 nerve root compression, diminished deltoid and pectoralis reflexes, motor weakness in deltoid, and paresthesia or hypoesthesia in shoulder
● B. C5–C6 cervical disk herniation is 19%; it causes C6 nerve root compression, diminished biceps and brachioradialis reflex, forearm flexion weakness and paresthesia, and hypesthesia in upper arm, thumb, and radial forearm
● C. C6–C7 cervical disk herniation is 69%; it causes 7 nerve root compression, diminished triceps reflex, motor weakness of forearm extension (wrist drop), and paresthesia hypesthesia in fingers 2 and 3 with all finger tips
● D. C7–T1 cervical disk herniation is 10%; it causes C8 nerve root compression, diminished finger jerk, motor weakness in hand intrinsics, and paresthesia hypesthesia in fingers 4 and 5
● E. All of the above

A

E. All of the above

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63
Q

Evaluation for radiculopathy includes LMN findings which are weakness in one myotome group with atrophy and fasciculations present, sensory loss in dermatome similar to that of myotomal weakness, and eliciting muscle stretch reflexes and positive mechanical signs with reproduction of radicular
symptoms with mechanical loading of the head. Evidence of cervical cord involvement (myelopathy) is UMN findings in the lower extremity and presence of pathologic reflexes like Hoffmann’s reflex, Babinski sign, and ankle clonus. Following signs
are useful in evaluating cervical radiculopathy except?
● A. Painful limitation of neck movement in almost all herniated cervical disk patients. Neck extension usually aggravates pain when cervical disk disease is present. Some patients find relief in evaluating the arm and cupping the back or the top of the head with the hand (abduction relief sign)
● B. Lhermitte’s sign (electric shock like sensation radiating down the spine)
● C. Spurling’s sign
● D. Axial manual traction of a supine patient with 10 to 15 kg resulting in reduction or disappearance of radicular symptoms is a positive finding
● E. Positive shoulder abduction test in which lifting of hand above head causes reduction or disappearance of radicular signs
● F. Positive Hoffmann’s sign

A

F. Positive Hoffmann’s sign

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64
Q

Over 90% of patients with acute cervical radiculopathy due to cervical disk herniation can improve without surgery and regression of an extruded cervical disk has been demonstrated
radiographically. Conservative management of cervical disk includes the following except?
● A. Physical therapy which may include intermittent cervical traction (gradually escalating up to 10–15 pounds for 10–15 minutes for two to three times daily)
● B. Use of NSAIDs
● C. Use of short-course tapering steroids
● D. Trigger points injections and facet blocks have no role
● E. Epidural steroid injection (not used as often as in lumbar spine)

A

D. Trigger points injections and facet blocks have no role

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65
Q

Routine anterior approach for cervical spine surgery is usually able to access levels C3 and C7. While in patients with short thick neck, access may be even more limited. Which of the following are advantages of anterior approach over posterior approach?
● A. Safe removal of anterior osteophytes
● B. Fusion of disk space affords immobility, while there is 10% risk of immobility with extensive approach
● C. The only viable means of directly dealing with centrally herniated disk
● D. All of the above

A

D. All of the above

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66
Q

For ACDF, a horizontal skin incision in mediolateral direction is made. C5–C6 disk is at the level of which of the following?
● A. Hyoid bone
● B. Thyroid cartilage
● C. Cricoid cartilage
● D. Cricothyroid membrane
● E. None of the above

A

C. Cricoid cartilage

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67
Q

Choices of graft for anterior cervical fusion includes autologous graft (from iliac crest), nonautologous bone (cadaveric), bone substitutes (hydroxylapatite), or synthetic (PEEK, titanium) filled with osteogenic material. All of the following are benefits of anterior cervical plating except?
● A. It reduces pseudoarthrosis rate and graft problem
● B. It helps to maintain lordosis
● C. It is recommended for improvement of clinical outcome
● D. It is recommended to improve arm pain

A

C. It is recommended for improvement of clinical outcome

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68
Q

Postoperative check following ACDF includes which of the following?
● A. Checking for evidence of airway obstruction (check for hematoma, respiratory distress, extreme difficulty in swallowing, tracheal deviation)
● B. Weakness of nerve root of the level operated
● C. Long tract signs (Babinski) which may indicate cord compression by spinal epidural hematoma
● D. Hoarseness of voice which may show RLN injury
● E. All of the above

A

E. All of the above

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69
Q

ACDF complications include the following except?
● A. Exposure injuries (perforation of viscus like pharynx or esophagus or trachea, vocal cord paresis with incidence of 4% permanent and 11% temporary, vertebral artery injury with 0.3% incidence, carotid injury, CSF fistula, Horner syndrome, thoracic duct injury, thrombosis of internal jugular vein)
● B. Spinal cord or nerve root injury
● C. Bone fusion problems like failure of fusion (pseudoarthrosis), anterior kyphotic angulation, graft extrusion
● D. Wound infection, postoperative pneumothorax or hemothorax
● E. All of the above

A

E. All of the above

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70
Q

Indications for posterior keyhole laminotomy include which of the following?
● A. Monoradiculopathy with posterolateral soft disk sequestration
● B. Radiculopathy in patients who are professional singers or speakers
● C. For lower or upper cervical nerve root compression where anterior approach is more difficult
● D. In patients with herniated disk where it is desired to avoid fusion
● E. All of the above

A

E. All of the above

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71
Q

Posterior cervical decompression is usually reserved for which of the following cases?
● A. Multiple cervical disks or osteophytes (ACD is usually used to treat only two or three levels without myelopathy)
● B. Where cervical stenosis is more diffuse and more significant as compared to anterior pathology
● C. In professional speakers or singers
● D. All of the above

A

D. All of the above

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72
Q

A patient presented with weakness of forearm flexion, paresthesias in upper arm and thumb, and diminished biceps reflex. What is the level of herniated cervical disk?
● A. C2–C3
● B. C3–C4
● C. C4–C5
● D. C5–C6
● E. C6–C7

A

D. C5–C6

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73
Q

Which physical examination test for cervical disk herniation is analogous to straight leg raising test for lumbar disk herniation?
● A. Spurling test
● B. Axial manual spinal traction
● C. Shoulder abduction test
● D. FABER test
● E. Patrick test

A

A. Spurling test

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74
Q

What is the accuracy of CT myelogram for cervical disk disease?
● A. 70%
● B. 75%
● C. 80%
● D. 90%
● E. 98%

A

E. 98%

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75
Q

Which of the following is the most frequent radiculopathy mimicking carpal tunnel syndrome?
● A. C2
● B. C4
● C. C5
● D. C6
● E. C7

A

D. C6

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76
Q

How many patients with acute cervical radiculopathy due to cervical disk herniation can improve without surgery?
● A. 70%
● B. 80%
● C. 85%
● D. 90%
● E. 98

A

D. 90%

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77
Q

A patient underwent ACDF and developed Horner syndrome. Sympathetic plexus lies within which of the following?
● A. Cricothyroid
● B. Longus coli
● C. Sternocleidomastoid
● D. Omohyoid
● E. Belly of digastric

A

B. Longus coli

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78
Q

The addition of an anterior plate to an ACDF is recommended for what purpose?
● A. Reduce the pseudarthrosis rate
● B. Reduce graft problems
● C. To maintain lordosis
● D. Improve clinical outcome
● E. To improve arm pain

A

D. Improve clinical outcome

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79
Q

A patient developed difficulty in swallowing after ACDF. Laryngoscopy for postoperative dysphagia in this case is indicated if symptoms persist for how long?
● A. 24 hours
● B. 3 days
● C. 5 days
● D. > 2 weeks
● E. > 1 month

A

D. > 2 weeks

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80
Q

What is the most common muscle flap for repair of esophageal perforation?
● A. Sternocleidomastoid
● B. Radial forearm
● C. Pectoralis
● D. Infrahyoid
● E. Omohyoid

A

A. Sternocleidomastoid

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81
Q

Cervical spinal spondylosis usually implies a more widespread age-related degenerative condition of the cervical spine including various combinations of which of the following?
● A. Congenital cervical spinal stenosis (the shallow cervical canal) and degeneration of the intervertebral disk producing a focal stenosis due to a cervical bar which can be due to an osteophytic spur or protrusion of intervertebral disk material
● B. Hypertrophy of lamina, dura, articular facets, and ligaments (ligamentum flavum, PLL, OPLL, ossification of ligamentum flavum) plus subluxation due to disk and facet joint degeneration
● C. Altered mobility and telescoping of the spine due to loss of height of VBs and disks, which is also called as shingling of laminae
● D. Alteration of normal lordosis curvature including excessive lordosis or kyphosis
● E. All of the above

A

E. All of the above

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82
Q

In case of myelopathy, the histological findings are degeneration of the central gray matter at the level of compression, degeneration of the posterior column above the lesion, and demyelination of the lateral columns especially corticospinal tracts (anterior spinal tracts are relatively spared). Following are included in the pathogenesis of cervical myelopathy except?
● A. Direct cord compression between osteophytic bars and hypertrophy or infolding of the ligamentum flavum especially if superimposed on congenital narrowing or cervical subluxations
● B. Ischemia due to compression of the vascular structures
● C. Repeated local cord trauma by normal movements in the presence of protruded disks and/or osteophytic bars
● D. Compression due to hypertrophy of the anterior longitudinal ligament

A

D. Compression due to hypertrophy of the anterior longitudinal ligament

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83
Q

Cervical spondylosis is the most common cause of myelopathy in patients more than 55 years of age, and cervical spondylotic myelopathy (CSM) is rare in patients less than 40 years of age. CSM develops in almost all patients with more than or equal to 30% narrowing of cross-sectional area of the cervical
spinal canal. Clinical problems that can occur with cervical spondylosis include myeloradiculopathy which includes radiculopathy and myelopathy and the second one is pain and paresthesias in the head, neck, and shoulders with little or no suggestion of radiculopathy nor abnormal physical findings. Which of the following statements regarding individual symptoms of CSM is correct?
● A. The earliest motor findings are typically weakness in the triceps and hand intrinsics with wasting of the hand muscles and slow stiff opening and closing of the fist. Clumsiness with fine motor skills (writing, buttoning buttons) is common. There is often proximal weakness of lower extremities
(mild to moderate iliopsoas weakness in 54%) and spasticity of the lower extremities
● B. Sensory disturbance may be minimal and when it occurs it is like glove distribution sensory loss in the hands. A sensory level may occur a number of levels below the area of cord compression. Lower extremity often exhibits loss of vibratory sense (in 82% cases) and occasionally has reduced pin prick
sensations (9%)
● C. In 72 to 87% of cases, reflexes are hyperactive at a varying distance below the level of stenosis and clonus, Babinski, or Hoffmann’s sign may be present. Dynamic Hoffmann’s sign may be more sensitive while inverted radial reflex is said to be pathognomonic of CSM
● D. Urinary urgency and frequency are common in CSM, while urinary incontinence is rare. Anal sphincter disturbances are uncommon
● E. All of the above

A

E. All of the above

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84
Q

Which of the following are included in the cervical spondylotic myelopathic syndromes?
● A. Transverse lesion syndrome: Most frequent syndrome, possibly an end stage of the disease process
● B. Motor system syndrome: Mixture of lower motor neuron findings in the upper extremity and upper motor neuron finding in the lower extremities which can mimic ALS
● C. Central cord syndrome: Motor and sensory involvement producing greater deficit in the upper extremities than the lower extremities results in the so-called numb-clumsy hand syndrome. Lhermitte’s sign may be more common in this group
● D. Brown-Sequard syndrome: Upper motor neuron weakness ipsilateral to the side of greater narrowing while contralateral impairment of pain, temperature, and joint position sense
● E. Brachialgia and cord syndrome: Primarily radiculopathy
with lesser association with long tract involvement
● F. All of the above

A

F. All of the above

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85
Q

According to the modified Japanese Orthopedic Association Scale, severe spondylotic myelopathy implies Benzel mJOA grade of how much?
● A. More than or equal to 15
● B. 12 to 14
● C. Less than or equal to 11
● D. More than 9
● E. None of the above

A

C. Less than or equal to 11

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86
Q

Amyotrophic lateral sclerosis (ALS) is anterior horn motor neuron disease which can mimic motor system syndrome of cervical spondylotic myelopathy (CSM). Triad of ALS are atrophic weakness of hands and forearms, mild lower extremity spasticity, and diffuse hyperreflexia. Which of the following features can help differentiate ALS from CSM?
● A. In ALS sensory symptoms are conspicuously absent while in CSM hand numbness may occur
● B. Bulbar symptoms like dysarthria and hyperactive jaw jerk may occur in ALS but are absent in CSM
● C. ALS causes extensive weakness/muscle atrophy of hands usually with fasciculations
● D. ALS will cause LMN findings in the tongue like visible fasciculations and positive sharp waves on EMG or in the lower extremity like atrophy and fasciculations
● E. CSM or herniated cervical disk usually includes neck and shoulder pain, limitation of neck movements, sensory changes, and LMN findings restricted to one or two spinal cord segments
● F. All of the above

A

F. All of the above

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87
Q

Cervical canal stenosis is spina canal narrowing sufficient to produce spinal cord compression and thereby spinal cord symptoms. Cervical spondylotic myelopathy (CSM) is rare in patients with canal diameter more than 16 mm, and its risk is increased in patients with less than 14-mm diameter. Values
less than or equal to 10 mm are likely to be associated with myelopathy while in average patients with CSM, canal diameter is around 11.8 mm. Which of the following findings are found in CSM patients with poor outcome?
● A. Multilevel hyperintensity within the spinal cord parenchyma in T2WI
● B. Single-level T2WI hyperintensity with corresponding T1WI hypointensity
● C. Spinal cord atrophy (transverse area less than 45 mm2)
● D. Banana-shaped cord in axial images
● E. Snake eyes within the spinal cord on axial T2WI may be related to cystic necrosis of cord and is correlated with pooroutcome
● F. All of the above

A

F. All of the above

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88
Q

Nonoperative management of cervical spondylotic myelopathy includes which of the following?
● A. Prolonged immobilization with rigid cervical bracing
● B. Modified activities to eliminate high-risk activities
● C. Bed rest
● D. Anti-inflammatory medications
● E. All of the above

A

E. All of the above

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89
Q

Patients with mJOA score of more than 12 may derive significant improvement from surgery and deterioration from this point may be ominous. For degenerative cervical radiculopathy, patients do better with anterior decompression with/without fusion and cause rapid relief of pain in arm and neck
and of sensory loss within 3 to 4 months while relief of symptoms like weakness of wrist extension, elbow extension, shoulder abduction, and internal rotation may take up to how long?
● A. 9 months
● B. 6 months
● C. 3 months
● D. More than or equal to 12 months
● E. More than 18 months

A

D. More than or equal to 12 months

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90
Q

Situations where posterior approach would generally be the initial choice include which of the following?
● A. Congenital cervical stenosis
● B. Disease over more than or equal to three levels
● C. Cases of OPLL
● D. Primary posterior pathology like infolding of ligamentum flavum
● E. All of the above

A

E. All of the above

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91
Q

Hard calcified disks are commonly found in thoracic spine. Which of the following is sometimes called a hard disk in cervical spine?
● A. Shallow canal
● B. Osteophyte
● C. Lamina
● D. Hypertrophied ligamentum flavum
● E. Facet joint capsule

A

B. Osteophyte

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92
Q

The bow stringing of cervical spinal cord refers to which of the following?
● A. Kyphosis
● B. Lordosis
● C. Ossified posterior longitudinal ligament
● D. Hypertrophied ligamentum flavum
● E. Multilevel disk protrusion

A

A. Kyphosis

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93
Q

What is the earliest motor finding in cervical spondylotic myelopathy (CSM)?
● A. Weakness of triceps and hand intrinsics
● B. Proximal weakness of lower extremities
● C. Spasticity of lower limb
● D. Weakness of biceps
● E. Weak extension of elbow

A

A. Weakness of triceps and hand intrinsics

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94
Q

During degenerative cervical spine disease, which of the following is usually spared?
● A. Gray matter
● B. Posterior columns
● C. Lateral columns
● D. Corticospinal tracts
● E. Anterior spinal tracts

A

E. Anterior spinal tracts

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95
Q

What is the pathognomonic test for cervical spondylosis myelopathy?
● A. Lhermitte’s sign
● B. Hoffmann’s sign
● C. Dynamic Hoffmann sign
● D. Inverted radial reflex
● E. Babinski’s reflex

A

D. Inverted radial reflex

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96
Q

Amyotrophic lateral sclerosis may be difficult to differentiate from cervical spondylosis myelopathy and patients with the former are wrongly operated on for the suspicion of the latter. What is a typical feature of ALS that can differentiate it from cervical spondylotic myelopathy (CSM)?
● A. Absence of sensory findings
● B. Absence of bulbar symptoms
● C. Absence of tongue fasciculations
● D. Absence of widespread motor weakness with fasciculations
● E. MR

A

A. Absence of sensory findings

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97
Q

What is the ratio of the AP diameter of the spinal canal at the mid vertebral body level to the vertebral body at the same location?
● A. Pavlov’s
● B. Lhermitte’s
● C. Steele’s
● D. Babinski’s
● E. Spence’s

A

A. Pavlov’s

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98
Q

What is the cervical spine canal diameter above which a patient rarely develops myelopathy?
● A. 4 mm
● B. 8 mm
● C. 10 mm
● D. 12 mm
● E. 16 mm

A

E. 16 mm

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99
Q

The transverse area of the spinal cord is reduced at the level of maximum compression in cervical spondylosis myelopathy and on axial images what does the cord look like?
● A. Double lumen
● B. Tram track
● C. Owl’s eye
● D. Bamboo
● E. Banana

A

E. Banana

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100
Q

For cervical spondylotic myelopathy (CSM), a posterior approach is favored if the disease spans over how many levels?
● A. > 1 level
● B. > 2 levels
● C. > 3 levels
● D. > 4 levels
● E. > 5 levels

A

C. > 3 levels

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101
Q

For posterior approach decompression of cervical spine, a standard laminectomy refers to laminectomy at what level?
● A. C1
● B. C2
● C. C3–C6
● D. C2–C7
● E. C1–T1

A

C. C3–C6

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102
Q

A motor decline of deltoid muscle strength by ≥ 1 grade within 6 weeks of cervical spine surgery is which postoperative palsy?
● A. C3 palsy
● B. C4 palsy
● C. C5 palsy
● D. C6 palsy
● E. C7 palsy

A

C. C5 palsy

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103
Q

Scoliosis is defined as lateral curvature of the spine in the coronal (frontal) plane with Cobb angle more than what?
● A. 8 degrees
● B. 10 degree
● C. 12 degrees
● D. 14 degrees
● E. 16 degrees

A

B. 10 degree

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104
Q

Cobb angle can be measured between two lines, first drawn tangential to the superior endplate of superior vertebra and the second is drawn tangential to the inferior endplate of inferior vertebra. How can this angle be obtained?
● A. Sagittal X-ray
● B. Coronal X-ray
● C. Sagittal CT scan
● D. Coronal MRI films
● E. None of the above

A

B. Coronal X-ray

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105
Q

The absolute value of lumbar spinal lordosis should be about 30 degrees greater than the absolute value of the thoracic kyphosis (e.g., a patient with thoracic kyphosis of 20 degrees should have a lumbar lordosis of approximately–50 degrees). What should be range of lumbar lordosis in normal individuals?
● A. 10 to 30 degrees
● B. 10 to 40 degrees
● C. 20 to 40 degrees
● D. 20 to 50 degrees
● E. 20 to 60 degrees

A

B. 10 to 40 degrees

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106
Q

Sagittal vertical axis is a horizontal distance from the posterior edge of the S1 endplate to a plumb line dropped from the mid C7 vertebral body. What is its normal value?
● A. < 3 cm
● B. < 7 cm
● C. < 5 cm
● D. < 9 cm
● E. < 1 cm

A

C. < 5 cm

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107
Q

Pelvic tilt is the angle between the vertical reference line and a line drawn from the midpoint of the femoral head to the midpoint of the S1 endplate. What should be the normal value
of this angle?
● A. 5 to 15 degrees
● B. 10 to 20 degrees
● C. 10 to 25 degrees
● D. 15 to 30 degrees
● E. 20 to 30 degrees

A

C. 10 to 25 degrees

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108
Q

Pelvic incidence is the angle between a point perpendicular to the S1 endplate and a line drawn from the midpoint of the femoral head to the midpoint of the S1 endplate. What is its normal value approximately?
● A. 35 degrees
● B. 45 degrees
● C. 50 degrees
● D. 55 degrees
● E. 60 degrees

A

C. 50 degrees

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109
Q

Sacral slope is the angle between the horizontal reference line and the S1 endplate and it normal value is 36 to 42 degrees. Which of the following statements is correct?
● A. SS = PI− PT
● B. SS = PT− PI
● C. SS = PI + PT
● D. SS = PT multiplied by PI
● E. None of the above

A

A. SS = PI− PT

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110
Q

Lumbar lordosis is the angle between the top of S1 and the top of L1 vertebra. What is its normal value?
● A. 10 to 30 degrees
● B. 20 to 40 degrees
● C. 20 to 50 degrees
● D. 10 to 40 degrees

A

B. 20 to 40 degrees

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111
Q

Thoracic kyphosis is the angle between top of T4 and the bottom of the T12 vertebrae. What is its normal value?
● A. 41 ± 12 degrees
● B. 39 ± 12 degrees
● C. 37 ± 12 degrees
● D. 43 ± 12 degrees

A

A. 41 ± 12 degrees

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112
Q

The spine is generally kyphotic between T1 and T12 while between L1 and L5 it is what?
● A. Scoliotic
● B. Lordotic
● C. Kyphotic
● D. Hyperacusis
● E. None of the above

A

B. Lordotic

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113
Q

Scoliosis is defined as lateral curvature of the spine in the coronal plane with what Cobb angle?
● A. > 10 degrees
● B. > 15 degrees
● C. > 20 degrees
● D. > 25 degrees
● E. > 30 degrees

A

A. > 10 degrees

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114
Q

The vertebra whose center is most laterally displaced from the central line is called what?
● A. Center
● B. Apex
● C. Master
● D. Dextro
● E. Levo

A

B. Apex

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115
Q

As compared to thoracic spine, the lumbar spine should have lordosis more than what?
● A. 5 degrees
● B. 10 degrees
● C. 15 degrees
● D. 20 degree
● E. 30 degrees

A

E. 30 degrees

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116
Q

Pelvic tilt is the angle between the vertical reference line (VRL) and a line drawn from the midpoint of the femoral head to the midpoint of the S1 endplate. Normally, it should be less than what?
● A. 20 degrees
● B. 30 degrees
● C. 40 degrees
● D. 90 degrees
● E. 180 degrees

A

A. 20 degrees

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117
Q

Patients with higher sacral slope have a higher chance of developing which of the following?
● A. Spinal stenosis
● B. Spondylolisthesis
● C. Scoliosis
● D. Kyphosis
● E. Lordosis

A

B. Spondylolisthesis

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118
Q

Lumbar lordosis (LL) is the angle between the top of S1 and the top of L1. For pelvic harmony, LL should be within how many degrees of pelvic incidence (PI)?
● A. 9
● B. 11
● C. 13
● D. 15
● E. 20

A

A. 9

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119
Q

According to Roussouly classification of lumbar lordosis if the SS = 35–45 degrees, apex of LL is at the center of L4 VB. What is the implication of this type?
● A. LL is distributed over only approximately 3 lumbar levels
● B. Entire spine is hypolordotic and hypokyphotic
● C. Well-balanced spine
● D. LL is distributed over > 5 levels
● E. PI is usually high

A

C. Well-balanced spine

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120
Q

Scoliosis is defined as lateral curvature of the spine in the coronal plane (frontal plane) with Cobb angle greater than 10 degrees. Which of the following is the type of idiopathic scoliosis which occurs at the age of 10 to 17 years and with overwhelming female predominance?
● A. Congenital scoliosis
● B. Infantile scoliosis
● C. Juvenile scoliosis
● D. Adolescent idiopathic scoliosis
● E. None of the above

A

D. Adolescent idiopathic scoliosis

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121
Q

Patients with idiopathic scoliosis are more commonly females and mostly have dextroscoliosis (convex to right side). Imaging for these patients consist of lateral and neutral PA coronal X-rays and left-bending plus right-bending coronal X-rays are done only if surgery is planned. Which of the following statements is incorrect regarding treatment of these patients?
● A. Treatment is based on skeletal maturity and magnitude of scoliosis
● B. Growing patients with curves less than 25 degrees or skeletally mature patients with curves less than 45 to 50 degrees are managed with observation only
● C. Bracing prevents progression but does not correct scoliosis and bracing makes no sense in skeletally mature patients
● D. Use of bracing in patients with curves 25 to 40 degrees who are still growing or in skeletally immature patients with curves more than 45 degrees is done to tide them over until they can have surgery
● E. For growing patients with early scoliosis, there is no need of fixation or vertebral body tethering

A

E. For growing patients with early scoliosis, there is no need of fixation or vertebral body tethering

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122
Q

“Reduced growth in areas of compressed cartilage (physes) in the curve concavity may result in progression of scoliosis through development of vertebral body wedging from asymmetric growth”; this principle for adult idiopathic scoliosis is known as what?
● A. Heuber principle
● B. Hueter-Volkmann principle
● C. Heishemer-Volkmann principle
● D. Spence principle
● E. None of the above

A

B. Hueter-Volkmann principle

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123
Q

Which of the following physical findings can be found in scoliotic patients?
● A. Shoulder asymmetry, pelvic tilt, age length discrepancy, breast asymmetry, and trunk shift (shift of thorax to one side as compared to the pelvis)
● B. Adams forward bend test which is done by putting the feet of the patient together and forward bending with the knees straight and arms dangling which will result in a rib hump on the convex side of thoracic scoliotic curve
● C. Neurologic examination to look for abdominal cutaneous reflex, deep tendon reflexes, strength, and sensations
● D. Evidence of underlying conditions like arachnodactyly, skin pigment changes, tufts of hair, or dimpling over the spine
● E. All of the above

A

E. All of the above

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124
Q

Riser staging for assessing skeletal maturity in adolescent patient to guide decisions for bracing and timing of surgery includes following except?
● A. Stage 0 is no ossification center in the iliac crest apophysis
● B. Stages 1, 2, and 3 consist of apophysis of iliac crest up to less than 25%, 25 to 50%, and 50 to 75%, respectively
● C. Stage 4 consists of more than 75% of apophysis of the iliac crest, while stage 5 consists of complete ossification and fusion of the iliac crest apophysis
● D. Grades 0 and 1 are growing rapidly, and scoliosis curve acceleration begins in stage 0
● E. Grades 4 and 5 are growing rapidly

A

E. Grades 4 and 5 are growing rapidly

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125
Q

Which of the following are strong indications of MRI in scoliotic patients?
● A. Early-onset scoliosis in age less than 10 years
● B. Adolescent idiopathic scoliosis in males
● C. Atypical curves like thoracic levoscoliosis, kyphosis
● D. Hyperkyphosis
● E. Neurologic deficit
● F. All of the above

A

F. All of the above

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126
Q

Major curve in a scoliotic patient is the largest curve and there can be only one major curve which is almost always present at MT (main thoracic from T6 to T11, T12 disk) or TL/L (thoracolumbar/lumbar). There are other two minor curves besides the major curve, which can be structural or nonstructural. Which of the following is a structural criterion of minor curve?
● A. Side-bending residual Cobb angle more than or equal to 25 degrees
● B. A and/or T2–T5 kyphosis more than or equal to plus 20 degrees
● C. A and/or T10–L2 kyphosis more than or equal to plus 20 degrees
● D. All of the above

A

D. All of the above

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127
Q

Lenke classification is the de facto standard for classifying AIS. Following are true regarding this classification except?
● A. Type one is main thoracic
● B. Type two is double thoracic
● C. Type three is double major
● D. Type four is triple major
● E. Type five is thoracolumbar/lumbar
● F. Type six is thoracolumbar/lumbar minor thoracic

A

F. Type six is thoracolumbar/lumbar minor thoracic

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128
Q

Two basic types of braces are TLSO with a goal to wear for 18 to 23 h/d and night time TLSO with a goal to wear for 10 hours per night. Which of the following are contraindications of bracings?
● A. In skeletally mature patients
● B. Thoracic lordosis
● C. Insensate patients or insufficient neuromuscular function
● D. ± significant obesity
● E. Sanders scale 2 to 5 with curves more than or equal to 30 degrees
● F. All of the above

A

F. All of the above

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129
Q

Which of the following are the surgical fusion goals for a scoliotic patient?
● A. Correct scoliosis as much as possible
● B. Restore thoracic kyphosis
● C. Fuse all structural curves
● D. All of the above

A

D. All of the above

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130
Q

Which of the following is usually correct for adolescent idiopathic scoliosis (AIS)?
● A. Presents at 4 to 9 years of age
● B. Overwhelming male dominance
● C. Almost all with dextroscoliosis
● D. Majority are lumbar
● E. Potentially curable with Mehta serial casting

A

C. Almost all with dextroscoliosis

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131
Q

Risser system grades ossification and fusion of the iliac crest apophyses. Ossification of 25 to 50% of the iliac crest apophysis is graded as what stage?
● A. 1
● B. 2
● C. 3
● D. 4
● E. 5

A

B. 2

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132
Q

In treatment of AIS, observation is appropriate for which curves?
● A. < 25 degrees
● B. > 25 degrees
● C. < 20 degrees
● D. > 20 degrees
● E. < 30 degrees

A

A. < 25 degrees

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133
Q

Bracing is indicated in AIS for which patients?
● A. Skeletally mature
● B. Insensate patients
● C. Sander stage 1
● D. Sanders stage 3
● E. Thoracic lordosis

A

C. Sander stage 1

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134
Q

How is AdIS different from AIS?
● A. AIS presents with back and LE pain
● B. Coronal and sagittal malalignments are more common in AdIS
● C. Curves are more flexible in AdIS
● D. Sacrum needs to be included in surgical fusion in AIS
● E. In AIS, a degenerative lumbosacral fractional curve is often present as a result of degeneration

A

B. Coronal and sagittal malalignments are more common in AdIS

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135
Q

Degenerative disk disease in lumbar spine consists of age and wear related decrease in proteoglycan content of the disk, disk desiccation, tear in the annulus fibrosus, disk fibrosis, disk resorption, loss of disk space height, and osteophytes formation. What is the most powerful determinant in developing degenerative disk disease?
● A. Genetic influence and possibly other unidentified factors
● B. Cumulative effects of micro- and macrotraumas
● C. Osteoporosis
● D. Cigarette smoking
● E. Stresses on the spine like excess body weight and loss of muscle tone (primarily abdominal and paraspinal muscles)

A

A. Genetic influence and possibly other unidentified factors

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136
Q

Lumbar spinal stenosis is most common at L4–L5 and then at L3–L4 level. Symptomatic stenosis typically produces neurogenic claudication which classically is gradually progressive back and/or leg pain exacerbated by standing or walking that is relieved by sitting, lying down, or flexing at the waist. It is differentiated with vascular claudication which is usually relieved at rest regardless of position. Which of the following are contributing factors for symptomatic lumbar spinal stenosis?
● A. Congenital narrow spinal canal (short pedicle syndrome)
● B. Hypertrophy of facets and ligamentum flavum abnormalities like hypertrophy, ossification, and infolding (buckling) caused by loss of disk space height
● C. Disk bulging, herniation, collapse, and osteophyte formation
● D. Malalignment of vertebral bodies like spondylolisthesis including anterolisthesis, retrolisthesis, and olisthesis
● E. All of the above

A

E. All of the above

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137
Q

Lateral recess is the gutter alongside the pedicle, and narrowing of this space causes compression on nerve root en passant (e.g., in case of L4–L5 lateral recess narrowing, L5 nerve root will be involved) while foraminal stenosis (which can be caused by lateral disk herniation, facet hypertrophy, spondyl-
olisthesis, or disk space collapse) causes compression on the exiting nerve root as in above case L4 nerve root. Foraminal stenosis also causes loss of inverted teardrop appearance of the foramen on T1WI or T2WI sagittal MRI images. Which of the following is correct regarding boundaries of lateral recess?
● A. It is bordered anteriorly by the vertebral body
● B. It is bordered laterally by the pedicle
● C. It is bordered posteriorly by the superior articular facet of the inferior vertebral body
● D. All of the above

A

D. All of the above

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138
Q

Neurogenic claudication (NC) is thought to arise from ischemia of the lumbosacral nerve root, as a result from increased metabolic demand from exercise together with vascular compromise of the nerve root due to pressure from the surrounding structures. Following are the differences between neurogenic claudication and vascular claudication (VC) except?
● A. Distribution of pain in case of NC is dermatomal, while in case of VC, it is sclerotomal (in the distribution of muscle group)
● B. Sensory loss is in the distribution of dermatome in case of NC, while it is stocking distribution in case of VC
● C. NC pain is relieved with rest slowly often in 30 minutes, while VC pain is relieved almost immediately after taking rest
● D. Claudication distance in case of NC is variable from day to day, while it is constant in case of VC
● E. Relief of pain in case of NC is not positional, while in case of VC, it is positional

A

E. Relief of pain in case of NC is not positional, while in case of VC, it is positional

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139
Q

Normal AP diameter of lumbar spinal canal on lateral plain film (from spinolaminar line to posterior vertebral body) is 22 to 25 mm, while 15 mm is the lower limit of normal and less than 11 mm is severe lumbar stenosis. Normal ligamentum flavum thickness on CT is less than or equal to 4 to 5 mm. Which of the following statements is correct regarding dimensions of lateral recess on CT?
● A. Lateral recess height of 3 to 4 mm is border line (symptomatic if other lesions like disk bulge is also present)
● B. Less than 3 mm is suggestive of lateral recess syndrome
● C. Less than 2 mm is diagnostic of lateral recess syndrome
● D. All of the above

A

D. All of the above

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140
Q

In which of the Modic’s classification of vertebral endplate changes on MRI, there is high signal drop out (becomes low intensity) on STIR images?
● A. Modic type one (T1WI low intensity signal and T2WI high intensity signal)
● B. Modic type two (both T1WI and T2WI are high intensity signal)
● C. Modic type three (both T1WI and T2WI are low intensity signal)
● D. Modic type four
● E. None of the above

A

B. Modic type two (both T1WI and T2WI are high intensity signal)

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141
Q

Unenhanced lumbar MRI is the diagnostic test of choice to see central canal stenosis, lateral recess stenosis, foraminal stenosis, as well as juxtafacet cyst and increased fluid in the facet joint. Narrowed canal may assume a deltoid (also known as tricuspoid) shape with reduction of complete loss of CSF signal on T2WI. What other tests can be used as an adjunct to radiographic evaluation?
● A. Ankle brachial index and bicycle test to rule out vascular claudication
● B. EMG with NCV to exclude peripheral neuropathy when index of suspicion is high
● C. Bone density evaluation to see osteopenia or osteoporosis
● D. Facet blocks
● E. All of the above

A

E. All of the above

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142
Q

Spondylolisthesis is the displacement (subluxation) of one vertebral body on another in any direction. Most commonly the superior vertebral body is anterior to the posterior one. It is most common at L5 on S1, the next most common is at L4–L5. On axial MRI, it may look like a herniated disk which has
been termed as a pseudodisk. Which of the following are the types of spondylolisthesis?
● A. Type 1 is dysplastic which is also called as congenital
● B. Type 2 is isthmic which is further subdivided as lytic, elongated, and acute fracture of pars
● C. Type 3 is degenerative
● D. Type 4 is traumatic
● E. Type 5 is pathologic
● F. All of the above

A

F. All of the above

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143
Q

Surgical intervention in case of spondylolisthesis is done when symptoms become severe in spite of conservative management. The goals of surgery are pain relief, halting progression of symptoms, and possibly reversal of some existing neurologic deficit. Surgical options include posterior decompression with or without fusion which may include posterior lumbar interbody fusion or transforaminal lumbar interbody fusion. Which of the following are the situations where a fusion should be considered
in addition to direct or indirect decompression of the nerves?
● A. Spondylolisthesis (especially grade more than 1)
● B. Symptomatic sagittal imbalance or degenerative scoliosis
● C. Dynamic instability on flexion/extension lateral lumbar spine X-rays
● D. Expectation that decompression will destabilize the spine
● E. Multiple recurrent herniated disk
● F. All of the above

A

F. All of the above

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144
Q

Gill procedures include which of the following?
● A. Radical decompression of nerve root including removal of the loose posterior elements and total facetectomy
● B. Posterolateral or interbody fusion
● C. Fusion rate may be enhanced with the use of internal fixation, for example, transpedicular screw rod fixation
● D. All of the above

A

D. All of the above

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145
Q

What is the most powerful determinant in developing degenerative spine disease (DSD)?
● A. Genetic influence
● B. Cumulative effects of micro-trauma and macro-trauma to the spine
● C. Osteoporosis
● D. Cigarette smoking
● E. Excess body weight

A

A. Genetic influence

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146
Q

Lumbar spinal stenosis is caused by hypertrophy of facets and ligamentum flavum and may be exacerbated by spondylolisthesis. It occurs most commonly at which level?
● A. L1–L2
● B. L2–L3
● C. L3–L4
● D. L4–L5
● E. L5–S

A

D. L4–L5

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147
Q

What is the prototypical symptom of lumbar spinal stenosis (LSS)?
● A. Neurogenic claudication
● B. LE spasticity
● C. Sphincter disturbance
● D. Low back ache
● E. Weakness of LE

A

A. Neurogenic claudication

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148
Q

What is the clinical feature distinguishing neurogenic claudication from vascular claudication?
● A. Pain in the distribution of muscle group with common vascular supply (sclerotomal)
● B. Relief with rest is slow (often > 30 mins), variable, usually positional (stooped posture or sitting often required)
● C. Claudicating distance is constant every day
● D. Sensory loss in stocking distribution
● E. Reliably reproduced with fixed amount of exercise

A

B. Relief with rest is slow (often > 30 mins), variable, usually positional (stooped posture or sitting often required)

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149
Q

What is the normal AP diameter of lumbar spinal canal on lateral plain film?
● A. 11 to 15 mm
● B. 15 to 18 mm
● C. 18 to 22 mm
● D. 22 to 25 mm
● E. 25 to 28 mm

A

D. 22 to 25 mm

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150
Q

Anterior subluxation of one vertebral body (VB) on another is spondylolisthesis. It occurs most commonly at which level?
● A. L1–L2
● B. L2–L3
● C. L3–L4
● D. L4–L5
● E. L5–S1

A

E. L5–S1

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151
Q

Commonly a true disk herniation occurs with relation to spondylolisthesis at which level?
● A. At the same level
● B. One level below
● C. One level above
● D. Two levels above
● E. Two levels below

A

C. One level above

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152
Q

According to the Meyerding grade, spondyloptosis is listhesis of what percent?
● A. > 25%
● B. 25 to 50%
● C. 50 to 75%
● D. 75 to 100%
● E. > 100%

A

E. > 100%

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153
Q

On spine CT, what is the lateral recess height diagnostic of lateral recess syndrome?
● A. 7 mm
● B. 5 mm
● C. 4 mm
● D. 3 mm
● E. 1 mm

A

E. 1 mm

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154
Q

In isthmic spondylolisthesis, lesions without sclerosis that show increased uptake on bone scan and MRI high signal changes on STIR may be treated with which of the following?
● A. Boston brace
● B. Steroid
● C. Injection therapy
● D. Crutches
● E. Orthopedic mattress

A

A. Boston brace

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155
Q

Which of the following is primarily an extension limiting procedure for lumbar spine that can be used as a stand-alone procedure?
● A. Laminectomy
● B. Anterior lumbar interbody fusion
● C. Transforaminal lumbar interbody fusion
● D. Oblique lumbar interbody fusion
● E. Interspinous spacer

A

E. Interspinous spacer

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156
Q

A patient presents with backache radiating to lower limbs which increases during walking. This patient has obvious spinal deformity with scoliosis, forward flexion at the wrist, and walking with knees bent. This patient is more than 60 years of age. Standing coronal view X-ray was done which showed Cobb
angle of more than 10 degrees. What is the most probable diagnosis in this case?
● A. Adult degenerative spine disease
● B. Adolescent idiopathic scoliosis
● C. Adult idiopathic scoliosis
● D. Adult spinal deformity
● E. None of the above

A

A. Adult degenerative spine disease

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157
Q

SRS-Schwab classification of adult degenerative spinal deformity has which of the following parameters?
● A. Coronal curve types
● B. Sagittal modifiers
● C. Global alignment
● D. Pelvic tilt
● E. All of the above

A

E. All of the above

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158
Q

Treatment options for adult degenerative scoliosis are based on clinical symptoms and include the following except?
● A. Observation only
● B. Focal decompression
● C. Surgical correction of deformity and stability using traditional open surgery (decompression by laminectomy, PLIF, TLIF, pedicle screw/rod fixation), minimal invasive spine surgery, and combined (both open and MIS)
● D. Anterior corpectomy and cage fixation
● E. None of the above

A

D. Anterior corpectomy and cage fixation

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159
Q

Summary for spinopelvic alignment objectives include the following except?
● A. LL = PI ± 9 degrees
● B. PT less than 20 degrees
● C. PSVL and SSV should be less than 30 degrees
● D. SVA less than 5 cm

A

C. PSVL and SSV should be less than 30 degrees

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160
Q

Which of the following is Schwab grade 3 of surgical spine osteotomies?
● A. Resection of the inferior facet and joint capsule
● B. Resection of the superior and inferior facets, ligamentum flavum, and possible lamina and spinous process
● C. Partial wedge resection of the vertebral body and the posterior elements with the pedicles
● D. Partial wedge resection of the vertebral body and the posterior elements with the pedicles plus inclusion of at least a portion of the endplate and one adjacent disk
● E. Complete removal of the vertebra and both adjacent disks

A

C. Partial wedge resection of the vertebral body and the posterior elements with the pedicles

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161
Q

How much lumbar lordosis can be obtained by Schwab grade 1 osteotomy plus ACR?
● A. 1 degree
● B. 6 degrees
● C. 5 to 10 degrees
● D. 16 degrees
● E. 30 to 40 degrees

A

D. 16 degrees

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162
Q

Morbid obesity (BMI more than 40) doubles the risk of complications of all types including cardiac, renal, pulmonary, and wound complications with spine surgery, and mortality is increased by how much?
● A. Doubled
● B. Tripled
● C. Four times increased
● D. Five times increased
● E. None of the above

A

B. Tripled

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163
Q

Pedicle subtraction can increase LL by 30 to 40 degrees. What is the Schwab grade?
● A. Grade 1
● B. Grade 2
● C. Grade 3
● D. Grade 4
● E. Grade 5

A

C. Grade 3

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164
Q

Coronal balance is measured on AP standing scoliosis X-ray. A plumb line is drawn straight down from the center of the C7 vertebral body. There is coronal imbalance if this falls from midline of the sacrum by more than what?
● A. 2 cm
● B. 3 cm
● C. 4 cm
● D. 5 cm
● E. 6 cm

A

C. 4 cm

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165
Q

CT scan in case of adult degenerative scoliotic patient can provide which of the following information?
● A. Any fusions (spontaneous or surgical)
● B. Vacuum disk (which imply hypermobility)
● C. Calcifications (in herniated disks, ligamentum flavum)
● D. For obtaining measurements for surgical instrumentation
● E. All of the above

A

E. All of the above

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166
Q

Before surgery for adult spinal deformity (ASD), surgeons use teriparatide for how long to rapidly increase the strength of osteoporotic bone?
● A. 2 weeks
● B. 4 weeks
● C. 6 weeks
● D. 3 months
● E. 6 months

A

D. 3 months

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167
Q

Standing scoliosis X-ray must image from C7 down to what level?
● A. T7
● B. Midthoracic level
● C. Thoracolumbar junction
● D. L1
● E. Femoral heads

A

E. Femoral heads

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168
Q

The degree of curve rigidity after scoliosis surgery can be determined with which of the following?
● A. Dynamic standing scoliosis X-ray
● B. Flexion–extension X-rays
● C. CT scan
● D. CT myelogram
● E. MRI with contrast

A

A. Dynamic standing scoliosis X-ray

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169
Q

Pre- and postoperative standing scoliosis X-rays help to confirm that alignment objectives are achieved. Following views are required for adolescent idiopathic scoliosis (AIS) except?
● A. Standing coronal
● B. Lateral
● C. Left bending
● D. Right bending
● E. Sagittal

A

E. Sagittal

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170
Q

According to Schwab’s classification of surgical osteotomies, a complete removal of the vertebra and both adjacent disks and rib resections extended over multiple vertebral levels is what grade?
● A. Zero
● B. II
● C. III
● D. V
● E. VI

A

E. VI

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171
Q

Anterior lumbar interbody fusion (ALIF) is best for lumbar level where the great vessels tend not to interfere with the access, and where every degree of correction produces a more significant amount of improvement in vertical alignment. Which level is this?
● A. L1–L2
● B. L2–L3
● C. L3–L4
● D. L4–L5
● E. L5–S1

A

E. L5–S1

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172
Q

Standing scoliosis X-rays provide information about scoliosis and which of the following?
● A. Sagittal balance
● B. Cobb’s angle
● C. Anterolisthesis
● D. Retrolisthesis
● F. Dynamic stability

A

A. Sagittal balance

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173
Q

A patient presents with pain in the back, joint pain, and multiple nerve root compressive symptoms (due to expansion of woven bone, osteoid tissue). Lab work shows elevated alkaline phosphatase and urinary hydroxyproline. CT of spine shows hypertrophic changes at the facet joints and X-rays show cortical thickening, sclerotic changes, and osteolytic areas. Which of the following is correct regarding Paget’s disease?
● A. It is a disorder of osteoclasts causing increased rate of bone resorption
● B. Reactive osteoblastic activity with overproduction of new, weaker, woven bone
● C. Initial hot phase
● D. Cold phase in the last
● E. All of the above

A

E. All of the above

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174
Q

A patient presents to neurosurgical OPD with complaints of nonradiating low back pain, morning back stiffness, hip pain with swelling, which is exacerbated by inactivity and improved with exercise. X-ray of this patient shows bridging of syndesmophytes between vertebral bodies creating the so-called bamboo spine appearance and sacroiliitis as well. RA factor in serum of this patient is negative. This patient is diagnosed using Modified New York criteria. What is the diagnosis in this case?
● A. Rheumatoid arthritis
● B. Reiter’s syndrome
● C. Forestier’s disease
● D. Ankylosing spondylitis
● E. Metastatic prostate cancer

A

D. Ankylosing spondylitis

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175
Q

The most common surgical intervention in ankylosing spondylitis is orthopedic total hip arthroplasty, while the most frequent fracture site in ankylosing spondylitis is which of the following?
● A. Lumbar spine
● B. Thoracolumbar spine
● C. Cervical spine
● D. Thoracic spine
● E. Lumbar sacral junction

A

C. Cervical spine

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176
Q

A 55-year-old male patient presents to OPD with signs of myelopathy and positive Hoffmann’s sign. His MRI shows a hypointense signal from C3 to C6 level on T2WI which is obliterating CSF signal with cord compression anteriorly. His CT of cervical spine shows calcified anterior longitudinal ligament behind c4, c5, and c6 vertebral bodies. What is the most common location of OPLL in spine (which is 70 to 75%)?
● A. Cervical
● B. Thoracic
● C. Lumbar
● D. Both cervical and thoracic
● E. None of the above

A

A. Cervical

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177
Q

Which of the following is included in the pathological classification of ossified posterior longitudinal ligament?
● A. Segmental (39%), confined to the space behind the vertebral bodies
● B. Continuous (17%), extending from vertebral body to vertebral body spanning the disk space
● C. Mixed (25%), combined elements of both A and B
● D. Other variants (5%), a rare type of OPLL that is contiguous with the end plates and is confined to the disk space
● E. All of the above

A

E. All of the above

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178
Q

Which of the following statements is correct regarding Nurick grade of disability from cervical spondylosis?
● A. Grade 0: signs or symptoms of root involvement without myelopathy
● B. Grade 1: myelopathy but no difficulty in walking
● C. Grade 2: slight difficulty in walking, able to work
● D. Grade 3: difficulty in walking but not needing assistance, unable to work full time
● E. Grade 4: able to walk only with assistance or walker
● F. Grade 5: chair bound or bed ridden
● G. All of the above

A

G. All of the above

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179
Q

A patient presents to neurosurgical OPD with complaints of backache and anterior wedging of at least 5 degrees of more than or equal to three adjacent thoracic vertebral bodies. Associated findings in Scheuermann’s kyphosis include the following except?
● A. End plate irregularities
● B. Posterior narrowing of disk space
● C. Schmorl’s nodes
● D. Scoliosis
● E. Spondylolysis in 50%

A

B. Posterior narrowing of disk space

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180
Q

Rheumatoid arthritis (RA) most commonly involves cervical spine (in 44–88% cases of RA) which can be atlantoaxial subluxation, basilar impression, or subaxial subluxation. Which of the following is included in the Ranawat classification of myelopathy in RA?
● A. Class 1: no neural deficit
● B. Class 2: subjective weakness + hyperreflexia + dysesthesia
● C. Class 3: objective weakness plus long tract signs
● D. Class 3A, ambulatory, and class 3 B, quadriparetic and nonambulatory
● E. All of the above

A

E. All of the above

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181
Q

Spinal cord infarction can be due to atherosclerosis of radicular arteries in elderly patients, clamping of aorta during surgery, trauma, hypotension, aortic dissection, or embolization of spinal arteries. Acute anterior spinal cord syndrome, which results in motor paralysis below the level of injury, loss of pain
and temperature with preserved vibratory and position sense, and loss of sphincter control, is because of involvement of which artery?
● A. Anterior spinal artery
● B. Posterior spinal artery
● C. Radicular arteries
● D. Abdominal aorta
● E. None of the above

A

A. Anterior spinal artery

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182
Q

Noncontrast CT scan is probably the most sensitive test for detecting pneumorrhachis as well as air in other body compartments. What are the surgical indications of pneumorrhachis (air in the spinal canal)?
● A. Intracranial hypo-/hypertension refractory to medical management
● B. Significant or persistent CSF leak
● C. Evidence of unidirectional ball valve (tension pneumorrhachis) near at-risk nervous tissue
● D. Herniation or serious injury of adjacent structures (for example, lungs) into the spinal cord
● E. All of the above

A

E. All of the above

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183
Q

Paget’s disease may be asymptomatic or present with pain, radiculopathy, and compression of cranial nerves as they pass through skull foramina. Which of the following is the most commonly affected cranial nerve?
● A. III
● B. VI
● C. VII
● D. VIII
● E. X

A

D. VIII

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184
Q

Paget’s disease depicts ivory bone. The treatment of the disease includes calcitonin derivatives that mainly act by which of the following mechanisms?
● A. Osteoclast activity reduction
● B. Osteoclast activity stimulation
● C. Osteoblast activity reduction
● D. Osteoblast activity stimulation
● E. Inhibition of intestinal calcium absorption

A

A. Osteoclast activity reduction

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185
Q

Ankylosing spondylitis gives rise to bamboo spine, Andersen lesions, and kyphosis. By definition, which joint is always affected?
● A. Scapulohumeral joint
● B. Sacroiliac joint
● C. Ankle joint
● D. Small joints at wrist
● E. Costovertebral

A

B. Sacroiliac joint

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186
Q

Which of the following is a test for monitoring ongoing physical therapy and is done by measuring distraction between skin marks on the back before and after forward flexion to detect reduced mobility of the spine due to fusion?
● A. Schober test
● B. Patrick test
● C. Lhermitte sign
● D. Hoover test
● E. Ankylosing test

A

A. Schober test

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187
Q

What is the most common level affected by ossified posterior longitudinal ligament?
● A. Cervical
● B. Midthoracic
● C. Thoracolumbar
● D. Lumbar
● E. Lumbosacral

A

A. Cervical

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188
Q

There are four patterns of ossified posterior longitudinal ligament. When it extends from vertebral body to vertebral body, spanning disk space, it is which pattern?
● A. Segmental
● B. Skipping
● C. Continuous
● D. Punctate
● E. Mixed

A

C. Continuous

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189
Q

Which is the best test for demonstrating and accurately diagnosing ossified posterior longitudinal ligament?
● A. X-ray
● B. CT with coronal reconstruction
● C. CT myelogram
● D. MRI with contrast
● E. Bone scan

A

C. CT myelogram

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190
Q

According to Nurick grade of disability from cervical spondylosis, being able to walk only with assistance or walker is which grade?
● A. I
● B. II
● C. III
● D. IV
● E. V

A

D. IV

191
Q

Diffuse idiopathic skeletal hyperostosis (DISH) is characterized in spine by flowing formation of which of the following?
● A. Anterior longitudinal ligament
● B. Posterior longitudinal ligament
● C. Disk desiccation
● D. Osteophytes
● E. Schmorl’s nodes

A

D. Osteophytes

192
Q

In Scheuermann’s kyphosis, when the apex is above T8, the patient can be treated with which of the following?
● A. SOMI brace
● B. Miami J
● C. Philadelphia collar
● D. Milwaukee brace
● E. Abdominal binder

A

D. Milwaukee brace

193
Q

Some surgeons do not operate if the maximal dens–C1 distance is how much?
● A. < 2 cm
● B. < 4 cm
● C. < 6 mm
● D. < 8 mm
● E. < 10 mm

A

C. < 6 mm

194
Q

The direct effects of rheumatoid arthritis (RA) on the subaxial spine involves which of the following?
● A. Facet joints posteriorly
● B. Disk space anteriorly
● C. Ligamentous hypertrophy
● D. End plate erosion
● E. Pars defect

A

A. Facet joints posteriorly

195
Q

What is the incidence of atlantoaxial subluxation (AAS) in Down syndrome (DS)?
● A. 10%
● B. 20%
● C. 30%
● D. 40%
● E. 50%

A

B. 20%

196
Q

In Down syndrome, what is the recommended management for asymptomatic atlantoaxial subluxation (AAS) seen on lateral C-spine X-ray with ADI ≤ 4.5 mm and PADI ≥ 14 mm?
● A. No need for further testing
● B. Cervical MRI
● C. Surgical fusion
● D. Prohibit high-risk activity
● E. CT of C spine

A

A. No need for further testing

197
Q

With spontaneous SEH, recovery of neurologic deficit without surgery is rare. Improvement is seen when decompression is done within how long?
● A. 6 hours
● B. 12 hours
● C. 24 hours
● D. 48 hours
● E. 72 hours

A

E. 72 hours

198
Q

What is the Ranawat class of a patient with subjective weakness + hyperreflexia + dysesthesia?
● A. I
● B. II
● C. III
● D. IV
● E. V

A

B. II

199
Q

Anterior atlantodental interval (ADI) gives information about the stability of the C1–C2 joint. The normal ADI in adults is less than what?
● A. 11 mm
● B. 10 mm
● C. 7 mm
● D. 5 mm
● E. 3 mm

A

E. 3 mm

200
Q

Patients with paralysis from atlantoaxial subluxation in rheumatoid arthritis do not recover with surgery if the preoperative posterior atlantodental interval (PADI) is less than what?
● A. 25 mm
● B. 25 mm
● C. 15 mm
● D. 14 mm
● E. 10 mm

A

E. 10 mm

201
Q

For transoral odontoidectomy without splitting the mandible, the patient must be able to open the mouth by more than how much?
● A. 5 mm
● B. 10 mm
● C. 15 mm
● D. 20 mm
● E. 25 mm

A

E. 25 mm

202
Q

Cervicomedullary angle is the angle between a line drawn through the long axis of the medulla on a sagittal MRI and a line drawn through the cervical spinal cord. It correlates with signs of cervicomedullary compression, myelopathy, or C2 radiculopathy when it is less than how much degrees?
● A. 360
● B. 275
● C. 185
● D. 155
● E. 135

A

E. 135

203
Q

Which of the following is included in the“American/English/French Connection” classification systems of spinal AVMs?
● A. Type 1: Dural AVM (AV fistula) is the most common type of SVM (80%) in adults. This is fed by a radicular artery which forms an AV shunt at the dural root sleeve and drains into an engorged vein. It is further divided into type 1A (single arterial feeder) and type 1B with two or more arterial feeders
● B. Type 2: Also known as spinal glomus AVM it is intramedullary and constitutes 15 to 20% of all AVMs. It is fed by medullary arteries and has worse prognosis than dural AVM
● C. Type 3: Also known as juvenile spinal AVM it occupies the entire cross section of the cord and invades the vertebral body which may cause scoliosis
● D. Type 4: It is intradural perimedullary AVM which is further divided into three types
● E. All of the above

A

E. All of the above

204
Q

Which of the following is incorrect regarding Merland’s subclassification of type 4 (perimedullary) AV fistulas?
● A. Subtype 1 with single arterial feeder, single AVF, and slow ascending perimedullary venous system
● B. Subtype 2 with multiple arterial supply, multiple AVF, and slow ascending perimedullary venous system
● C. Subtype 3 with multiple arterial feeders, single giant AVF, and giant venous ectasia with rapid venous drainage
● D. Subtype 4 with multiple arterial feeders, multiple AVF, and multiple fast draining veins
● E. All of the above

A

E. All of the above

205
Q

Which of the following statements is correct regarding treatment of dural AVF?
● A. Type 1 is mostly treated with surgery
● B. Type 2B is preferably treated with surgery while type 2A is more comfortably treated by neuroradiologic procedures like embolization
● C. Type 3 is treated conservatively
● D. Type 4: Subtype 1 on filum terminale can be treated surgically but on conus medullaris it is difficult to treat surgically. While embolization is difficult for subtype 4. Subtype 3 is treated with embolization
● E. All of the above

A

D. Type 4: Subtype 1 on filum terminale can be treated surgically but on conus medullaris it is difficult to treat surgically. While embolization is difficult for subtype 4. Subtype 3 is treated with embolization

206
Q

Following are correct regarding spinal meningeal cyst types and their treatment except?
● A. Type 1 is extradural meningeal cysts without spinal nerve root fibers which can be extradural meningeal/arachnoid cysts (type 1A) or sacral meningocele (type 1B) and it is treated by closing the ostium between the cyst and subarachnoid space
● B. Type 2 is extradural meningeal cysts with spinal nerve root fibers (Tarlov perineural cyst, spinal nerve root diverticulum) which is treated by partially resecting cyst wall and oversewing the cyst wall or excising the cyst and involved nerve root
● C. Type 3 is spinal intradural meningeal cyst (intradural arachnoid cyst) which is excised completely unless dense fibrous adhesion prevents this in which case the cyst is marsupialized
● D. Type 4 is both intradural and extradural, which is managed conservatively
● E. None of the above

A

D. Type 4 is both intradural and extradural, which is managed conservatively

207
Q

A 40-year-old male patient presents with thoracic pain followed by lower extremity symptoms and then myelopathy. This patient also has upper extremity numbness and paresthesias. MRI of thoracic spine of this patient shows indentation or
displacement of the spinal cord which is “scalpel sign.” This patient has syringomyelia as well. What is the most likely diagnosis in this case?
● A. Spinal arachnoid cyst
● B. Spinal arachnoid web
● C. Spinal meningeal cyst
● D. Syringomyelia
● E. Myelomalacia

A

B. Spinal arachnoid web

208
Q

A patient presents with progressive neurologic deterioration over months to years with upper limbs being affected more than the lower limbs. Syringomyelia is also known as syrinx which is cystic cavitation of the spinal cord. What is the most common cause of syrinx formation?
● A. Chari type 1 malformation
● B. Post inflammatory including TB or fungal meningitides or
postoperative meningitis
● C. Postoperative syringomyelia
● D. Basilar impression with constriction at the foramen magnum
● E. Spinal tumors

A

A. Chari type 1 malformation

209
Q

Major theories of formation of cyst include the following except?
● A. Hydrodynamic (water hammer) theory of Gardner: systolic pulsations are transmitted with each heartbeat from the intracranial cavity to the central canal
● B. William’s (craniospinal dissociation) theory: maneuvers that raise CSF pressure (Valsalva, coughing) cause hydrodissection through the spinal cord tissue
● C. Heishima maneuver theory which states that obstruction in the path of CSF causes back pressure which results in formation of syrinx
● D. Heiss-Oldfield theory: occlusion at the foramen magnum causes CSF pulsations during cardiac systole to be transmitted through the Virchow-Robin spaces, which increases the extracellular fluid, which coalesces to form a syrinx

A

C. Heishima maneuver theory which states that obstruction in the path of CSF causes back pressure which results in formation of syrinx

210
Q

A patient presents with suspended (cape) dissociated sensory loss (loss of pain and temperature sensation with preserved touch and joint position sense). This patient also has pain in the cervical and occipital region and lower motor
weakness of the hand and arm. This patient has low attenuation area within the cord seen on either plain CT or myelogram, and MRI shows hyperintense area within the cord. What is the most likely diagnosis in this patient?
● A. Tumor cyst
● B. Syringomyelia
● C. Central spinal canal
● D. Ventriculus terminalis
● E. None of the above

A

B. Syringomyelia

211
Q

The central canal is present within the spinal cord at birth and normally gradually involutes with age. Persistence of the cyst is the normal variant. Which of the following are the differences between syringomyelia and central spinal canal?
● A. Central spinal canal is fusiform or linear on sagittal MRI
● B. Central spinal canal is less than or equal to 4 mm in maximal width while it is wider in case of syringomyelia
● C. Central spinal canal is singular or may be several discontinuous regions in the rostral caudal direction
● D. Central canal is perfectly round in cross section and centrally located on axial MRI
● E. There should be no contrast enhancement in case of central spinal canal if contrast is given
● F. All of the above

A

F. All of the above

212
Q

Treatment of syrinx consist of treating the underlying pathology to re-establish subarachnoid CSF flow which includes posterior decompression in case of posterior anomalies like Chiari malformation or decompression if feasible if a site of compression or blockage or tethering is identified. Syrinx
shunts indications include syrinx diameter more than 3 to 4 mm with no identifiable cause or blockage that cannot be circumvented due to thick adhesions. What is the syrinx catheter option?
● A. K tube
● B. T tube
● C. M tube
● D. B tube
● E. Both A and B

A

E. Both A and B

213
Q

In the “American/English/French Connection” classification for spinal vascular malformations, an AVM fed by the radicular artery, which forms an AV shunt at the dural root sleeve, and drains into an engorged spinal vein on the posterior cord is what?
● A. Dural AVM
● B. Intradural AVM
● C. Juvenile spinal AVM
● D. Spinal glomus
● E. Intramedullary

A

A. Dural AVM

214
Q

An intradural perimedullary AVM where there is a direct fistula between anterior spinal artery or artery of Adamkiewicz and draining veins is which subtype of intradural AVMs?
● A. I
● B. II
● C. III
● D. IV
● E. V

A

D. IV

215
Q

Spetzler classification of spinal AVMs has also added which lesions not included in the “American/English/French Connection” and Hôpital Bicêtre classifications?
● A. Neoplastic lesions
● B. Dorsal malformations
● C. Intramedullary lesions
● D. Extramedullary lesions
● E. Intradural fistulas

A

A. Neoplastic lesions

216
Q

An acute or subacute neurologic deterioration in a patient with a spinal venous malformation (SVM) without evidence of hemorrhage is what?
● A. Coup de poignard of Michon
● B. Foix-Alajouanine syndrome
● C. Artery of Bernasconi & Cassinari
● D. Subacute subarachnoid sclerosis

A

B. Foix-Alajouanine syndrome

217
Q

Spinal intradural meningeal cysts are what type?
● A. I
● B. IIA
● C. IIB
● D. IIC
● E. III

A

E. III

218
Q

What is the most common cause of secondary syringomyelia?
● A. Chiari I malformation
● B. Chiari II malformation
● C. Dandy Walker syndrome
● D. Down syndrome
● E. Rheumatoid arthritis

A

A. Chiari I malformation

219
Q

The juxtafacet cyst (JFC) is most commonly present in which of the following?
● A. Cervical
● B. Cervicothoracic junction
● C. Thoracic
● D. Lumbar
● E. Sacral

A

D. Lumbar

220
Q

What is the treatment of choice for syringomyelia associated with Chiari malformation?
● A. Syringostomy
● B. Subarachnoid–subarachnoid shunt
● C. Lumboperitoneal shunt
● D. Posterior decompression
● E. Cordectomy

A

D. Posterior decompression

221
Q

What is the preferred treatment for syringomyelia secondary to tuberculous meningitis?
● A. Syringostomy
● B. Subarachnoid–subarachnoid shunt
● C. Lumboperitoneal shunt
● D. Posterior decompression
● E. Cordectomy

A

B. Subarachnoid–subarachnoid shunt

222
Q

Hirayama disease is a motor neuron disease predominantly affecting which spinal segments?
● A. c3–c5
● B. c5–c8
● C. c8–t1
● D. t1–t4
● E. t4–t6

A

C. c8–t1

223
Q

Trauma is the most common cause of subarachnoid hemorrhage. Which of the following statements are correct regarding aneurysmal subarachnoid hemorrhage?
● A. 10 to 15% of patients die before reaching medical care
● B. Mortality is 10% within first few days of aneurysmal subarachnoid hemorrhage
● C. 30-day mortality rate was 46% in one series and in others over half the patients died within 2 weeks of their subarachnoid hemorrhage
● D. Among patients surviving the initial hemorrhage treated without surgery, rebleeding is the major cause of morbidity and mortality, the risk of which is 15 to 20% within 2 weeks. The goal of early surgery is to reduce this risk
● E. About 30% of survivors have moderate to severe disability, with rates of persistent dependence estimated between 8 and 20% in population-based studies
● F. All of the above

A

F. All of the above

224
Q

Etiologies of subarachnoid hemorrhage include trauma and spontaneous subarachnoid hemorrhage (which includes ruptured intracranial aneurysms which includes 75 to 80% of spontaneous subarachnoid hemorrhage, cerebral AVM, certain
vasculitides, rarely due to tumor or cerebral artery dissection). Which of the following are the risk factors of aneurysmal subarachnoid hemorrhage?
● A. Behavioral including hypertension, cigarette smoking, alcohol abuse, sympathomimetic drugs such as cocaine or amphetamines
● B. Gender and race
● C. History of cerebral aneurysm (unruptured aneurysm, bottleneck shape of aneurysm, and increased ratio of size of aneurysm to parent vessel)
● D. Family history of aneurysms
● E. Genetic syndromes like autosomal dominant polycystic kidney disease or type 4 Ehlers Danlos syndrome
● F. All of the above

A

F. All of the above

225
Q

A patient presents with sudden onset of severe headache usually with vomiting, syncope, neck pain, and photophobia. All of the following are causes of coma in a patient with aneurysmal subarachnoid hemorrhage except?
● A. Low ICP
● B. Damage to brain tissue due to intraparenchymal hemorrhage
● C. Hydrocephalus
● D. Diffuse ischemia
● E. Seizure

A

A. Low ICP

226
Q

What is the gold standard test for evaluation of cerebral aneurysms?
● A. CT angiography of brain
● B. MRA
● C. Catheter angiogram
● D. LP
● E. Plain CT of brain

A

C. Catheter angiogram

227
Q

Plain CT of brain can predict aneurysm location based on the pattern of blood in 78% of cases while other findings that can be seen on plain CT of brain include ventricular size, hematoma, and amount of blood in cisterns and fissures. What is the size of aneurysms that can be detected on CT angiography with 98% sensitivity and 100% specificity?
● A. More than 1 mm
● B. More than 2 mm
● C. More than 3 mm
● D. More than 4 mm
● E. More than 5 mm

A

C. More than 3 mm

228
Q

Lowering the CSF pressure with an LP may possibly precipitate rebleeding by increasing the transmural pressure (the pressure across the aneurysmal wall) which is prevented using less than or equal to 20-gauge spinal needle and removing only a small amount of CSF. Which of the following are the findings that can be obtained using an LP?
● A. Opening pressure usually elevated with subarachnoid hemorrhage
● B. Nonclotting bloody fluid that does not clear with sequential collection tubes and xanthocromia which is yellow coloration of CSF supernatant due to the lysis of RBCs
● C. RBC count is usually more than 1,00,000/mm cube in subarachnoid hemorrhage
● D. Elevated protein due to blood breakdown products
● E. All of the above

A

E. All of the above

229
Q

The size of aneurysm dome, neck size of aneurysm, and dome to neck ratio can be obtained using a catheter angiogram. Narrow necks less than 5 mm are ideal for coiling. What is the dome to neck ratio that is associated with higher rate of successful coil occlusion?
● A. More than 1
● B. More than 1.5
● C. More than 2
● D. More than 2.5
● E. More than 3

A

C. More than 2

230
Q

Grades 1 and 2 of Hunt and Hess classification are operated upon as soon as the aneurysm is diagnosed while grades more than or equal to 3 are managed until the condition improves to grade 1 or 2. Exception to this include life-threatening hematoma or multiple bleeds which are operated upon regardless of any grade. Which of the following statements is correct regarding Hunt and Hess classification of SAH?
● A. Grade 1 is asymptomatic or mild headache and slight nuchal rigidity
● B. Grade 2 is cranial nerve 3 or 6 palsy with moderate-to-severe headache and nuchal rigidity
● C. Grade 3 is mild focal deficit, lethargy, or confusion
● D. Grade 4 is stupor, moderate-to-severe hemiparesis, and early decerebrate rigidity
● E. Grade 5 is deep coma, decerebrate rigidity, and moribund appearance
● F. All of the above

A

F. All of the above

231
Q

Which of the following statements is incorrect regarding WFNS SAH grading?
● A. Grade 0 is intact patient
● B. Grade 1 is GCS score 15 without any major focal deficit
● C. Grade 2 is GCS score 13–14 without any major focal deficit
● D. Grade 3 is GCS score 13–14 with major focal deficit
● E. Grade 4 is GCS score 7–12 with or without major focal deficit
● F. Grade 5 is GCS score 3–6 without major focal deficit

A

F. Grade 5 is GCS score 3–6 without major focal deficit

232
Q

Acute hydrocephalus (HCP) after SAH can result from blood interfering with CSF flow through the sylvian aqueduct, 4th ventricle, or subarachnoid spaces and/or reabsorption at the arachnoid granulations. What is the best management option
for acute hydrocephalus after SAH with poor Hunt and Hess grade?
● A. Urgent ventriculostomy
● B. Keeping the ICP in the range of 15 to 25 mmHg in case of EVD to avoid rapid pressure reduction to decrease the risk of IVC-induced aneurysmal bleeding
● C. Draining CSF slowly after performing an EVD to avoid rapid changes in transmural pressure
● D. Ventriculostomy can cause improvement in 80% of patients with acute hydrocephalus after SAH who are having poor Hunt and Hess grading (grade 4 or 5)
● E. All of the above

A

E. All of the above

233
Q

A 70-year-old male presented in the emergency with sudden-onset severe headache followed by loss of consciousness. CT of brain revealed subarachnoid hemorrhage (SAH). What is the most common cause of SAH?
● A. Trauma
● B. Hypertension
● C. Vascular malformations
● D. Telangiectasia
● E. Aneurysm

A

A. Trauma

234
Q

A 34-week pregnant woman was brought to the emergency with history of sudden severe headache and altered sensorium. What is the risk of aneurysmal SAH in pregnancy?
● A. 2-fold
● B. 4-fold
● C. 5-fold
● D. 10-fold
● E. No risk

A

E. No risk

235
Q

A 45-year-old female presented in the emergency with sudden loss of consciousness. She has a family history of aneurysms. CT of brain showed SAH. Fundoscopy revealed ocular hemorrhages within vitreous humor. What is this condition is called?
● A. Bouchard syndrome
● B. Turcot syndrome
● C. Terson syndrome
● D. Amyloid angiopathy
● E. Gardener syndrome

A

C. Terson syndrome

236
Q

A middle-aged female was referred for definitive treatment for aneurysmal SAH. What is the gold standard test for evaluation of cerebral aneurysms?
● A. CT with contrast
● B. Magnetic resonance arteriogram
● C. Lumbar puncture and CSF examination for xanthochromia
● D. Catheter angiogram
● E. Magnetic resonance venogram

A

D. Catheter angiogram

237
Q

A middle-aged man presented with sudden-onset headache, altered level of consciousness, and right hemiparesis. On examination, the patient was stuporous with signs of early decerebrate rigidity. What is the Hunt and Hess grade in this case?
● A. 0
● B. 1
● C. 2
● D. 3
● E. 4

A

E. 4

238
Q

A middle-aged female presented with sudden-onset headache followed by loss of consciousness. On examination, GCS was E1V1M2 with right, dilated, nonreactive pupil and left hemiplegia. What is the WFNS grade for this case?
● A. 1
● B. 2
● C. 3
● D. 4
● E. 5

A

E. 5

239
Q

When a ventriculostomy is used, it is recommended to keep ICP in what range?
● A. 7 to 9 mmHg
● B. 9 to 12 mmHg
● C. 12 to 15 mmHg
● D. 15 to 25 mmHg
● E. 25 to 28 mmHg

A

D. 15 to 25 mmHg

240
Q

Which of the following is safe in management of SAH during pregnancy?
● A. Nimodipine
● B. Mannitol
● C. Iodinated contrast for angiography
● D. Nitroprusside
● E. Phenytoin

A

C. Iodinated contrast for angiography

241
Q

Initial management concerns after aneurysmal SAH (aSAH) include rebleeding, hydrocephalus, delayed cerebral ischemia, hyponatremia with hypovolemia, DVT and pulmonary embolism seizures, and reduced cerebral oxygen delivery. What are the initial management steps that are needed to reduce these risks after aSAH?
● A. Administration of oral nimodipine
● B. Maintaining euvolemia and normal circulating blood volume
● C. Control of blood pressure by keeping the systolic blood pressure below 160 mmHg
● D. Optimizing cerebral blood flow and keeping normal ICP
● E. All of the above

A

E. All of the above

242
Q

Methods that may be used to augment cerebral oxygen delivery includes all of the following except?
● A. Optimizing cerebral blood flow by avoiding induced hypertension, avoiding hypotension, and maintaining euvolemia and normal ICP
● B. Elevating oxygen saturation with the goal of 100% saturation in all patients at risk of delayed cerebral ischemia
● C. Maintaining optimal hemoglobin with the goal of 8 to 10 Hgb
● D. Intra-arterial verapamil by endovascular interventionist to improve blood rheology and keep cerebral vascular resistance low
● E. Causing prophylactic hypervolemia

A

E. Causing prophylactic hypervolemia

243
Q

Arrythmias may occur after aneurysmal subarachnoid hemorrhage. What is the most important monitoring for this risk factor?
● A. Arterial line
● B. Airway monitoring and management with intubation
● C. Maintaining euvolemia
● D. Cardiac monitoring
● E. Intraventricular catheter

A

D. Cardiac monitoring

244
Q

What are the admitting orders for a patient with aneurysmal SAH (aSAH)?
● A. Admit in ICU with VS and neuro check every 1 hour
● B. Elevating head of bed to 30 degrees with low level of external stimulation, restricted visitation, and no loud noises
● C. Nursing care including strict I’s and O’s monitoring, daily weights, TED stocking with pneumatic compression boots and indwelling Foley catheter if lethargic
● D. Early aggressive fluid therapy to head off cerebral salt wasting which include NS + 20 mEq KCL/L at 2 mL/kg/h (140–150 mL/h)
● E. Medication, oxygenation, and temperature regulation
● F. All of the above

A

D. Early aggressive fluid therapy to head off cerebral salt wasting which include NS + 20 mEq KCL/L at 2 mL/kg/h (140–150 mL/h)

245
Q

Which of the following statements is correct regarding medication of a patient admitted in hospital after aneurysmal subarachnoid hemorrhage?
● A. Prophylactic antiseizure medications are given
● B. Analgesics are given along with dexamethasone which may help with headache and neck pain
● C. There is no role of calcium channel blockers in these patients
● D. Stool softener and antiemetics are given
● E. H2 blockers and proton pump inhibitors are given as well

A

C. There is no role of calcium channel blockers in these patients

246
Q

Risk factors for hyponatremia after SAH include diabetes, CHF, cirrhosis, adrenal insufficiency, or the use of any of the drugs like NSAIDs, acetaminophen, narcotics, and thiazide diuretics. Hyponatremic patients with SAH have incidence of delayed cerebral infarction how much times as compared to normonatremic patients?
● A. Two times
● B. Three times
● C. Four times
● D. Five times
● E. Six times

A

B. Three times

247
Q

Literature review shows that 4 to 26% of SAH patients had onset seizures, 1 to 28% had early seizures (within 2 weeks), and 1 to 35% had late seizures (after 2 weeks). Following are the risk factors for post-SAH seizure except?
● A. Increasing age (more than 65 years)
● B. MCA aneurysm or associated intracerebral or subdural hematoma
● C. Good neurologic grade
● D. Volume of subarachnoid hematoma or rebleeding
● E. Cerebral infarction or vasospasm or hyponatremia

A

C. Good neurologic grade

248
Q

About 15 to 20% of rebleed in SAH patients occur within 14 days, 50% will rebleed within 6 months; thereafter the risk is 3%/year with a mortality rate of 2%/year. The maximal frequency of rebleed is on which day after SAH (1/3 of these rebleed occur within 3 hours in that day or 1/2 within 6 hours)?
● A. 1st day
● B. 2nd day
● C. 3rd day
● D. 4th day
● E. 5th day

A

A. 1st day

249
Q

Which of the following statements is correct regarding correlation of delayed ischemic neurologic deficit (DIND) development with Hunt and Hess grade?
● A. In grade 1, there is 22% chances of DIND
● B. In grade 2, there is 33% chances of DIND
● C. In grade 3, there is 52% chances of DIND
● D. In grade 4, there is 53% chances of DIND
● E. In grade 5, there is 74% chances of DIND
● F. All of the above

A

F. All of the above

250
Q

Which of the following statements is incorrect regarding modified grading system of Fisher (correlation between the amount of blood on CT and the risk of vasospasm)?
● A. Grade 0 is no SAH or IVH
● B. Grade 1 is focal or diffuse thin SAH, no IVH with 24% symptomatic vasospasm
● C. Grade 2 is focal or diffuse thin SAH with IVH and has 33% symptomatic vasospasm
● D. Grade 3 is focal or diffuse thick SAH, with no IVH and has 33% chance of vasospasm
● E. Grade 4 is focal or diffuse thick SAH with no IVH and has 40% chance of vasospasm

A

E. Grade 4 is focal or diffuse thick SAH with no IVH and has 40% chance of vasospasm

251
Q

Which of the following is not a risk factor for re-bleeding?
● A. Male gender
● B. High-grade SAH
● C. Large aneurysm
● D. SBP > 175 mmHg
● E. Lumbar spinal drainage

A

A. Male gender

252
Q

Which method should not be used to augment cerebral oxygen delivery (DO2)?
● A. Optimizing CBF
● B. Maintaining euvolemia
● C. Nimodipine
● D. Elevate O2 saturation
● E. Induced hypertension

A

E. Induced hypertension

253
Q

A patient with aneurysmal SAH was referred for ICU care. How frequently should the neurological check be performed as a part of initial critical care?
● A. 1 hourly
● B. 2 hourly
● C. 4 hourly
● D. 6 hourly
● E. Twice daily

A

A. 1 hourly

254
Q

A patient with SAH is brought to your ICU. The family is worried about the risk of other such event. After initial hemorrhage, during which time period there is maximal risk of rebleed?
● A. Within 3 hours
● B. Within 6 hours
● C. Within 8 hours
● D. Within 12 hours
● E. Within 24 hours

A

E. Within 24 hours

255
Q

ECG of a patient with SAH show inverted T waves, prolonged QT interval, ST elevation, and U waves. The BP of the patient is 100/90. The initial management for neurogenic stress cardiomyopathy in this case includes which of the following?
● A. Dopamine
● B. Dobutamine
● C. Norpine
● D. Milrinone
● E. Potassium

A

D. Milrinone

256
Q

The management of neurogenic pulmonary edema includes furosemide supplementation along with which of the following?
● A. Alpha blockers
● B. Beta blockers
● C. Ganglion blockers
● D. Dobutamine
● E. Atracurim

A

D. Dobutamine

257
Q

A patient was referred for management of aneurysmal SAH. GCS was 13/15. After a few days the patient deteriorated to GCS 9/15 with left hemiparesis. The clinical vasospasm almost
never occurs before which day?
● A. Day 3 post SAH
● B. Day 4 post SAH
● C. Day 5 post SAH
● D. Day 7 post SAH
● E. Day 10 post SAH

A

A. Day 3 post SAH

258
Q

The family of a patient with SAH, admitted in a different hospital, brings the case summary and radiology of the patient to you to discuss referral to your setup and discuss the prognosis. You review the case summary and brain CT of the patient.
What is the percentage of symptomatic vasospasm with Fisher grade 2?
● A. 12%
● B. 24%
● C. 33%
● D. 40%
● E. 44%

A

C. 33%

259
Q

A patient with SAH is admitted in your ICU. He deteriorated on the 7th postictal day. You order a fresh CT of brain and a transcranial Doppler ultrasound. For severe vasospasm, what is the Lindegaard ratio?
● A. 2
● B. 3 to 5
● C. 4
● D. < 6
● E. > 6

A

E. > 6

260
Q

An alert patient was admitted in ICU with aneurysmal SAH. On the 7th day, he developed abulia, drowsiness, confusion, and whispering. The deterioration was attributed to clinical vasospasm. The cluster of these findings is associated with which artery?
● A. Anterior cerebral artery
● B. Middle cerebral artery
● C. Posterior cerebral artery
● D. Posterior inferior cerebellar artery
● E. Anterior inferior cerebellar artery

A

A. Anterior cerebral artery

261
Q

A patient after clipping of aneurysm is shifted under your care in ICU. How frequently would you get the renal profile as long as the patient is in ICU?
● A. Once daily
● B. Twice daily
● C. On alternate days
● D. Every 3rd day
● E. Only at time of admission to ICU

A

B. Twice daily

262
Q

During round, the consultant ordered to provide triple H therapy/hyperdynamic augmentation to a patient with aneurysmal SAH. What is the initial dose of dopamine to augment blood pressure?
● A. Start at 2.5 μg/kg/min and titrate to 15/20 μg/kg/min
● B. Start at 1 μg/kg/min and titrate to 10 μg/kg/min
● C. Start at 0.5 μg/kg/min and titrate to 10 μg/kg/min
● D. Start at 0.25 μg/kg/min and titrate to 5 μg/kg/min
● E. IV bolus of 10 μg/kg and then maintain at 10 μg/kg/min

A

A. Start at 2.5 μg/kg/min and titrate to 15/20 μg/kg/min

263
Q

Aneurysms tend to arise in areas where there is a curve in the parent artery, in the angle between it and a significant branching artery, and point in the direction where the parent artery would have continued had the curve not been present. Also, there is less elastic fiber in the tunica media and adventitia of cerebral blood vessels, the media has less muscle, the adventitia is thinner, and the internal elastic lamina is more prominent. Following are the possible etiologies of aneurysms formation except?
● A. Congenital predisposition
● B. Atherosclerotic changes or hypertension
● C. Embolic
● D. Infectious which are also called as mycotic aneurysms
● E. Trauma is never a cause of aneurysm development

A

E. Trauma is never a cause of aneurysm development

264
Q

Saccular aneurysms most commonly occur in the carotid system which accounts for about 85 to 90% of aneurysms, while posterior circulation accounts for 5 to 15% of aneurysms. What is the single most common location of aneurysm (which constitutes 30% of aneurysms)?
● A. AComA
● B. pComA
● C. Middle cerebral artery
● D. Basilar artery
● E. Vertebral artery

A

A. AComA

265
Q

Intraventricular hemorrhage occurs in 13 to 28% of cases of ruptured aneurysms in clinical series. Which of the following statements is incorrect regarding intraventricular hemorrhage and aneurysm location?
● A. Distal PICA aneurysm may rupture directly into the 4th ventricle through the foramen of Luschka
● B. AComA cause IVH by rupturing through the lamina terminalis into the anterior 3rd ventricle or lateral ventricles
● C. Distal basilar artery may rupture through the floor of the 3rd ventricle
● D. Middle cerebral artery aneurysm may rupture through the temporal horn of ventricle
● E. Carotid terminus artery aneurysm may rupture through the floor of the 3rd ventricle

A

D. Middle cerebral artery aneurysm may rupture through the temporal horn of ventricle

266
Q

Oculomotor 3rd nerve palsy occurs mostly in which aneurysm which can result in extraocular muscle palsy, ptosis, and dilated unreactive pupil?
● A. Basilar apex aneurysm
● B. PComA aneurysms
● C. PICA aneurysms
● D. AICA aneurysms
● E. None of the above

A

B. PComA aneurysms

267
Q

Which of the following are the endovascular techniques to treat aneurysm?
● A. Thrombosing the aneurysm using coiling with Guglielmi electrolytically detachable coils
● B. Thrombosing the aneurysm using Onyx 500 for wide neck or giant ICA aneurysms
● C. Using flow diversion with covered stents
● D. Trapping which can be done by distal and proximal arterial interruption using endovascular techniques
● E. All of the above

A

E. All of the above

268
Q

What is the surgical gold standard for aneurysm treatment?
● A. Coiling through endovascular technique
● B. Clipping the aneurysm
● C. Wrapping or coating the aneurysm using muscle or cotton or muslin
● D. Coating the aneurysm using Teflon or fibrin glue
● E. None of the above

A

B. Clipping the aneurysm

269
Q

Microsurgical clipping is favorable in patients with intraparenchymal hematomas, favorable dome–neck ratio, younger age, and middle cerebral artery aneurysm. Endovascular coiling may receive increased consideration in which of the following cases?
● A. Elderly patients with age more than 70 years
● B. Those with poor grade WFNS classification
● C. Those with aneurysms of basilar apex
● D. In patients with ruptured aneurysms judged to be technically amenable to both endovascular coiling and neurosurgical clipping, endovascular coiling should be considered
● E. All of the above

A

E. All of the above

270
Q

Early surgery after rupture of aneurysm is advocated because it eliminates the risk of rebleeding (which occurs mostly in period immediately post SAH), it facilitates treatment of vasospasm, and it allows lavage to remove potentially vasospasmogenic agent from contact with vessels, including use of thrombolytic agents. Which of the following are the arguments against early surgery in favor of late surgery?
● A. Inflammation and brain edema are most severe immediately post SAH which can damage brain tissue during manipulation
● B. Large clot with mass effect associated with SAH
● C. The presence of solid clot that has not had time to lyse impedes surgery
● D. The risk of intraoperative rupture is higher with early surgery
● E. Incidence of vasospasm possibly increase after early surgery from mechanotrauma to vessels

A

B. Large clot with mass effect associated with SAH

271
Q

Which of the following are the techniques that can be adopted using surgical exposure for aneurysm surgery?
● A. Brain relaxation using hyperventilation, CSF drainage (done only after opening the dura), and diuretics
● B. Cerebral protection by increasing the ischemic tolerance of the CNS using calcium channel blockers, free radical scavengers, and mannitol
● C. Reducing cerebral rate of oxygen consumption by using barbiturates, isoflurane, and prophylactic hypothermia
● D. Using adjunctive cerebral protection techniques using systemic hypotension or focal hypotension by using temporary clips
● E. All of the above

A

E. All of the above

272
Q

Which of the following statements is correct regarding the use of temporary clips using aneurysm surgery?
● A. If a long segment of the ICA is being trapped, administer 5,000 unit IV heparin to prevent thrombosis and subsequent emboli
● B. If temporary clip is applied for less than 5 minutes, then there is no need of further intervention
● C. If temporary clip is applied for 10 to 15 minutes, then administration of IV brain protection anesthesia has been shown to significantly decrease infarction rate with intermittent reperfusion
● D. More than 20 minutes of temporary clip is not tolerated
● E. All of the above

A

E. All of the above

273
Q

Which is the single most common location of cerebral aneurysms?
● A. Acomm
● B. ACA
● C. MCA
● D. Pcomm
● E. VA-PICA junction

A

A. Acomm

274
Q

What is the incidence of spontaneous thrombosis of an aneurysm?
● A. 3 to 6%
● B. 6 to 9%
● C. 9 to 13%
● D. 15 to 18%
● E. 19 to 21%

A

C. 9 to 13%

275
Q

A 50-year-old hypertensive patient was referred from DHQ for further management of SAH. Plain CT of brain shows blood predominantly in prepontine and peduncular cisterns and the third ventricle. This suggests aneurysm location as which of the following?
● A. Anterior communicating artery
● B. Anterior cerebral artery
● C. Posterior communicating artery
● D. Middle cerebral srtery
● E. Basilar apex

A

E. Basilar apex

276
Q

A middle-aged smoker presented with sudden-onset severe headache followed by seizures and loss of consciousness. Which of the following aneurysm by location is most commonly associated with seizures?
● A. Anterior communicating artery
● B. Posterior communicating artery
● C. Posterior inferior cerebellar artery
● D. Middle cerebral artery
● E. Anterior cerebral artery

A

D. Middle cerebral artery

277
Q

Facial pain syndromes in the ophthalmic or maxillary nerve distribution that may mimic trigeminal neuralgia can occur with aneurysm in which of the following?
● A. Intracavernous ICA
● B. ACA
● C. AComm
● D. Anterior choroidal artery
● E. pcomm

A

A. Intracavernous ICA

278
Q

Third cranial nerve palsy may be due to aneurysm as well as diabetes. What is an important clinical sign to help differentiate between the two causes?
● A. Pupil dilated in aneurysm
● B. Pupil dilated in diabetes
● C. No effect on pupillary reaction
● D. Ophthalmoplegia
● E. Monocular neuritis

A

A. Pupil dilated in aneurysm

279
Q

What is the screening protocol for a patient suffering from adult polycystic kidney disease (APKD) with prior aneurysm?
● A. Plain CT of brain every 2 years
● B. CTA annually
● C. CTA every 2 to 3 years
● D. MRA every 2 to 3 years
● E. MRV every 2 to 3 years

A

D. MRA every 2 to 3 years

280
Q

Treatment options for aneurysms may include all of the following except?
● A. Coiling
● B. Clipping
● C. Wrapping
● D. Antifibrinolytic therapy (e.g., ε-aminocaproic acid [EACA])
● E. Proximal ligation

A

D. Antifibrinolytic therapy (e.g., ε-aminocaproic acid [EACA])

281
Q

A patient with subarachnoid hemorrhage was referred for expert management. After initial resuscitation and basic workup, angiography studies were performed. Which of the following factors favor endovascular coiling over surgical clipping?
● A. Size < 15 mm
● B. Neck diameter < 5 mm
● C. Dome:neck ratio > 2
● D. A, B, and C
● E. Dome:neck ratio < 1.5

A

D. A, B, and C

282
Q

Regarding basilar apex aneurysm, what is the generally accepted best management option?
● A. Clipping
● B. Coiling
● C. Wrap
● D. Beta blockers
● E. Venodilaters

A

B. Coiling

283
Q

Factors that favor choosing early surgery include which of the following?
● A. Good medical condition of the patient
● B. Bad neurologic condition of the patient (H&H grade ≥ 3)
● C. Large amounts of subarachnoid blood
● D. Large clot with mass effect associated with SAH
● E. Early rebleeding, especially multiple rebleeds

A

B. Bad neurologic condition of the patient (H&H grade ≥ 3)

284
Q

A patient underwent clipping for left ACA aneurysm. Which of the followings is true regarding aneurysmal rest?
● A. Follow-up with serial angiography
● B. Can never expand
● C. If it expands, no need to re-explore
● D. No chance of re-bleed
● E. 10% incidence of re-bleed

A

A. Follow-up with serial angiography

285
Q

All of the following can be utilized for cerebral protection during aneurysm surgery except?
● A. Barbiturates
● B. Hypothermia to 34 C
● C. Intravenous mannitol
● D. Temporary clipping for 30 minutes
● E. Systemic hypotension

A

D. Temporary clipping for 30 minutes

286
Q

What is the maximum duration to safely apply a temporary clip?
● A. < 20 minutes
● B. 20 to 25 minutes
● C. 20 to 30 minutes
● D. 25 to 30 minutes
● E. 30 minutes

A

A. < 20 minutes

287
Q

Out of the three general stages of aneurysm surgery, intraoperative rupture is most likely to occur during which stage?
● A. Stage I
● B. Stage Ia
● C. Stage II
● D. Stage III
● E. Stage IV

A

C. Stage II

288
Q

A patient came into the OPD on the 17th postoperative day of clipping of right MCA aneurysm. What advice will you give regarding the next follow-up visit if the patient remains stable?
● A. CTA at 1 month
● B. CTA at 6 months
● C. CTA at 12 months
● D. CTA at 5 years
● E. CTA at 10 years

A

C. CTA at 12 months

289
Q

Following statements are correct regarding rupture of anterior communicating artery aneurysm except?
● A. It is associated with intracerebral hematoma in 63% of cases
● B. Intraventricular hematoma is seen in 79% of cases with blood entering the ventricles from the intracerebral hematoma in about one-third of these cases
● C. Acute hydrocephalus is present in 25% of cases
● D. Frontal lobe infarction never occurs after SAH from ruptured AComA
● E. These aneurysms result in blood in the interhemispheric fissure

A

D. Frontal lobe infarction never occurs after SAH from ruptured AComA

290
Q

Surgical approaches for AComA include pterional approach, subfrontal approach, anterior interhemispheric approach, and transcallosal approach. A right pterional craniotomy is used in
all the surgical procedures for AComA except in the following case?
● A. Large AcomA aneurysm pointing to right, in this case left craniotomy, exposes neck before dome
● B. Dominant left A1 feeder to aneurysm (with no filling from right A1), left craniotomy provides proximal control in this case
● C. Additional left-sided aneurysm
● D. Left-sided hematoma causing mass effect
● E. All of the above

A

E. All of the above

291
Q

Gyrus rectus resection can be done for exposure of arteries and along with it frontal temporal orbital zygoma removal, splitting of sylvian fissure, and ventricular drainage can also be done. Which of the following are critical branches to preserve during AComA aneurysm surgery?
● A. Recurrent artery of Heubner
● B. Small anterior communicating artery perforators
● C. Frontal polar branches
● D. Anterior temporal branches
● E. Both A and B

A
292
Q

Anterior of the distal anterior cerebral artery (DACA) is usually located at the origin of the frontopolar artery, or at the bifurcation of the pericallosal and callosomarginal arteries at the genu of corpus callosum. Which of the following are usually
aneurysms located more distally?
● A. Post-traumatic
● B. Infectious
● C. Mycotic
● D. Tumor embolus
● E. All of the above

A
293
Q

Aneurysms up to 1 cm from ACoA artery may be approached through a standard pterional craniotomy with partial gyrus rectus resection while aneurysms more than 1 cm distal to the anterior communicating artery are approached through which of the following?
● A. Subtemporal craniotomy
● B. Frontal craniotomy using bicoronal skin incision
● C. Orbitotemporal zygomatic approach
● D. Quadrangular flap over Keen’s point
● E. None of the above

A
294
Q

Basilar artery aneurysm constitutes only 5% of aneurysms and dome of these aneurysms usually points superiorly. Critical angiographic features to assess for basilar artery aneurysms include which of the following?
● A. Orientation of the aneurysm which is important because posteriorly pointing aneurysm obscure perforators which may be adherent to the aneurysm, making surgery more difficult
● B. Patency of PCAs and SCAs
● C. Patency and size of PComAs to determine if the P1’s can be sacrificed because diameter of more than 1 mm is needed to support the collateral flow
● D. Height of the aneurysm relative to the posterior clinoid process which will affect the selection of the surgical approach
● E. All of the above

A
295
Q

Basilar tip aneurysm can be approached through subtemporal or pterional approach. Which of the following statements are correct for comparing subtemporal and pterional approaches?
● A. Subtemporal approach provides less distance to the basilar tip as compared to pterional approach
● B. Subtemporal approach is better than pterional approach for aneurysms projecting posteriorly or posteroinferiorly
● C. Pterional approach needs little or no retraction of temporal lobe as compared to subtemporal approach in which temporal lobe needs to be retracted
● D. There is better visualization of both P1 segments and thalamoperforators using pterional approach as compared to subtemporal approach
● E. All of the above

A
296
Q

The carotid artery exits the cavernous sinus and enters the subarachnoid space at the dural constrictions known as the carotid ring (also known as clinoidal ring). The supraclinoid portion of the carotid artery is divided into the following seg-
ments except?
● A. Ophthalmic segment which gives rise to ophthalmic artery
● B. Ophthalmic segment which gives superior hypophyseal artery
● C. Communicating segment from the posterior communicating artery origin to the origin of the anterior choroidal artery
● D. Chiasmal segment which gives a branch to optic chiasma
● E. Choroidal segment from the origin of anterior choroidal artery to the terminal bifurcation of the internal carotid artery

A
297
Q

What is the correct statement regarding ophthalmic arteryaneurysm?
● A. 45% present as subarachnoid hemorrhage
● B. 45% present as visual field defect
● C. Visual field defect can be ipsilateral monocular superior nasal quadrantanopsia or monocular inferior nasal quadrantanopsia or complete loss of vision in one eye with a superior temporal quadrant defect in the contralateral eye
● D. All of the above

A
298
Q

What percentage of cerebral aneurysms consist of PICA aneurysms?
● A. 2%
● B. 3%
● C. 4%
● D. 5%
● E. 6%

A
299
Q

A patient was found unconscious by his family and was brought to emergency department. After initial resuscitation basic workup and CT of brain were advised. CT scan shows SAH with interhemispheric subdural hematoma. Which is the most likely vessel involved?
● A. Distal anterior cerebral artery
● B. Posterior communicating artery
● C. Posterior inferior cerebellar artery
● D. Anterior inferior cerebellar artery
● E. Vertebral artery

A
300
Q

A 46-year-old male presented to ER with severe headache, photophobia, and vomiting. CT of brain shows interhemispheric SAH with IVH. What is the chance for acute hydrocephalus in this patient?
● A. 79%
● B. 63%
● C. 25%
● D. 50%
● E. 100%

A
301
Q

CT angiogram of a patient with interhemispheric SAH with IVH shows large anterior communicating artery aneurysm greater than 2.5 cm, pointing superiorly along with ICH. What is the preferred surgical approach in this case?
● A. Interhemispheric approach
● B. Pterional craniotomy
● C. Subfrontal
● D. Transcolossal
● E. Subtemporal

A
302
Q

If clipping is planned, right pterional approach is usually preferred. Left pterional approach is preferred in the following except?
● A. Aneurysm pointing to left
● B. Dominant left anterior feeder
● C. Left-sided ICH
● D. Left-sided another aneurysm
● E. Left occipital horn IVH

A
303
Q

Regarding distal anterior cerebral artery (DACA) aneurysm, which of the following statements is false?
● A. Usually located at the origin of fronto-polar artery
● B. Can be post-traumatic, infective, or due to tumor emboli
● C. Aneurysms of up to 1 cm from the ACoA may be approached through pterional craniotomy
● D. Incidence of rupture is very less
● E. Both B and C options

A
304
Q

A 55-year-old male presented to ER with the worst headache of his life while he was on his way to his office. On examination, he was alert, awake, and oriented with left dilated on reactive pupil with restricted upward, inward, and outward gaze.
CT shows aneurysm which impinges on the third cranial nerve. Which of the following is a false statement?
● A. Posterior communicating artery aneurysm occurs commonly with junction to carotid artery
● B. In the presence of fetal circulation, we can sacrifice Pcomm artery without deleterious effects
● C. Pcomm aneurysm points lateral, posterior, and inferior
● D. Surgical clipping may be more advantageous than endovascular coiling to treat oculomotor nerve palsies
● E. None of the above

A
305
Q

MCA aneurysm was incidentally found on CT of brain of a 35-year-old patient. Clipping of aneurysm was planned. Which is the best statement?
● A. Superior temporal gyrus approach has a minimum brain traction and a better proximal control with decreased risk of seizures
● B. Transsylvian approach is not preferred
● C. Temporary clipping is unavoidable in case of rupture
● D. Distal MCA and recurrent perforators from the origin of the major MCA branches are critical branches to be preserved during clipping
● F. None of the above

A

D. Distal MCA and recurrent perforators from the origin of the major MCA branches are critical branches to be preserved during clipping

306
Q

Visual field defects in ophthalmic artery aneurysm is about 45% of cases. The most common patterns of field defects may include all except?
● A. Contralateral monocular superior nasal quadrantonopsia
● B. Ipsilateral monocular inferior nasal quadrantonopsia
● C. Ipsilateral blindness with contralateral junctional scotoma
● D. Ipsilateral monocular superior nasal quadrantonopsia

A

A. Contralateral monocular superior nasal quadrantonopsia

307
Q

What is the most common location of posterior circulation aneurysm?
● A. Vertebral artery aneurysm
● B. Posterior inferior cerebellar artery
● C. Vertebrobasilar junction
● D. Basilar tip
● E. Posterior communicating artery aneurysm

A

D. Basilar tip

308
Q

In posterior circulation aneurysm, vertebral artery aneurysms are more commonly associated with which of the following?
● A. Nontraumatic is more common
● B. Dissecting aneurysm is more common
● C. May not arise with VA-PICA junction
● D. Coiling is preferred option
● E. None of the above

A

D. Coiling is preferred option

309
Q

In basilar bifurcation aneurysm, height of aneurysm relative to posterior clinoid affects the selection of approach. Which is the best statement?
● A. In aneurysm greater than 5 mm, inferior approach through supraclinoid approach
● B. 5-mm aneurysm with clinoidal approach
● C. In > 5 mm aneurysm, superior approach through infraclinoidal approach
● D. Transcolossal approach for all sizes
● E. All of the above statements are correct

A

B. 5-mm aneurysm with clinoidal approach

310
Q

Which of the following are the factors that have been identified as risk for rupture of unruptured aneurysms?
● A. History of previous aneurysmal subarachnoid hemorrhage from a separate aneurysm and multiple aneurysms
● B. Medical conditions like smoking, hypertension, geographic location (North America/Europe < Japan < Finland)
● C. Annual risk of rupture of aneurysms less than 10 mm is estimated to be 0.05%/year by ISUIA study
● D. Larger aneurysms (10–25 mm) are estimated to have 3 to 18%/year risk of rupture
● E. Giant aneurysms have a risk of rupture of around 8 to 50%/ year
● F. All of the above statements are correct

A

F. All of the above statements are correct

311
Q

Following are the components of PHASES aneurysm rupture risk score except?
● A. Population
● B. Hypertension
● C. Smoking
● D. Age
● E. Size
● F. Earlier rupture from another aneurysm
● G. Site of aneurysm

A

C. Smoking

312
Q

Following are recommended management strategies for patients with unruptured aneurysms except?
● A. Large and symptomatic aneurysms (especially in younger patients) should be dealt with intervention
● B. Patients with age below 60 years and size of aneurysm less than 7 mm should undergo conservative management if it is anterior circulation aneurysm with no risk factors while if the same size aneurysm in the same patient is found in posterior circulation/PComA with symptoms present and strong family history then intervention should be done for this patient
● C. In a patient less than 60 years of age and aneurysm size more than 7 mm, intervention should be done (surgery or endovascular based on size and location)
● D. Patients more than 60 years of age with aneurysm size less than 7 mm with no family history and no risk factors should be dealt conservatively with medicines
● E. Patients more than 60 years old with aneurysm more 7 to 12 mm in size should be dealt with conservative management if in the anterior circulation or intervention should be done if aneurysm with same size is found in posterior circulation
● F. In patients with aneurysm size more than 12 mm, intervention should never be done regardless of the age or location of aneurysm

A

F. In patients with aneurysm size more than 12 mm, intervention should never be done regardless of the age or location of aneurysm

313
Q

Traumatic aneurysms may present with delayed intracranial hemorrhage, recurrent epistaxis, progressive cranial nerve palsy, enlarging skull fracture, or severe headache. What is the common location of traumatic aneurysms that arise due to
closed head injury?
● A. A1 portion of anterior cerebral artery
● B. Anterior communicating artery
● C. Distal anterior cerebral artery
● D. Middle cerebral artery
● E. Basilar artery

A

C. Distal anterior cerebral artery

314
Q

Mycotic aneurysms are infectious aneurysms that arise due to bacterial infection. These constitute 4% of intracranial aneurysms and have most common location at distal branches of middle cerebral artery. What is the most common pathogen implicated in the pathogenesis of mycotic aneurysms?
● A. Streptococcus
● B. Staphylococcus
● C. Miscellaneous
● D. Brucella species
● E. All of the above

A

A. Streptococcus

315
Q

Giant aneurysms are large aneurysms with size of more than 2.5 cm. These are of two types; the first one is saccular aneurysm while the other is fusiform aneurysm. Which of the following are included in the treatment options for these aneurysms?
● A. Direct surgical clipping
● B. Vascular bypass of aneurysm with subsequent clipping
● C. Trapping of aneurysm
● D. Proximal arterial ligation (Hunterian ligation)
● E. Endovascular treatment
● F. All of the above

A

F. All of the above

316
Q

Aneurysm that fails to be demonstrated on initial angiogram have the following causes except?
● A. Incomplete angiography
● B. Obliteration of aneurysm by the hemorrhage
● C. Thrombosis of aneurysm after SAH
● D. Good filling of aneurysm due to vasodilatation
● E. Aneurysms too small to be visualized

A

D. Good filling of aneurysm due to vasodilatation

317
Q

Which of the following are the CT or MRI criteria for diagnosis of pretruncal nonaneurysmal subarachnoid hemorrhage?
● A. Epicenter of bleeding located immediately anterior to and in contact with the brainstem
● B. Blood limited to the prepontine, interpeduncular cisterns, supracellar, interpeduncular, suprasellar, crural, ambient, and/or quadrigeminal cistern
● C. No extension of blood into the sylvian fissure or interhemispheric fissure
● D. Intraventricular blood limited to the filling of the 4th ventricle
● E. All of the above are correct

A

E. All of the above are correct

318
Q

When should repeat angiography be done in case of subarachnoid hemorrhage of unknown etiology in which there is no aneurysm found on first angiography?
● A. On the 7th day
● B. After 3 days of first angiography
● C. After 10 to 14 days of first angiography
● D. After 18 days
● E. Repeat angiography is never done in such case

A

C. After 10 to 14 days of first angiography

319
Q

When a patient presents with subarachnoid hemorrhage, then following may be the clues to find out which aneurysmhas bled except?
● A. Epicenter (area of greatest concentration) of blood on CT or MRI
● B. Area of focal vasospasm has no role in determining the site of bleed
● C. Irregularities in the shape of aneurysm (so-called Murphy’s teat)
● D. If no clue is being found, then the largest aneurysm is suspected to have bled
● E. None of the above

A

B. Area of focal vasospasm has no role in determining the site of bleed

320
Q

Arteriovenous malformations (AVMs) are dilated arteries and veins with dysplastic vessels in which arterial blood flows directly into veins without any capillary bed and no intervening neural parenchyma. Which of the following statements are
correct regarding AVM?
● A. Risk of first-time hemorrhage is 1%/year
● B. Risk of recurrent ICH is 5%/year
● C. 5-year risk of first seizure is 8% for unruptured AVM
● D. 5-year risk of epilepsy after a first seizure is 58%
● E. All of the above

A

E. All of the above

321
Q

What is the most common presentation of AVM which is about 58%?
● A. Hemorrhage
● B. Seizures
● C. Mass effect
● D. Ischemia
● E. Increased ICP

A

A. Hemorrhage

322
Q

About 7% of patients with AVM have aneurysms. These aneurysms are classified into five types. Following statements regarding classification of these aneurysms are true except?
● A. Type 1 aneurysm is proximal on ipsilateral major artery feeding AVM
● B. Type 1A is aneurysm on proximal major artery related but contralateral to AVM
● C. Type 2 is aneurysm on distal superficial feeding artery
● D. Type 4 is aneurysm on artery related to AVM
● E. Type 3 is aneurysm on proximal or distal deep feeding artery

A

D. Type 4 is aneurysm on artery related to AVM

323
Q

Characteristics of AVM on MRI include flow void on T1WI or T2WI within the AVM, feeding arteries, draining veins, and increased intensity on partial flip angle. What are the characteristics of AVM on angiography?
● A. Tangle of vessels
● B. Large feeding artery
● C. Large draining veins
● D. Draining veins are visualized in the same image as arteries
● E. All of the above

A

E. All of the above

324
Q

Following statements are correct regarding Spetzler Martin AVM grading system except?
● A. Size of AVM less than 3 cm, 3 to 6 cm, and more than 6 cm are given 1, 2, and 3 scores, respectively
● B. Score 1 is given if AVM is on eloquent brain area and score 0 is given if it is on noneloquent area
● C. If pattern of venous drainage is deep then score is 1 and if it is superficial then score is 0
● D. Class A (S-M grades 1 and 2) is treated without surgery
● E. Class C (S-M grades 4 and 5) is treated without surgery

A

D. Class A (S-M grades 1 and 2) is treated without surgery

325
Q

Which of the following statements is correct regarding pros and cons of surgery and radiation treatment for AVM?
● A. Surgery eliminates the risk of bleeding almost immediately while therapeutic response of stereotactic radiosurgery takes about 1 to 3 years during which time period risk of bleeding is about the same as natural history
● B. Surgery is an invasive procedure with high cost while stereotactic radiosurgery is a noninvasive procedure which is done on outpatient basis
● C. Seizure control improves in both surgery and radiotherapy but in the latter group it is subjected to reduction or obliteration of nidus
● D. Radiosurgery is limited to lesions less than or equal to 3 cm in size with obliteration rate of 70 to 80% and delayed side effects including radiation necrosis, brain edema, and cyst formation
● E. All of the above

A

E. All of the above

326
Q

Following are the basic tenets of AVM surgery except?
● A. Exposure should be wide
● B. Feeding arteries are isolated and occluded before draining veins
● C. Excision of whole nidus is necessary to protect against rebleeding
● D. En passant vessels and adjacent arteries are identified and preserved
● E. Dissection is done directly on nidus of AVM while working in sulci and gyri whenever possible without damaging brain parenchyma
● F. In lesions that are low flow on angiography, preoperative embolization is considered

A

F. In lesions that are low flow on angiography, preoperative embolization is considered

327
Q

For resected AVMs, follow-up is done with intraoperative or early postoperative angiogram to confirm complete removal of nidus, and residual nidus if present should be re-resected. If nidus is completely removed, then repeat catheter angiogram should be done at 1 and 5 years. Following radiosurgery, MRI/ MRA should be done at 6 months interval and if SRS-induced obliteration is demonstrated, then catheter angiogram should be done to confirm. What are the causes of delayed postoperative deterioration in case of AVM?
● A. Normal perfusion pressure breakthrough phenomenon, which is characterized by postoperative swelling or hemorrhage and it is thought to be due to loss of autoregulation
● B. Occlusive hyperemia: in the immediate postoperative period it is due to obstruction of normal venous outflow from the adjacent normal brain, while in a delayed presentation, it is due to delayed thrombosis of draining veins or dural sinus
● C. Rebleeding from a retained nidus of AVM
● D. Seizures
● E. All of the above

A

E. All of the above

328
Q

Dural arteriovenous fistula is a vascular abnormality in which an arteriovenous shunt is contained within the leaflets of the dura mater, exclusively supplied by branches of the internal/external carotid or vertebral arteries. It presents with pulsatile tinnitus, occipital bruit, headache, and visual impairment with papilledema. Which of the following statements is incorrect regarding Cognard angiographic classification of dural AVMs?
● A. Type 1 is normal anterograde flow into the dural venous sinus and it is benign
● B. Type 2a is drainage into a sinus with retrograde flow within the sinus, 2b is drainage into a sinus with retrograde flow into cortical veins, and type 2a + b is drainage into a sinus with retrograde flow within the sinus and cortical veins
● C. Type 3 is direct drainage into a cortical vein without venous ectasia
● D. Type 4 is direct drainage into a cortical vein with venous ectasia
● E. Type 5 is direct drainage into spinal perimedullary veins in exclusion of all of the above

A

E. Type 5 is direct drainage into spinal perimedullary veins in exclusion of all of the above

329
Q

Carotid cavernous fistula (CCF) is presented with orbital/retro-orbital pain, chemosis, pulsatile proptosis, ocular or cranial bruit, deterioration of visual acuity, diplopia, or pupillary dilatation. Which of the following is the type of CCF which is direct
high flow shunts between the internal carotid artery and cavernous sinus?
● A. Type A
● B. Type B
● C. Type C
● D. Type D
● E. All of the above

A

A. Type A

330
Q

Angiographically occult (cryptic) vascular malformations refer to cerebrovascular malformations that are not demonstrable on technically satisfactory catheter angiography. Which of the following are the etiologies of such condition?
● A. Lesions that have hemorrhaged in which bleeding may obliterate the lesion or the clot may temporarily compress the lesion
● B. Sluggish flow of blood within abnormal vessels
● C. Small size of the abnormal vessels
● D. May require very late angiographic films (i.e., delayed films) to visualize due to late filling
● E. All of the above

A

E. All of the above

331
Q

Angiographically occult vascular malformation most commonly present with which of the following?
● A. Seizures or headache
● B. Progressive neurologic symptoms
● C. One-sided body weakness
● D. Memory deficit
● E. Urinary incontinence

A

A. Seizures or headache

332
Q

Osler Weber Rendu syndrome, also known as hereditary hemorrhagic telangiectasia or capillary telangiectasia, is slightly enlarged capillaries with low flow. It is usually incidentally found at necropsy and has very low risk of hemorrhage (except possibly in brainstem) with intervening neural tissue. Associated cerebrovascular malformations with it include the following except?
● A. AVMs
● B. Vein of Galen malformation
● C. Venous angiomas
● D. Aneurysms
● E. Telangiectasia

A

B. Vein of Galen malformation

333
Q

Osler Weber Rendu syndrome may show a well-demarcated homogenous or mottled high density with some form of contrast enhancement on CT of brain. On T2WI, there is found reticulated core of increased and decreased intensity, and a prominent surrounding rim of reduced intensity may be present. What is the most suitable treatment option for this disease?
● A. Surgery is indicated for evacuation of hematoma or for recurrent hemorrhages
● B. Stereotactic radiosurgery is the most suitable option
● C. Embolization is superior to all other modalities
● D. Treatment is only with medication
● E. There is no known treatment for this disease

A

A. Surgery is indicated for evacuation of hematoma or for recurrent hemorrhages

334
Q

Cavernous malformation is an angiographically occult lesion with low flow vessels and no intervening neural parenchyma or arteries. What is the study of choice for this lesion (on which it appears as popcorn pattern)?
● A. CT angiography of brain
● B. MRI, especially gradient echo or SWI
● C. Catheter angiogram
● D. CT with IV contrast
● E. PET scan

A

B. MRI, especially gradient echo or SWI

335
Q

Cavernoma or cavernous hemangioma or angioma or hemangioma is a well-circumscribed, benign vascular hamartoma consisting of irregular thick and thin-walled sinusoidal vascular channels located within the brain but lacking intervening neural parenchyma, large feeding arteries, or large draining
veins. Structural characteristics of this lesion include which of the following?
● A. Comprised of dilated endothelial lined capillary vessels (caverns) with defective tight junctions
● B. No identifiable arterial feeders on angiography
● C. Often associated with a developmental venous anomaly (DVA)
● D. No functional brain tissue with the encapsulated core
● E. All of the above

A

E. All of the above

336
Q

Cavernous malformation constitutes 5 to 13% of CNS vascular malformations. What is the most common location of these lesions?
● A. Brainstem
● B. Supratentorial
● C. Basal ganglia
● D. Spinal cord
● E. Cerebellum

A

B. Supratentorial

337
Q

Which of the following is incorrect regarding Zabramski classification of cavernous malformations?
● A. Type 1 is subacute hemorrhage with a rim of hemosiderinladen macrophages and gliotic brain
● B. Type 2 is loculated areas of hemorrhage and thrombus of varying age with a rim of gliotic, hemosiderin-stained brain, with large lesions that may have areas of calcifications
● C. Type 3 is chronic resolved hemorrhage with hemosiderin staining within and around the cavernous malformation
● D. Some lesions in type 4 category were found to be telangiectasia
● E. Type 5 presents with intralesional hemorrhage

A

E. Type 5 presents with intralesional hemorrhage

338
Q

Which of the following statements is incorrect regarding surgical management of cavernous malformations (CMs)?
● A. Surgery is not recommended for asymptomatic CMs, especially those that are deep or in eloquent areas or brainstem, or with multiple CMs
● B. Consider surgery for solitary asymptomatic CMs if easily accessible and not in eloquent brain, to prevent future hemorrhage, because of psychological burden, expensive timeconsuming follow-ups, to facilitate lifestyle or career decision, or in patients who might need to be on anticoagulants
● C. Early CM resection is considered (≤ 6 weeks from hemorrhage) in patients with seizures, especially when medically refractory, if the CM is the likely cause of the seizure
● D. Consider surgery in symptomatic easily accessible CMs (surgical morbidity and mortality is equivalent to living with the CM for 1–2 years after a first bleed)
● E. Consider surgery after a symptomatic second bleed in a brainstem cavernous malformation
● F. Consider radiosurgery in solitary CMs with previous symptomatic hemorrhage if the CM is located in eloquent areas that have an unacceptably high risk with surgery
● G. All of the above are correct

A

G. All of the above are correct

339
Q

Stereotactic localization or intraoperative ultrasound is particularly helpful in localizing the cavernous malformation. What is the goal of surgery in case of cavernous malformation?
● A. Only decompression
● B. Decompression with removal of hematoma
● C. Complete resection of the lesion
● D. Removing only symptomatic portion of the lesion
● E. None of the above

A

C. Complete resection of the lesion

340
Q

The reason for a vascular lesion being angiographically cryptic does not include which of the following?
● A. Lesions that have hemorrhaged
● B. The bleeding may obliterate the lesion
● C. The clot may temporarily compress the lesion
● D. Fast flow
● E. May require delayed film to visualize due to late filling

A

D. Fast flow

341
Q

Multiple lesions in hereditary hemorrhagic telangiectasia are not associated with which of the following?
● A. Osler Weber Rendu syndrome
● B. Louis-Barr
● C. Myburn Mason
● D. Sturge Weber
● E. Multiple endocrine neoplasia type I

A

E. Multiple endocrine neoplasia type I

342
Q

In hereditary hemorrhagic telangiectasia (HHT), surgery is indicated mainly for which of the following?
● A. Unruptured lesion
● B. Diagnosis
● C. Thalamic location
● D. 1st hemorrhage
● E. Well-controlled seizures

A

B. Diagnosis

343
Q

A patient is admitted with seizures and ICH. What is the typical MRI radiologic sign for cavernoma?
● A. Popcorn
● B. Spokes of wheel
● C. Sunburst
● D. Sunset
● E. Caput medusae

A

A. Popcorn

344
Q

Which of the following is a risk factor for formation of cavernous malformation?
● A. Trauma
● B. Radiotherapy
● C. Diabetes
● D. Smoking
● E. Ehlers Danlos disease

A

B. Radiotherapy

345
Q

When is a hemorrhage considered to have occurred in cavernous malformation?
● A. Only lesion growth without signal change
● B. Presence of hemosiderin without signs of a recent hemorrhage
● C. The appearance of blood-degradation products without lesion growth
● D. Edema with blood degradation products
● E. Blood products without clinical symptoms

A

D. Edema with blood degradation products

346
Q

According to Zabramski classification of cavernous malformations loculated areas of hemorrhage and thrombus of varying age with a rim of gliotic, hemosiderin-stained brain with calcifications had an annual hemorrhage rate of how much?
● A. 8.9%
● B. 12.3%
● C. 17.6%
● D. 20.1%
● E. 23.7%

A

D. 20.1%

347
Q

Early cavernous malformation (CM) resection (≤ 6 weeks from hemorrhage) should be considered in patients with which of the following?
● A. Seizures, especially when medically refractory, if the CM is the likely cause of the seizure
● B. Asymptomatic CMs
● C. Deep CM
● D. Brainstem CM
● E. Multiple CMs

A

A. Seizures, especially when medically refractory, if the CM is the likely cause of the seizure

348
Q

Following statements are correct except?
● A. Transient ischemic attack (TIA) is transient neuronal dysfunction secondary to focal ischemia of brain, spinal cord, or retina without (permanent) acute infarction (10–15% of patients with TIA have stroke within 3 months)
● B. Stroke is permanent (irreversible) death of neurons caused by hyperperfusion of a region of the brain or brainstem
● C. Watershed infarct is ischemic infarction in a territory located at the periphery of two bordering arterial distributions due to a disturbance in flow in one or both of the arteries
● D. Normal cerebral blood flow is 45 to 60 mL/100-g tissue/min
● E. Normal cerebral metabolic rate of oxygen consumption averages about 3.0 to 3.8 mL/100-g tissue/min

A

B. Stroke is permanent (irreversible) death of neurons caused by hyperperfusion of a region of the brain or brainstem

349
Q

The effects of ICA stenosis/occlusion may be ameliorated by collateral blood flow. Potential alternate routes for blood to reach brain tissue include the following except?
● A. Flow through circle of Willis from contralateral ICA through anterior communicating artery and from forward flow through the ipsilateral posterior communicating artery
● B. Retrograde flow through ophthalmic artery parasitizing blood from both ECAs via facial artery, maxillary artery, transverse facial artery, and superficial temporal artery
● C. Proximal maxillary artery
● D. Cortical–cortical anastomoses
● E. Dural–dural anastomosis

A

E. Dural–dural anastomosis

350
Q

A patient presents with expressive aphasia + mild hemiparesis (upper extremity more than lower extremity, proximal muscle weaker than distal) in neurosurgical emergency. What is the most likely blood vessel involved in this case?
● A. Anterior choroidal artery
● B. Recurrent medial striate artery (of Heubner)
● C. Posterior cerebral artery
● D. Anterior cerebral artery
● E. Anterior inferior cerebral artery

A

B. Recurrent medial striate artery (of Heubner)

351
Q

A patient presents with vertigo, nausea and vomiting, diplopia, oscillopsia, hiccups with ipsilateral facial pain, paresthesias, impaired sensation, ataxia of limbs, Horner syndrome
dysphagia, and hoarseness of voice. This patient is diagnosed with lateral medullary syndrome (also known as Wallenberg’s syndrome). What is the most likely artery occluded in this syndrome?
● A. AICA
● B. Posterior cerebral artery
● C. Anterior cerebral artery
● D. Posterior inferior cerebral artery
● E. Anterior choroidal artery

A

D. Posterior inferior cerebral artery

352
Q

Small infarcts in deep noncortical cerebrum or brainstem result from occlusion of penetrating branches of cerebral arteries. Size of infarcts ranges from 3 to 20 mm. Which of the following is the typical location for lacunar infarcts?
● A. Putamen and caudate
● B. Thalamus
● C. Pons and internal capsule
● D. Convolutional white matter
● E. All of the above

A

E. All of the above

353
Q

Trauma is the most common cause of stroke in young adults making 22% of total stroke causes in young adults. What is the second most common cause of stroke in young adults (comprising about 20% of stroke cases)?
● A. Atherosclerosis
● B. Embolisms with source from cardiac origin or fat embolism syndrome or paradoxical embolism
● C. Vasculopathy or coagulopathy
● D. Peripartum
● E. Both A and B

A

E. Both A and B

354
Q

Carotid artery lesions are considered symptomatic if there are one or more lateralizing ischemic episodes appropriate to the distribution of the lesion. What is the acceptable initial screening test for carotid artery stenosis?
● A. Catheter angiogram
● B. Doppler
● C. CTA
● D. MRA
● E. All of the above except A

A

E. All of the above except A

355
Q

What are the medical management options for carotid artery stenosis?
● A. Antiplatelet therapy including aspirin, P2Y12 receptor blockers, combination of dipyridamole and ASA
● B. Antihypertensive therapy
● C. Good control of diabetes
● D. Antilipid therapy
● E. Patients with asymptomatic atrial fibrillation should be treated with anticoagulation
● F. Intervention to help patients to quit smoking
● G. All of the above

A

G. All of the above

356
Q

Which of the following statements is incorrect regarding practice guidelines of asymptomatic carotid stenosis?
● A. Carotid endarterectomy is reasonable in asymptomatic patients with more than 70% stenosis if risk of perioperative stroke, MI, and death is low
● B. Prophylactic carotid artery stenting may be considered in highly selected patients with asymptomatic ICA stenosis (more than 60% by angiography, more than 70% by validated
Doppler ultrasound)
● C. In patients with age more than 80 years, the effectiveness of revascularization over medical therapy alone is not well recognized
● D. It is reasonable to choose carotid artery stenting over carotid endarterectomy when revascularization is not indicated in patients with anatomy favorable for surgery
● E. None of the above

A

D. It is reasonable to choose carotid artery stenting over carotid endarterectomy when revascularization is not indicated in patients with anatomy favorable for surgery

357
Q

What is the gold standard test for carotid artery stenosis?
● A. Catheter angiogram
● B. Doppler ultrasound
● C. CT angiography brain
● D. Magnetic resonance imaging
● E. All of the above

A

A. Catheter angiogram

358
Q

What is the cerebral blood flow (mL/100-g tissue/min) for normal brain at rest?
● A. 15 to 30
● B. 30 to 45
● C. 45 to 60
● D. 55 to 80
● E. > 70

A

C. 45 to 60

359
Q

What is the typical EEG change for ischemic brain?
● A. Flat line
● B. Tall alpha waves
● C. Increased amplitude
● D. Frequency > 50 Hz
● E. Bizarre pattern

A

A. Flat line

360
Q

Marie-Fox syndrome/lateral pontine syndrome is associated with the occlusion of which of the following?
● A. Posterior inferior cerebellar artery
● B. Anterior inferior cerebellar artery
● C. Anterior choroidal artery
● D. Superior cerebellar artery
● E. Inferior petrosal vein

A

B. Anterior inferior cerebellar artery

361
Q

Lacunar infarct most commonly involves which of the following locations?
● A. Putamen
● B. Thalamus
● C. Pons
● D. Internal capsule
● E. Convulational white matter

A

A. Putamen

362
Q

Pure motor hemiparesis sparing face indicates a lacune in which of the following?
● A. Medullary pyramid
● B. Posteroventral thalamus
● C. Lower basis pontis
● D. Posterior limb of internal capsule
● E. Mesencephalothalamus

A

A. Medullary pyramid

363
Q

What is the most common cause of ischemic stroke?
● A. Trauma
● B. Embolism with a recognized source
● C. Atherosclerosis
● D. Fat embolism
● E. Hypercoagulable states

A

A. Trauma

364
Q

What is the most frequently associated risk factor for ischemic stroke?
● A. Diabetes mellitus
● B. Hypertension
● C. Smoking
● D. Chronic alcoholism
● E. Obesity

A

A. Diabetes mellitus

365
Q

What is the gold standard test for internal carotid artery stenosis?
● A. CT angiography
● B. Catheter angiogram
● C. 2D TOF MRI
● D. B mode duplex ultrasound
● E. MRA

A

B. Catheter angiogram

366
Q

What is the loading dose of clopidogrel for internal carotid artery stenosis?
● A. 75 mg
● B. 150 mg
● C. 225 mg
● D. 500 mg
● E. 1500 mg

A

C. 225 mg

367
Q

According to ECST measurements for internal carotid artery stenosis, what is the degree of stenosis for which surgery does not have any clear benefit for symptomatic patients?
● A. 65
● B. 70
● C. 75
● D. 91
● E. 95

A

A. 65

368
Q

In case of acute stroke, treatment benefits are time dependent. Initial evaluation steps include history/physical examination, noncontrast brain CT, blood glucose level, and CTA in some cases. What is the optimal time of administration of tissue plasminogen activator alteplase in a patient with acute ischemic stroke?
● A. Within 3.5 hours
● B. Within 4 hours
● C. Within 4.5 hours
● D. Within 5 hours
● E. Within 6 hours

A

C. Within 4.5 hours

369
Q

Following are included in the NIH stroke scale except?
● A. Level of consciousness, level of consciousness questions, and level of consciousness commands
● B. Best gaze and visual
● C. Facial palsy, motor arm, motor leg, limb ataxia, and sensory
● D. Ophthalmoplegia and dysphagia
● E. Best language and dysarthria
● F. Extinction and inattention and distal motor function

A

D. Ophthalmoplegia and dysphagia

370
Q

Which of the following statements is incorrect regarding treatment of hypertension in a patient with acute ischemic stroke?
● A. If diastolic blood pressure is more than 140 mmHg, then 20 to 30% reduction is desirable with cardene infusion or IV labetalol is the agent of choice
● B. Systolic blood pressure more than 230 or diastolic blood pressure 120 to 140 for 20 minutes is treated with 10 mg slow IV infusion over 2 minutes of labetalol. The dosage of labetalol is doubled every 10 minutes (20, 40, 80, then 160 mg IV slow until controlled or total of 300 mg is given)
● C. Maintenance is effective dose of labetalol every 6 to 8 hours for SBP more than 180 or DBP more than 110
● D. SBP 180 to 230 or DBP more than 105 to 120 is treated with oral labetalol
● E. If labetalol is contraindicated, nicardipine is never used

A

E. If labetalol is contraindicated, nicardipine is never used

371
Q

What are the indications of emergency surgery in case of acute stroke?
● A. Herniation from subdural hematoma
● B. Suboccipital craniectomy for progressive neurologic deterioration due to brainstem compression from cerebellar hemorrhage or infarction
● C. Decompressive craniectomy for malignant MCA territory stroke
● D. Carotid endarterectomy for high-grade carotid stenosis ipsilateral to fluctuating neuro deficit
● E. All of the above

A

E. All of the above

372
Q

Which of the following are the early signs of infarction within 6 hours (hyperacute) of onset of ischemic stroke?
● A. Hyperdense artery sign
● B. Focal low attenuation within the gray matter and loss of the gray–white interface
● C. Attenuation of the lentiform nucleus or mass effect with effacement of cerebral sulci or with midline shift
● D. Lost of the insular ribbon sign which is hypodensity involving the insular cortex, susceptible to ischemia due to poor collaterals
● E. Infarction with IV contrast which occurs in only 33% of cases
● F. All of the above

A

F. All of the above

373
Q

Most strokes can be identified as low density after 24 hours. When does stroke approaches that of CSF density?
● A. At 1 to 2 weeks
● B. At 3 weeks
● C. At 6 weeks
● D. At 3 months
● E. None of the above

A

B. At 3 weeks

374
Q

Preoperative management of carotid endarterectomy includes acetylsalicylic acid 325 mg TID for at least 2 days or preferably for 5 days. Postoperative management after the procedure includes ICU monitoring with BP at 110 to 115 mmHg and avoidance of antiplatelet therapy for 24 to 48 hours postoperatively. Which of the following are the postoperative complications that can occur after the procedure?
● A. Disruption of arteriotomy closure
● B. Stroke
● C. Postoperative TIAs and seizures
● D. Cerebral hypoperfusion syndrome
● E. Cranial nerve injury

A

D. Cerebral hypoperfusion syndrome

375
Q

Indications of carotid endarterectomy includes stroke in evolution, crescendo TIAs, or following intra-arterial thrombolysis. Emergent carotid endarterectomy (CEA) is indicated for residual critical carotid stenosis. Which of the following are the possible techniques for management of thrombus?
● A. Spontaneous extrusion is attempted using back pressure
● B. If A fails then removal using smoothened suction catheter is attempted
● C. If B fails then balloon embolectomy catheter is used by passing it as far as base of the skull
● D. Intraoperative angiogram is obtained unless thrombus emerges and backflow is excellent
● E. Plicate ICA (avoid creating a blind pouch at origin) if there is good backflow or if satisfactory angiography cannot be obtained
● F. All of the above

A

F. All of the above

376
Q

What is the most sensitive test to detect ischemic stroke within 24 hours of occurrence?
● A. MRI with contrast
● B. CT with contrast
● C. DWI MRI
● D. CT angiography of brain
● E. CT perfusion

A

C. DWI MRI

377
Q

Contraindications for administration of tissue plasminogen activator includes intracerebral hemorrhage, patients with history of more than 10 cerebral microbleeds, clinical presentation of SAH, active internal bleeding, known intracranial
aneurysm, or SVM, known bleeding diathesis, serious head trauma, and systolic blood pressure more than 185 mmHg or diastolic blood pressure more than 110 mmHg. Which of the following are included in the eligibility criteria in the administration of tissue plasminogen activator?
● A. Age above 18 years
● B. Time since last seen normal less than or equal to 4.5 hours prior to administration
● C. AIS in adults with known sickle disease
● D. tPA is reasonable in otherwise eligible patients with history of less than or equal to 10 cerebral microbleeds on MRI
● E. All of the above

A

E. All of the above

378
Q

Following statements are correct except?
● A. Cerebral arterial dissection can be spontaneous, post-traumatic, or iatrogenic
● B. Dissection means extravasation of blood between the intima and media, creating luminal narrowing or occlusion
● C. Dissecting aneurysm is dissection of blood between the media and adventitia or at the media causing aneurysmal dilatation which may rupture into the subarachnoid space
● D. Pseudoaneurysm is rupture of artery with subsequent encapsulation of the extravascular hematoma, and may or may not produce luminal narrowing
● E. Cerebral arterial dissection may present with TIA or Horner syndrome but never present with pain

A

E. Cerebral arterial dissection may present with TIA or Horner syndrome but never present with pain

379
Q

The lesion common to all dissections is hemorrhage outside of the vascular lumen due to pathological transintimal extravasation of blood from the true lumen into the vessel wall. What is the most common site of spontaneous intracranial dissection?
● A. Basilar artery
● B. Vertebral artery
● C. Internal carotid artery
● D. Middle cerebral artery
● E. Anterior cerebral artery

A

B. Vertebral artery

380
Q

Cerebral arterial dissection may cause symptoms by embolization secondary to platelet aggregation, dislodged thrombus causing reduced distal flow, or subarachnoid hemorrhage. The most common presentation in patients with age less than 30
years is due to dissection of which artery?
● A. Vertebral artery
● B. Basilar artery
● C. Internal carotid artery
● D. Posterior cerebral artery
● E. Anterior cerebral artery

A

C. Internal carotid artery

381
Q

What is the definitive diagnostic study for cerebral arterial dissection?
● A. CT of brain with IV contrast
● B. CT angiogram of brain
● C. Catheter angiography of brain
● D. MRI of brain with IV contrast
● E. Plain CT of brain

A

C. Catheter angiography of brain

382
Q

What is the most common clinical feature of spontaneous internal carotid artery dissection?
● A. Focal cerebral ischemia
● B. Headache
● C. Oculosympathetic palsy
● D. Bruit
● E. Amaurosis fugax

A

A. Focal cerebral ischemia

383
Q

Traumatic dissections of vertebral artery tend to occur where it crosses bony prominences, for example, at the c1–c2 junction or where it enters the foramen transversarium usually at c6. Whereas spontaneous VA dissections are associated with fibromuscular dysplasia, migraine, and oral contraceptive pills. What is the prominent early finding in spontaneous extradural dissection of VA?
● A. TIAs or stroke
● B. Cerebellar infarction
● C. Neck pain over posterior cervical region or over occiput
● D. Lateral medullary syndrome
● E. Dysphagia

A

C. Neck pain over posterior cervical region or over occiput

384
Q

Moyamoya disease looks like “puff of cigarette smoke” due to secondary formation of an anastomotic collateral capillary network at the base of the brain. Progressive spontaneous occlusion of which arteries lead to this disease?
● A. Vertebral arteries
● B. Basilar arteries
● C. Both internal carotid arteries
● D. Posterior inferior cerebral arteries
● E. None of the above

A

C. Both internal carotid arteries

385
Q

Intracranial aneurysms are frequently associated with moyamoya disease. It may be as a result of increased flow through dilated collaterals or it may be that patients with moyamoya may also have a congenital defect in the arterial wall that predisposes them to aneurysms. What are the types of aneurysms that are associated with moyamoya disease?
● A. Aneurysms at the circle of Willis
● B. Aneurysms in the peripheral portion of cerebral arteries, for example, posterior/anterior choroidal or Heubner’s artery
● C. Within moyamoya vessels
● D. All of the above

A

D. All of the above

386
Q

What is the most common presentation of moyamoya disease?
● A. Ischemic infarcts/TIAs
● B. Hemorrhage
● C. Aneurysms
● D. Ischemic infarcts/TIAs in children and hemorrhage in adults
● E. None of the above

A

D. Ischemic infarcts/TIAs in children and hemorrhage in adults

387
Q

Medical treatment for moyamoya disease includes antiplatelet drugs, anticoagulation, or vasodilators while surgical option includes revascularization. Cerebral angiography is necessary to delineate the degree of stenosis as well as to evaluate potential extracranial donor vessels for revascularization. Which of the following is the angiographic finding in the moyamoya disease (Suzuki stages)?
● A. Stage 1 is stenosis of suprasellar ICA, usually bilateral
● B. Stage 2 is development of moyamoya vessels at the base of brain. ACA, MCA, and PCA are dilated
● C. Stage 3 is increasing ICA stenosis and prominence of moyamoya vessels (most cases diagnosed at this stage). Maximal basal moyamoya
● D. Stage 4 is entire circle of Willis and PCAs occluded, extracranial collaterals start to appear, and moyamoya vessels begin to diminish
● E. Stage 5 is further progression of stage 4 with intensification of ECA collaterals and reduction of moyamoya-associated vessels
● F. Stage 6 is occlusion of ICA and major cerebral arteries and complete absence of moyamoya vessels
● G. All of the above

A

G. All of the above

388
Q

Which of the following is the most common vessel involved in cerebral arterial dissection?
● A. Basilar artery
● B. Vertebral artery
● C. Internal carotid artery
● D. External carotid artery
● E. Common carotid artery

A

B. Vertebral artery

389
Q

The angiographic radiologic signs for cerebral arterial dissection include all of the following except?
● A. String and pearl
● B. Wavy ripple
● C. Sunburst
● D. String of beads
● E. Double lumen

A

C. Sunburst

390
Q

Which of the following is the most common site of pain in spontaneous ICA dissections?
● A. Orbital or periorbital
● B. Auricular or mastoid
● C. Frontal
● D. Temporal
● E. Over carotid artery

A

A. Orbital or periorbital

391
Q

For vertebral artery dissection, oral anticoagulation should be continued for how long?
● A. 24 hours
● B. 21 days
● C. 1 month
● D. 6 months
● E. 1 year

A

D. 6 months

392
Q

Which of the following is the most common initial symptom of spontaneous internal carotid artery dissection?
● A. Unilateral headache
● B. Seizures
● C. Altered level of conscious
● D. Facial palsy
● E. Proptosis

A

A. Unilateral headache

393
Q

In a patient with dissection involving dominant vertebral artery, who does not tolerate occlusion what is the best alternative?
● A. Clipping proximal to PICA origin
● B. Trapping the aneurysm between clips
● C. Clipping VA distal to PICA take off
● D. Huntarian ligation
● E. Side-to-side PICA–PICA anastomosis

A

E. Side-to-side PICA–PICA anastomosis

394
Q

Which of the following is a likely etiology of primary moyamoya disease?
● A. Graves’ disease
● B. Elevated basic fibroblast growth factor
● C. History of cerebral inflammatory disease
● D. Previous head trauma
● E. Radiation therapy for skull base glioma in children

A

B. Elevated basic fibroblast growth factor

395
Q

What is the radiologic sign on CT angiogram for moyamoya disease?
● A. Tangled ball
● B. Puff of smoke
● C. Chimney
● D. Coconut
● E. Sunburst

A

B. Puff of smoke

396
Q

CT angiogram shows bilateral stenosis of suprasellar ICA. What is the angiographic stage of moyamoya disease in this case?
● A. 1
● B. 2
● C. 3
● D. 4
● E. 5

A

A. 1

397
Q

Which of the angiographic stages of moyamoya disease should be considered for revascularization?
● A. 1–2
● B. 2–4
● C. 5
● D. 4–6
● E. All of the stages

A

B. 2–4

398
Q

How long after an acute ischemic attack should revascularization procedure be attempted for moyamoya disease?
● A. > 2 weeks after the most recent attack
● B. > 4 weeks
● C. > 6 weeks
● D. > 2 months
● E. > 6 months

A

D. > 2 months

399
Q

Which of the following procedures has the highest potential to revascularize ischemic tissue in moyamoya disease?
● A. Encephalomyosynangiosis
● B. Encephaloduroateriosynangiosis
● C. Omental transposition
● D. Frontal burr holes
● E. Ribbon EDAS

A

C. Omental transposition

400
Q

What are the patterns of stroke with total internal carotid artery occlusion?
● A. Whole hemispheric stroke
● B. Watershed infarct
● C. Carotid stump syndrome in which there are continued cerebral or retinal symptoms due to inadequacy of collaterals or due to emboli formed in the turbulent flow
● D. Whole brain ischemic symptoms
● E. All of them except D

A

E. All of them except D

401
Q

Intra-arterial thrombolysis within 6 hours of onset of symptoms may increase recanalization rate and clinical improvement without significant increase in hemorrhagic transformation as compared to intravenous thrombolytic therapy. Surgical
options for these cases include carotid endarterectomy. Which patient is the candidate for surgical intervention in case of total internal carotid artery occlusion?
● A. Patients with acute neuro deficit associated with total occlusion presenting after about 2 hours
● B. Patients with extremely poor neuro deficit
● C. Patients with acute neuro deficit associated with total occlusion of internal carotid artery within 2 hours of symptoms onset
● D. Patients without persistent neuro deficit with total ICA occlusion
● E. Both C and D

A

E. Both C and D

402
Q

A patient presents with symptoms of dizziness, vertigo, nausea, vomiting, loss of balance, and headache. This patient also has signs of truncal and appendicular ataxia, nystagmus, and dysarthria. This patient’s scan showed compression and obliteration of basal cisterns and 4th ventricle, hydrocephalus, and tight posterior fossa. In 1 hour, this patient develops deep coma and is found to have cerebellar infarct. What is the management option at this stage of the patient?
● A. Conservative and counselling of the attendants
● B. Surgical decompression with brain frontal lobectomy
● C. Suboccipital craniectomy
● D. Suboccipital craniectomy with enlargement of foramen magnum
● E. Only supportive therapy with ventilatory support

A

D. Suboccipital craniectomy with enlargement of foramen magnum

403
Q

A patient presents with severe drowsiness, dense hemiplegia, early parenchymal hypodensity involving more than 50% of the MCA distribution on brain CT, midline shift of more than 8 to 10 mm, and hyperdense artery sign in MCA. What are the options of management in case of malignant middle cerebral artery infarction (which carries mortality of up to 80%)?
● A. Conventional measures to control ICP
● B. A + Hemicraniectomy
● C. Agents to lyse clot
● D. Hyperventilation, mannitol, or barbiturate coma
● E. Both C and D

A

B. A + Hemicraniectomy

404
Q

Guidelines for hemicraniectomy in a patient with malignant MCA infarct include age less than 70 years, more strongly considered in nondominant hemisphere, and CT or clinical evidence of acute complete ICA or MCA infarcts with direct signs
of impending or complete severe hemispheric brain swelling. When should hemicraniectomy be performed to decrease the mortality and increase functional outcome?
● A. Within 24 hours
● B. Within 48 hours
● C. Within 6 hours
● D. Within 12 hours
● E. Within 72 hours

A

B. Within 48 hours

405
Q

Causes of cardiogenic brain embolism include acute myocardial infarction, atrial fibrillation, prosthetic heart valves, paradoxical embolism, or endocarditis. Which of the following are the components of CHADS2 scoring system for risk of stroke with atrial fibrillation?
● A. CHF
● B. HTN
● C. Smoking
● D. Age more than 75 years
● E. Diabetes mellitus

A

C. Smoking

406
Q

Following are the management steps for cardiogenic brain ischemic stroke except?
● A. CT should be obtained within 48 hours
● B. Anticoagulation should be used for large infarcts
● C. Heparin and warfarin are started simultaneously
● D. An INR of 2 to 3 appears satisfactory
● E. ASA is only about half as effective as warfarin but may be sufficient for those without associated risk factors

A

B. Anticoagulation should be used for large infarcts

407
Q

Criteria for clinical diagnosis of vertebral basilar insufficiency include any two of the following: motor or sensory symptoms or both occurring bilaterally in the same event, diplopia which is due to upper brainstem involvement, dysarthria which is
due to lower brainstem involvement, or homonymous hemianopia which is due to ischemia of occipital cortex. What are the surgical treatment options for this condition?
● A. Vertebral endarterectomy
● B. Transposition of VA to ICA
● C. Bypass grafting
● D. C1 and C2 posterior arthrodesis in case of os odontoideum
● E. All of the above

A

E. All of the above

408
Q

The most frequently involved sinus in cerebral venous thrombosis is superior sagittal sinus or left transverse sinus. Following are the signs on noncontrast that can help diagnose case of cerebral venous thrombosis except?
● A. Hyperdense sign or cortical vein of high density or clots in cortical veins
● B. Hemorrhage
● C. Small ventricles
● D. Venous infarct and white matter edema never occur with it
● E. Triangular shaped high density within the sinus posteriorly near the torcular herophili on axial CT images

A

D. Venous infarct and white matter edema never occur with it

409
Q

For EC/ICA bypass graft, the type of graft depends on preoperative determination of amount of flow augmentation necessary, the size of recipient graft, and availability of donor vessel. What type of graft is used for high flow vessel with 70 to 140 mL/min flow rate?
● A. Superficial temporal artery
● B. Saphenous vein graft
● C. Radial artery graft
● D. Occipital artery
● E. All of the above

A

B. Saphenous vein graft

410
Q

What is the overall rate of subsequent ischemic stroke ipsilateral to the occluded carotid artery?
● A. 2.9% per year
● B. 3.9% per year
● C. 4.9% per year
● D. 5.9% per year
● E. 6.9% per year

A

D. 5.9% per year

411
Q

The emergency operations for acute neurological deficit associated with total occlusion of ICA should not be performed after how long?
● A. 2 hours
● B. 3 hours
● C. 4 hours
● D. 6 hours
● E. 12 hours

A

A. 2 hours

412
Q

In case of cerebellar infarction, surgical decompression should not be attempted in presence of which of the following symptoms?
● A. Abducens (VI) nerve palsy, loss of ipsilateral gaze (compression of VI nucleus and lateral gaze center)
● B. Peripheral facial nerve paresis (compression of facial colliculus), confusion, and somnolence (may be partly due to developing hydrocephalus)
● C. Babinski sign, hemiparesis, lethargy
● D. Small but reactive pupils coma posturing→ flaccidity, ataxic respirations
● E. Dysphagia, dysarthria, Horner syndrome, ipsilateral facial numbness, crossed sensory loss

A

E. Dysphagia, dysarthria, Horner syndrome, ipsilateral facial numbness, crossed sensory loss

413
Q

For malignant MCA infarct, mortality is reduced if hemicraniectomy is performed within what time?
● A. 48 hours
● B. 96 hours
● C. 3 days
● D. 5 days
● E. 7 days

A

A. 48 hours

414
Q

Paradoxical cardiogenic embolism can occur with which of the following?
● A. Left ventricular hypertrophy
● B. Patent foramen ovale
● C. Subacute bacterial endocarditis
● D. Moyamoya disease
● E. Prosthetic heart valves

A

B. Patent foramen ovale

415
Q

Which of the following is not a component of CHAD2 scoring system?
● A. Congestive cardiac failure
● B. Hypertension
● C. Age
● D. Diabetes
● E. Hypercholesterolemia

A

E. Hypercholesterolemia

416
Q

Criteria for clinical diagnosis of vertebrobasilar insufficiency include all of the following except?
● A. Diplopia
● B. Dysarthria
● C. Homonymous hemianopsia
● D. Repetitive speech
● E. Motor symptoms

A

D. Repetitive speech

417
Q

Which of the following investigations is diagnostic but potentially dangerous in bow hunter stroke?
● A. CTA
● B. CTV
● C. MRV
● D. Dynamic cerebral angiography
● E. Digital subtraction angiography

A

D. Dynamic cerebral angiography

418
Q

Which of the following is the most commonly involved sinus in cerebral venous thrombosis?
● A. Straight sinus
● B. Superior sagittal sinus
● C. Inferior sagittal sinus
● D. Occipital sinus
● E. Cavernous sinus

A

B. Superior sagittal sinus

419
Q

In dural sinus thrombosis, postcontrast CT shows which radiologic sign near torcular herophili?
● A. Sunburst
● B. Popcorn
● C. String
● D. Delta
● E. C shaped

A

D. Delta

420
Q

The type of graft used for EC/IC bypass depends on preoperative determination of amount of flow augmentation necessary, the size of the recipient graft, and the availability of donor vessel. What is the rate of flow through the radial artery graft?
● A. 15 to 25 mL/min
● B. 25 to 40 mL/min
● C. 40 to 70 mL/min
● D. 60 to 120 mL/min
● E. 70 to 140 mL/min

A

C. 40 to 70 mL/min

421
Q

Which of the following are the risk factors of spontaneous intracerebral hemorrhage in adults?
● A. Age: the incidence increases after 55 years of age and doubles with each decade of age until the age of more than 80 years when incidence is 25 times that during previous decade
● B. Gender: more common men
● C. Previous stroke
● D. Alcohol consumption
● E. Cigarette smoking and street drugs
● F. Liver dysfunction
● G. All of the above

A

G. All of the above

422
Q

Common arterial feeders of ICH include lenticulostriates, thalamoperforators, and paramedian branches of basilar artery. What is the most common site of spontaneous ICH which constitutes about 50%?
● A. Striate boyd (basal ganglia) in which putamen is the most common
● B. Thalamus
● C. Pons
● D. Cerebellum
● E. Cerebral white matter

A

A. Striate boyd (basal ganglia) in which putamen is the most common

423
Q

Lobar hemorrhages are more common in people with high alcohol consumption, and it can involve frontal, parietal, occipital, or temporal lobe. Following are the etiologies of lobar hemorrhage except?
● A. Extension of deep hemorrhage
● B. Amyloid angiopathy
● C. Hemorrhagic tumor
● D. Hemorrhagic transformation of ischemia can never cause it
● E. AVM
● F. Aneurysm

A

D. Hemorrhagic transformation of ischemia can never cause it

424
Q

What is the factor that constitutes up to two-thirds of the cerebellar hemorrhages?
● A. Hypertension
● B. AVM
● C. Aneurysm
● D. Smoking
● E. Diabetes mellitus

A

D. Smoking

425
Q

Cerebral amyloid angiopathy (CAA) is pathologic deposition of beta amyloid protein within the media of small meningeal and cortical vessels without evidence of systemic amyloidosis. Definite diagnosis of CAA can be made only on full postmortem. Which of the following is probably CAA with supporting
pathological evidence for CAA?
● A. Lobar, cortical, or corticosubcortical hemorrhage
● B. Some degree of vascular amyloid deposition in biopsy specimen
● C. Absence of another diagnostic lesion
● D. All of the above

A

D. All of the above

426
Q

Malignant tumors most commonly involving ICH include the following except?
● A. Glioblastoma
● B. Lymphoma
● C. Medulloblastomas and gliomas
● D. Renal cell carcinoma and bronchogenic carcinoma
● E. Metastatic tumors like melanoma or choriocarcinoma

A

C. Medulloblastomas and gliomas

427
Q

Delayed deterioration after the initial hemorrhage is usually due to any combination of the following?
● A. Rebleeding
● B. Edema
● C. Hydrocephalus
● D. Seizures
● E. Increased ICP
● F. All of the above

A

F. All of the above

428
Q

Following statements are correct regarding variation of brain MRI signal characteristics of intraparenchymal blood over time except?
● A. Hyperacute blood is within first 6 hours; it consists of oxyHgb and appears isointense on T1 and hyperintense on T2 MRI
● B. Acute is from 6 to 72 hours, which consists of deoxy-Hgb which appears isointense on T1 and hypointense on T2
● C. Early subacute which is from 3 to 7 days; it consists of met-Hgb (intracellular) which is hyperintense on T1 and hypointense on T2 MRI
● D. Late subacute is from 7 to 14 days which consist of met-Hgb (extracellular) which is hyperintense on both T1 and T2 images
● E. Chronic which is more than 14 days and consists of hemosiderin. It appears hyperintense on both T1 and T2 MRI images

A

E. Chronic which is more than 14 days and consists of hemosiderin. It appears hyperintense on both T1 and T2 MRI images

429
Q

ICH scores of 0, 1, 2, 3, 4, 5, and 6 correlate with 30-day mortality of 0, 13, 26, 72, 97, 100, and 100%, respectively. Which of the following are the components of ICH score?
● A. GCS (with score 2 for GCS 3–4, score 1 for GCS 5–12, score 0 for GCS 13–15)
● B. Age (with age above 80 years comprising score 1 while below 80 years it is 0)
● C. Location (1 for infratentorial and 0 for supratentorial)
● D. ICH volume (1 for > 30 mL while 0 for < 30 mL)
● E. Intraventricular blood (1 for presence and 0 for absence)
● F. All of the above

A

F. All of the above

430
Q

Indications for ventriculostomy after ICH include which of the following?
● A. Acute hydrocephalus and management of ICP
● B. For evacuation of ICH in brain parenchyma
● C. For low GCS patients
● D. In patients who are not surgical candidates with large ICH
● E. In patients who cannot tolerate surgery

A

A. Acute hydrocephalus and management of ICP

431
Q

What is the most common site for spontaneous ICH?
● A. Basal ganglia
● B. Thalamus
● C. Pons
● D. Cerebellum
● E. Brainstem

A

A. Basal ganglia

432
Q

What is the source of putaminal hemorrhage in spontaneous ICH?
● A. Lenticulostriate
● B. Thalamoperforators
● C. Basilar artery
● D. Vertebral artery
● E. Extension from cortical ICH

A

A. Lenticulostriate

433
Q

Hemorrhagic transformation of an ischemic stroke where the hemorrhage is extending beyond the margins of the ischemia is categorized as which type?
● A. Type I
● B. Type II
● C. Type III
● D. Type IV
● E. Complex

A

B. Type II

434
Q

The diagnosis of cerebral amyloid angiopathy is best confirmed with which of the following?
● A. Postmortem histopathology
● B. Catheter angiogram
● C. CTA
● D. MRA
● E. MRV

A

A. Postmortem histopathology

435
Q

Which of the following metastatic tumors is not associated with ICH?
● A. Melanoma
● B. Bronchogenic carcinoma
● C. Renal cell carcinoma
● D. Choricarcinoma
● E. Prostate carcinoma

A

E. Prostate carcinoma

436
Q

A patient presented with hemisensory loss following an ICH. What is the most likely location of the ICH?
● A. Thalamus
● B. Basal ganglia
● C. Brainstem
● D. Cerebellum
● E. Putaminal

A

A. Thalamus

437
Q

In case of lobar hemorrhage, contralateral hemiparesis along with hemisensory deficit is associated with which of the following?
● A. Cerebellar
● B. Frontal
● C. Temporal
● D. Parietal
● E. Occipital

A

D. Parietal

438
Q

After ICH, what is the incidence of rebleed within first 3 hours?
● A. 15%
● B. 33%
● C. 45%
● D. 54%
● E. 100%

A

B. 33%

439
Q

After ICH, the size of clot decreases at what rate per day?
● A. 0.25 mm
● B. 0.75 mm
● C. 1 mm
● D. 1.25 mm
● E. 10 mm

A

B. 0.75 mm

440
Q

A 95-year-old patient presented with severe headache followed by seizures and loss of consciousness. The GCS was 7/15. Plain CT of brain revealed a 50-mL ICH in the left parietal region with intraventricular extension. What is the ICH score in
this case?
● A. 2
● B. 3
● C. 4
● D. 5
● E. 6

A

C. 4

441
Q

In an ICH that is hyperintense on T1 and hypointense on T2 MRI, what is the phase of the ICH?
● A. Hyperacute
● B. Acute
● C. Early subacute
● D. Late subacute
● E. Chronic

A

C. Early subacute

442
Q

How long should oral anticoagulant (OAC) use be avoided after OAC-associated ICH inpatients without mechanical heart valves to decrease the risk of recurrent ICH?
● A. For at least 1 week
● B. For at least 2 weeks
● C. For at least 3 weeks
● D. For at least 4 weeks
● E. For at least 5 weeks

A

D. For at least 4 weeks

443
Q

What is the most common cause of spontaneous ICH in young adults?
● A. Ruptured AVM
● B. Arterial hypertension
● C. Ruptured saccular aneurysm
● D. Sympathomimetic drug abuse
● E. Tumor

A

A. Ruptured AVM

444
Q

Intracerebral hemorrhage of the newborn occurs primarily in the premature infants. Alternate terms for this include subependymal hemorrhage, germinal matrix hemorrhage, and periventricular intraventricular hemorrhage. Intraventricular hemorrhage arises from extension of subependymal hemorrhage through ependymal lining of ventricles and occurs in how many cases of subependymal hemorrhage?
● A. 50%
● B. 60%
● C. 70%
● D. 80%
● E. 90%

A

D. 80%

445
Q

The metabolically active germinal matrix is susceptible to hypotension and hypoperfusion which can lead to infarction. The germinal matrix is a valuable watershed zone which is supplied by which artery?
● A. Heubner’s artery from anterior cerebral artery
● B. Terminal branches of the lateral striate arteries from the middle cerebral artery
● C. Anterior choroidal artery from the internal carotid or middle cerebral artery
● D. All of the above

A

D. All of the above

446
Q

What is the pathogenesis of periventricular intraventricular hemorrhage in the preterm infant?
● A. Postnatal hypoxia due to respiratory distress syndrome related to hyaline membrane disease, pneumothorax, or anemia can deprive the metabolically active germinal matrix of oxygen. This ischemia makes them vulnerable to infarction and rupture
● B. Hypercapnia maximally dilates the thin-walled vessels of the germinal matrix. If this is followed by sudden increase in perfusion this can lead to rupture of vessels
● C. Increased venous pressure from any cause like labor or positive pressure ventilation can lead to hemorrhage in germinal matrix
● D. In dehydration followed by rapid resuscitation with hyperosmolar solutions with associated increase in systemic blood pressure, the germinal matrix is at risk of hemorrhage
● E. All of the above

A

E. All of the above

447
Q

Which of the following are risk factors for periventricular intraventricular hemorrhage in premature infants?
● A. Those associated primarily with increased CBF or CPP
● B. Younger gestational age and low birth weight
● C. Acute amnionitis and failure to give antenatal steroids
● D. APGARs score less than 4 at 2 minutes and less than 8 at 5 minutes
● E. Use of recreational drugs by the mother or maternal aspirin use
● F. Smoking by the mother
● G. Acidosis and coagulopathies

A

F. Smoking by the mother

448
Q

Which of the following are the grades of subependymal hemorrhage?
● A. Grade 1 is subependymal hemorrhage
● B. Grade 2 is IVH without ventricular dilatation
● C. Grade 3 is IVH with ventricular dilatation
● D. Grade 4 is IVH with parenchymal hemorrhage
● E. All of the above

A

E. All of the above

449
Q

What can be the steps for prevention of periventricular intraventricular hemorrhage?
● A. Good prenatal care and avoiding preterm delivery with antenatal steroids
● B. Indomethacin and antenatal vitamin K given IM more than 4 hours prior to delivery
● C. Sluicing umbilical cord and delaying umbilical cord clamping by 30 to 120 seconds in premature infants increased hematocrit and decreased PIVH in 5 of 7 studies
● D. Using surfactant
● E. All of the above

A

E. All of the above

450
Q

Following are the pathophysiologic effects of periventricular intraventricular hemorrhage (PIVH) except?
● A. Destruction of germinal matrix and direct injury to neural tissue from hematoma
● B. Reduction of CBF in the whole brain due to elevated ICP
● C. Decreased CPP leads to periventricular leukomalacia and cerebral infarction
● D. Injury to brain stem
● E. Periventricular hemorrhagic infarction, hydrocephalus, and seizures

A

D. Injury to brain stem

451
Q

What is the indication of surgical intervention in a patient with periventricular intraventricular hemorrhage (PIVH)?
● A. Progressive ventriculomegaly
● B. Periventricular hemorrhage
● C. Progressive ventriculomegaly with the OFC crossing percentile curves and clinical evidence of increased ICP
● D. Progressive ventriculomegaly with OFC crossing percentile curves without clinical evidence of increased ICP
● E. None of the above

A

C. Progressive ventriculomegaly with the OFC crossing percentile curves and clinical evidence of increased ICP

452
Q

What are the indications and requirements of insertion of VP shunt or conversion of sub Q reservoir to VP shunt?
● A. Symptomatic hydrocephalus or progressive ventriculomegaly
● B. Infant is extubated (and thus off ventilator)
● C. Infant weight more than or equal to 2,000 g
● D. CSF protein ideally less than 100 mg/dL
● E. No evidence of NEC
● F. All of the above

A

F. All of the above

453
Q

What is the most common cause of spontaneous ICH in young adults?
● A. Ruptured AVM
● B. Arterial hypertension
● C. Ruptured saccular aneurysm
● D. Sympathomimetic drug abuse
● E. Tumor

A

A. Ruptured AVM

454
Q

What is the site of hemorrhage at > 29-week gestational age?
● A. Head of caudate nucleus
● B. Lentiform nucleus
● C. Intraventricular
● D. Cerebellar vermis
● E. Lobar

A

A. Head of caudate nucleus

455
Q

Risk factors for periventricular intraventricular hemorrhage (PIVH) do not include which of the following?
● A. Blood pressure fluctuations
● B. Younger gestational age (GA)
● C. Low birth weight
● D. Acute amnionitis
● E. Antenatal steroids

A

E. Antenatal steroids

456
Q

Regarding ICH in newborns, an intraventricular hemorrhage with ventricular dilation, what is the subependymal hemorrhage grade?
● A. 1
● B. 2
● C. 3
● D. 4
● E. 5

A

C. 3

457
Q

Post periventricular intraventricular hemorrhage (PIVH) hydrocephalus usually occurs for how long after the hemorrhage?
● A. 1 to 3 weeks
● B. 3 days
● C. 5 days
● D. 3 to 5 weeks
● E. 48 hours

A

A. 1 to 3 weeks

458
Q

To allow ventricles to expand to facilitate catheterization, reservoir should not be tapped before inserting a new ventricular catheter for at least how long?
● A. 12 hours
● B. 24 hours
● C. 36 hours
● D. 48 hours
● E. 72 hours

A

B. 24 hours

459
Q

A 60-year-old patient is known case of GBM grade 4. He requires occasional assistance but can take care of most of his needs. What would be his Karnofsky performance score?
● A. 80
● B. 70
● C. 60
● D. 50
● E. 40

A

C. 60

460
Q

A 40-year-old patient had road traffic accident 2 months ago. He performs daily routine in highly familiar environment in a nonconfused but automatic “robot-like” fashion. His skills deteriorate in unfamiliar environment. He lacks realistic planning for future. What would be his Ranchos Los Amigos cognitive score?
● A. Confused agitated
● B. Confused-appropriate
● C. Automatic-appropriate
● D. Purposeful-appropriate
● E. None

A

C. Automatic-appropriate

461
Q

If a patient is having severe disability (conscious but disabled) and his dependence for daily support may be institutionalized, what would be his Glasgow outcome score?
● A. 0
● B. 1
● C. 2
● D. 3
● E. 4

A

D. 3

462
Q

A 30-year-old man had trauma 2 weeks ago. He is unable to walk without assistance and unable to attend to his own bodily needs without assistance. What would be his modified Rankin score?
● A. 5
● B. 4
● C. 3
● D. 2
● E. 1

A

B. 4

463
Q

As for functional independence measure (FIM) for evaluation of disabilities of spinal cord injuries, if a patient requires minimal assistance and can carry out > 75% activities on his or her own what would be the score?
● A. 6
● B. 4
● C. 2
● D. 1
● E. 0

A

B. 4

464
Q

Karnofsky performance scale (KPS) is often used for grading functional status in patients with cancer. What is the KPS score that often identifies patients with a worse prognosis for any given treatment?
● A. < 80
● B. < 70
● C. < 60
● D. < 50
● E. < 40

A

B. < 70

465
Q

Which of the following is correct regarding Karnofsky performance scale in cancer patients?
● A. Score 80 to 100 are able to carry on normal activity and work with no special care needed
● B. Score 50 to 70 are unable to work. They are able to live at home and care for most personal needs with variable assistance required
● C. Score 0 to 30 are unable to care for themselves. They require equivalent of institutional or hospital care and the disease may be rapidly progressing
● D. All of the above

A

D. All of the above

466
Q

Which of the following is incorrect regarding WHO performance score?
● A. Grade 0 is fully active, with no performance restriction as a result of the disease
● B. Grade 1 is restriction in physically strenuous activity. The patient is ambulatory and able to do light work
● C. Grade 2 is unable to perform any activities and nonambulatory
● D. Grade 3 is only able to perform limited self-care
● E. Grade 4 is completely disabled and not able to perform self-care
● F. Grade 5 is dead

A

C. Grade 2 is unable to perform any activities and nonambulatory

467
Q

Ranchos Los Amingos scale is often used in rating disability following what?
● A. Spine injury
● B. Cancer patient
● C. Head injury
● D. Quadriplegia
● E. None of the above

A

C. Head injury

468
Q

Which of the following is correct regarding Ranchos Los Amigos cognitive scale?
● A. Level 1 is no response to pain, touch, sigh, or sound
● B. Level 2 is generalized reflex response to pain
● C. Level 3 is localized response
● D. Level 4 is confused agitated
● E. Level 5 is confused and nonagitated
● F. Level 6 is confused appropriate
● G. Level 7 is automatic appropriate
● H. Level 8 is purposeful appropriate
● I. All of the above

A

I. All of the above

469
Q

Which of the following is correct regarding Glasgow outcome scale extended and original?
● A. Score 1 is dead
● B. Score 2 is vegetative
● C. Scores 3 and 4 are severely disabled
● D. Scores 5 and 6 are moderately disabled
● E. Scores 7 and 8 are good recovery
● F. All of the above

A

F. All of the above

470
Q

Which of the following is incorrect regarding modified Rankin scale?
● A. Grade 0 is no symptoms at all
● B. Grade 1 is no significant disability despite symptoms
● C. Grade 2 is slight disability with unable to carry out all activities
● D. Grade 3 is moderate disability requiring some help
● E. Grade 4 is moderately severe disability and unable to walk without assistance
● F. Grade 5 is severe disability, bedridden, and incontinent
● G. None of the above

A

G. None of the above

471
Q

Of all the factors in Barthel index, what is the most difficult one?
● A. Personal hygiene
● B. Self bathing
● C. Feeding
● D. Toilet
● E. Stair climbing

A

B. Self bathing

472
Q

Following are included in functional independence measure for spinal cord injury except?
● A. Self-care
● B. Sphincter control
● C. Power
● D. Mobility
● E. Locomotion

A

C. Power

473
Q

What does functional independence score of 7 mean?
● A. Modified independence
● B. Complete independence
● C. Minimal assistance
● D. Moderate assistance
● E. Maximal assistance

A

B. Complete independence