Secondary Skin Lesion Flashcards
Dry, rectangular scales that resemble cracked pavement
What is this?
what causes the scales?
Ichthyosis- an autosomal dominant disorder of keratinization that begins in childhood.
It is associated with Atopy (a genetic predisposition to develop allergies)
scaling results from retention of scalw (not proliferation)
tx: moisturizers w/ lacti acid, urea, or alphy hydroxy acids
Red, sharply defined, scaling papules that coalesce to form stable, round to oval plaque
What is the most likely diagnosis?
What allel is associated with this condition?
what is the most common location of this plaque?
Plaque Psoriasis:
HLA-B27
plaques are commonly found on the extensor surfaces
the onset of the disease is bimodal. Early onset = worse clinical course
A sudden onset is highly suspicious for HIV
Small sterile pustules that evolve from a red base on palms and soles. The pustules do not rupture, but turn rusty brown and scaly. They are painful.
most likely diagnosis?
Chronic Recurrance of this condition is associated with?
Localized pustular psoriasis
chronic recurrance is associated with tobacco use
Sudden appearance of innumerable, monomorphic, 2-5 mm psoriasiform papules on the trunk with silvery scale
What is the most likely diagnosis?
What other conditions are associated with these types of lesions?
Gluttate psoriasis
Group A strep pharyngitis and viral infections
This rash occurs in the intertriginous area (groin, axillae, or under the breasts). It is a smooth, red, sharply defined plaque w/ a macerated surface, and often has an odor.
What is the most likely diagnosis?
How can you diagnosis it?
Inverse psoriasis
KOH test if you suspect a superimposed candida infection
How do you treat psoriasis?
- Topical tx:
- Phototherapy
- UVB
- Psoralen plus UVA
- Systemic Tx
- Methotrexate
- cyclosporine
- bioligics
planar, polygonal, purple, papules that are very puritic. The surface shows a lacy reticulated pattern of whitish lines.
What is the most likely diagnosis?
What are these lines called?
Lichen Planus
Wickham’s Striae
How do you treat Lichen Planus?
Treatment
- Sedating antihistamines
- topical steroids (local disease)
- prednisone for generalized skin or erosive mucosal involvement
4.
A red, raised border
What is the most likely diagnosis?
Tinea (fungal) the location determines the rest of the name
foot=pedis
groin= cruris
boy= corporis
face= faciei
hand= manuum
Brown hyperpigmentation, loss of scaling at borders, loss of a well-defined border
What is the most likely diagnosis?
T. incognito. The appearance of the infection changes by the application of topical corticosteroids.
This is found in the axilla and fluoresces red under a wood’s lamp
What is the most likely diagnosis?
Erythrasma
Red-purple eyelid discoloration (heliotrope rash), gottron’s papules (papules on the fingers) and shawl sign.
What is the most likely diagnosis?
this is associated with an increased/decreased risk of malignancy
what type of inflammation is seen with this condition? What type of cell is also associated?
Dermatomyositis
a/w increased risk of malignancy
perimysial inflammation and atrophy w/ CD4+ T cells
What other lab values would we expect with a dx of dermatomyositis?
increased CK
Increased CRP
+ANA, +anti-Jo-1 antibodies
what is the treatment for dermatomyosistitis?
steroids
methotrexate
cyclosporine
hydroxychloraquine
“mechanic’s hands” with Endomysial inflammation with CD8+ T cells
What is the most likely diagnosis?
what other s/s is associated with this disease?
Polymyosistitis
progressive symmetric proximal muscle weakness (shoulders, hips, thighs)
