Secondary Post-Partum Haemorrhage Flashcards

1
Q

What is secondary postpartum haemorrhage?

A

Excessive vaginal bleeding in the period from 24 hours - 12 weeks postpartum

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2
Q

What is the overall incidence of postpartum haemorrhage in the developed world?

A

0.47-1.44%

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3
Q

What are the causes of secondary postpartum haemorrhage?

A
  • Endometritis
  • Retained placental fragments or tissue
  • Abnormal involution of placental site
  • Trophoblastic disease
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4
Q

What is meant by abnormal involution of the placental site?

A

Inadequate closure and sloughing of spiral arteries at the placental attachment site

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5
Q

Is trophoblastic disease common?

A

No, it is very rare

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6
Q

What is the main symptom of secondary PPH?

A

Excessive vaginal bleeding

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7
Q

How does the severity of secondary PPH compare to primary?

A

It is usually not as severe as primary

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8
Q

How might the patient describe the vaginal bleeding in secondary PPH?

A

May complain of spotting on-and-off for days after delivery, with occasional gush or fresh blood

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9
Q

What % of cases of secondary PPH will present with massive haemorrhage?

A

10%

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10
Q

What do the additional clinical features of secondary PPH depend on?

A

The underlying cause

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11
Q

What symptoms might be present with endometritis?

A
  • Fever/rigors
  • Lower abdominal pain
  • Foul smelling lochia
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12
Q

What is lochia?

A

The normal discharge from the uterus following childbirth

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13
Q

What may be found on abdominal examination in secondary PPH?

A
  • Lower abdominal tenderness

- Uterus may still be high

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14
Q

What is lower abdominal tenderness a sign of?

A

Endometritis

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15
Q

What is the uterus being high a sign of?

A

Retained placenta

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16
Q

Why is speculum examination important in secondary PPH?

A

To assess amount of bleeding

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17
Q

What should be done during speculum examination in secondary PPH?

A

High vaginal swab

18
Q

How should secondary PPH be managed if the patient is haemodynamically unstable or bleeding heavily?

A

Call for help and follow resuscitation algorithm

19
Q

Should you establish a cause before resuscitation is commenced in secondary PPH where the patient is haemodynamically unstable or bleeding heavily?

20
Q

What laboratory tests should be done in secondary PPH?

A
  • FBC
  • Urea and electrolytes
  • C-reactive protein
  • Coagulation profile
  • Group and save
  • Blood cultures (if pyrexial)
21
Q

How might a pelvic ultrasound be helpful in secondary PPH?

A

Can assist in diagnosis of retained placental tissue

22
Q

What is the problem with diagnosing retained placental tissue on ultrasound in secondary PPH?

A

The over-diagnosis of retained placental tissue on ultrasound can lea to unnecessary surgical intervention

23
Q

What is a pelvic ultrasound good regarding retained placental tissue?

A

It has a good negative predictive value, and so is helpful in excluding the diagnosis

24
Q

What is the mainstay of treatment for secondary PPH?

A
  • Antibiotics

- Uterotonics

25
What antibiotics are given in secondary PPH?
Combination of ampicillin and metronidazole
26
What antibiotic can be used as an alternative to ampicillin in secondary PPH if the patient is penicillin allergic?
Clindamycin
27
What antibiotic may be added to the regime in secondary PPH?
Gentamicin
28
When might gentamicin be added to the antibiotic regime in secondary PPH?
In cases of endomyometritis (tender uterus) or overt sepsis
29
Give 4 examples of uterotonics that can be used in secondary PPH
- Syntocinon - Syntometrine - Carboprost - Misoprostol
30
What is syntocinon?
Oxytocin
31
What is syntometrine?
Oxytocin and ergometrine
32
What is carboprost?
Prostaglandin F2
33
What is misoprostol?
Prostaglandin E1
34
When might surgical measures be taken in secondary PPH?
In excessive or continuous bleeding
35
What surgical measure may be effective in secondary PPH in continuing haemorrhage?
Insertion of balloon catheter into uterus
36
What are the components of management of massive secondary PPH?
- Communication - Resuscitation - Monitoring and investigation - Arresting the bleeding
37
How should the bleeding be stopped in massive secondary PPH?
Using ureterotonics/surgical measures, depending on suspected cause
38
What does any surgical evacuation of retained products of conception carry a high risk of?
Uterine perforation
39
Why does surgical evacuation of retained products of conception carry a high risk of uterine perforation?
Because the uterus is softer and thinner postpartum
40
Who should the surgical evacuation of retained products fo conception involve?
A senior obstetrician for planning and delivery of surgery