SDL 🧑💻 Flashcards
1
Q
what is the total Ca concentration in blood?
A
The total Ca concentration in blood is normally 10mg/dl.
2
Q
what are the forms of Ca in blood?
A
3
Q
what controls serum Ca?
A
- Intestine
- kidney
- Bone
4
Q
what causes balance in ca concentration in blood?
A
intestinal absorbtion Vs. urinary execretion
5
Q
where is Positive Ca2+ balance seen?
A
- Seen in growing children.
- Intestinal Ca2+ absorption exceeds urinary excretion, and the excess is deposited in the growing bones.
6
Q
where is Negative Ca2+ balance seen?
A
- Seen in pregnant or lactating women.
- Intestinal Ca2+ absorption is less than Ca2+ excretion, and the deficit comes from the maternal bones.
7
Q
A
8
Q
A
9
Q
what is Familial hypocalciuric hypercalcemia (FHH)?
A
Autosomal dominant disorder with decreased urinary Ca2+ excretion and increased Serum Ca2+
10
Q
what causes Familial hypocalciuric hypercalcemia (FHH)?
A
Caused by inactivating mutations of the Ca2+-sensing receptors that regulate PTH secretion.
11
Q
vitamin D metabolism
A
12
Q
what happens in case of decrease in Vit D?
A
- Decreased vit D in children»_space; rickets
- Decreased Vit D IN adult»_space; osteomalcia
