Screening Tests For Blood Disorders Flashcards
PT or international normalized ratio (INR) abnormalities indicated
Extrinsic + common deficiency/inhibition XII, X, V, II, I
PT or international normalized ratio (INR) reference range
12-16 sec (PT)
1.0-1.3 (INR)
PT or international normalized ratio (INR) common cause of disorder
Liver disease, warfarin therapy, DIC
APTT/PTT with Kaolin/Kaolin Cephalin clotting time reference range
23-31 s
APTT/PTT with Kaolin/Kaolin Cephalin clotting time abnormalities indicated
Intrinsic + common deficiency/inhibition XII, IX, VIII, X, V, II, I
APTT/PTT with Kaolin/Kaolin Cephalin clotting time common cause of disorder
Liver disease, heparin therapy, VIII, IX, DIC
Thrombin time (TT) reference range
14-16s
Thrombin time (TT) abnormalities indicated
Deficiency/abnormal I, inhibition of II by heparin or FDPs
Thrombin time (TT) common cause of disease
DIC, heparin therapy, fibrin clot therapy
Fibrin degradation products (FDPs) or Fibrin Split products reference range
<10mg/mL
Fibrin degradation products (FDPs) or Fibrin Split products abnormalities indicated
Accelerated destruction of fibrinogen
Fibrin degradation products (FDPs) or Fibrin Split products common cause of disorder
DIC (disseminated intravascular coagulation)
Bleeding time reference range
3-9 minutes
Bleeding time abnormalities indicated
Abnormal platelet function
Bleeding time common cause of disorder
Aspirin, uremia, Von willebrand disease