Regulatory Protein Activities Flashcards
0
Q
Protein C
A
Activated by thrombomodulin-bound thromin
Serine protease
1
Q
Von willebrand factor
A
Associated with sub endothelial CT: serves as bridge between platelet glycoproteins GPIIb/IIIa and collagen
GPIa causes platelet to change shape
GPIb causes changes in platelet membrane that expose GPIIb and GPIIIa
2
Q
Protein s
A
Cofactor; binds activated protein C
3
Q
Thrombomodulin
A
Endothelial cell receptor: binds thrombin
4
Q
Antithrombin III
A
Most important coagulation inhibitor; also called a serpin
Controls activities of IIa, factors IXa, Xa, XIa and XIIa
