Scleroderma Antibodies Flashcards
1
Q
What are the antibodies associated with DcSSc?
A
Anti-Scl70 and Anti-topoisomerase I
- Speckled
- Associated with ILD
Anti RNA Pol I, II, III
- Speckled
- Associated with skin and renal changes
2
Q
What are the antibodies associated with LcSSc?
A
Anti- centromere
- Associated with PAH
3
Q
What are the antibodies associated with overlap syndromes and myositis?
A
Anti-PM and Anti-Scl
4
Q
Which antibodies are speckles?
A
Anti-Scl70
Anti-topoisomerase I
Anti RNA Pol I, II and III
5
Q
Which antibodies can be speckled and nucleoar?
A
Anti RNA Pol I, II and II
6
Q
Which antibodies are associated with ILD?
A
Anti-Scl70 and Anti-topoisomerase I
7
Q
Which antibodies are associated with skin and renal disease?
A
Anti RNA Pol I, II and III
8
Q
Which antibodies are associated with PAH?
A
Anti-centromere
