Science Of Medicines Flashcards
What is the difference between a medicine and a drug
A medicine is what is administered to a patient
A drug is the active substance present in the dosage form
What must a drug do in order to be useful
Reach its site of action
What is biopharmaceutics
Study of the factors which modify the performance of pharmaceutical dosage forms and how this information can be used to optimise drug delivery systems
What is pharmacodynamics
What the drug does to the body
What is pharmacokinetics
What the body does to the drug
What can pharmacokinetics be characterised into
ADME
absorption
Distribution
Metabolism
Excretion
What is bioavailability
A quantitive measure of the amount of a drug that reaches its site of action and the rate at which it gets there
How to measure a drugs presence at the site of action (given the drug has been absorbed into the systemic circulation via an injection or oral administration)
What kind of medicines would this not be useful to measure?
Taking a blood test
Eye drops or creams as not much of the drug would reach the blood stream