Science Flashcards

1
Q

order of neurovascular bundle in ribs (from top to bottom)

A

vein
artery
nerve

(VAN)

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2
Q

where are the neurovascular bundles in the ribs

A

costal groove (underneath rib)

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3
Q

what is the bundle of fibres above each rib called

what is the order of the fibres (from top to bottom)

A

collateral bundle

nerve
artery
vein

(NAV)

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4
Q

how many holes does the right hilum have

what are they for

A

5 (bc RIGHT has 5 letters)

2 veins
2 arteries
1 lymphatic vessel

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5
Q

how many holes does the left hilum have

what are they for

A

4 (bc LEFT has 4 letters)

2 veins
1 artery
1 lymphatic vessel

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6
Q

what does failure of phagocytosis cause

A

granulomatous disease

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7
Q

type I hypersensitivity definition example

A

allergy (type I = A = Allergy)

eg food allergy, atopy, eczema

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8
Q

type II hypersensitivity definition and examples (4)

A

direct cell killing via antibodies (type II = B = via antiBodies)

eg graves, myasthenia graves, gullian barr, good pastures

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9
Q

type III hypersensitivity definition and example (1)

A

immune complement activation (type III = C = Complement)

eg lupus

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10
Q

type IV hypersensitivity definition and example (4)

A

delayed type hypersensitivity (type IV = D = Delayed)

eg poison ivy, sarcoidosis, coeliac, TB, T1DM

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11
Q

what is V/Q ratio

A

ventilation/perfusion ratio

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12
Q

what is V/Q at the top of the lungs

which is better

A

high

ventilation is better

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13
Q

what is V/Q at the bottom of the lungs

which is better

A

low

perfusion is better

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14
Q

what shape is a haemoglobin oxygen curve

A

sigmoidal

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15
Q

what shape is a myoglobin oxygen curve

A

logarithmic

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16
Q

how is CO2 mainly transported in the blood

A

bicarbonate

17
Q

what do parasympathetics do to bronchi

A

contract them = bronchoconstriction

18
Q

which receptor and G protein are responsible for bronchoconstriction

A

M3

Gq

19
Q

which receptor and G protein are responsible for bronchodilation

A

B2

Gs

20
Q

what do sympathetics do to bronchi

A

relax them = bronchodilation

21
Q

resp side effect of steroids

A

hoarse voice

22
Q

if FEV1/FVC is normal but FEV1 and FVC are both reduced, what kind of resp problem does the patient have

example

A

restrictive (both lungs and airways are fuckoed)

pneumonia

23
Q

if FEV1/FVC is reduced bc FEV1 is reduced but FVC is normal, what kind of resp problem does the patient have

example

A

obstructive (FVC is normal = lungs are fine, problem is getting to the lungs)

asthma

24
Q

what type of spirometry result does COPD present with

A

restrictive AND obstructive

FEV1 reduced
FVC reduced
FEV1/FVC reduced

25
Q

what type of resp failure has decreased O2 but normal CO2

examples

A

type 1

pneumonia, ARDS

26
Q

what type of resp failure has decreased O2 and high CO2

example

A

type 2

COPD

DONT GIVE O2!

27
Q

ABGs

pH slightly high (low H+)
CO2 low
HCO3 low

what is the problem

example

A

partially compensated respiratory alkalosis

hyperventilation, pregnancy, PE

28
Q

ABGs

pH low (high H+)
CO2 high
HCO3 normal

what is the problem

example

A

uncompensated respiratory acidosis

COPD, asthma, opiate overuse

29
Q

ABGs

pH normal (was previously low, high H+)
CO2 low
HCO3 low

what is the problem

example

A

fully compensated metabolic acidosis

DKA, acid ingestion, renal failure, peptic ulcer

30
Q

ABGs

pH high (H+ low)
HCO3 high
CO2 normal

what is the problem

example

A

uncompensated metabolic alkalosis

vomiting, alkali ingestion, vit K deficiency

31
Q

which lung hilum sites higher than the other

A

left bc of heart