Schoenwald - Rabies Flashcards
rabies is classified as a __virus
rhabdo
rabies is common in __ animals
terestial
animals that walk
4 animals that are considered highly rabid
bats
foxes
skunks
raccoons
incubation period of rabies
weeks to months
typically 2-4 weeks
sx of rabies (4)
flu like prodrome
confusion
fever
hydrophobia
changes in behavior
fatality rate of rabies if sx develop
100%
preexposure rabies immunization (2)
imovax
OR
rabavert
historically, imovax and rabavert were a _ shot series given on days
__
0, 7, 21 or 28
new 2022 rec for preexposure rabies is a __ shot series
given on days __
2
0, 7
schedule for imovax or rabavert for post exposure
2 immunizations on days: 0 and 3
post exposure prophylaxis for rabies for someone who has received pre exposure prophylaxis (ex. vet) includes
2 doses of imovax OR rabavert on days 0 and 3
post exposure prophylaxis for someone who has not had pre exposure prophylaxis
HRIG on day 0
PLUS
4 doses of rabies vaccine on days 0, 3, 7, 14
human rabies immune globulin is __ immunization
passive
what is passive immunization
ready to go abs → works fast
dosing for human rabies immune globulin
20 u/kg
available doses of human rabies immune globulin
150 units/mL
300 units/mL
ex dosing of HRIG for for 82 kg person
82 kg x 20 u = 1,640 mL
1,640 u/150 u/mL = 10.9 u → 11 mL
HRIG is most effective if infiltrated at
the bite site
alternately can be given IM
when is HRIG given
day 0
