Schoenwald Flashcards
what do you think when you see bone/joint pan and elevated APR
osteomyelitis
what are the 2 types of osteomyelitis
acute
chronic
suspect osteomyelitis if (2)
- bone can be probed w. swab from wound site
- wound > 6 weeks duration
what are 2 imaging choices for osteomyelitis
- plain film xray
- MRI if xray negative and high suspicion for osteomyelitis
osteomyelitis is __ or
__ infxn of the bone
bacterial
fungal
what are the 3 sources of osteomyelitis
- hematogenous
- invasion from contiguous focus of infxn
- skin breakdown
what are 5 hematogenous sources of ostomyelitis
- bacteremia
- sickle cell anemia
- elderly
- IVD users
- DM
a diabetic foot infxn is an example of which source of osteomyelitis
invasion from contiguous focus of infxn
vascular insufficiency or trauma is an example of which type of osteomyelitis
skin breakdown
what bacteria is associated w. SSA and osteomyelitis
salmonella
what test do you order for definitive confirmation of osteomyelitis
bone culture
what is the main organism associated w. osteomyelitis in non SSA patients
s. aureus
osteomyelitis in DM pt’s is often
polymicrobial
what bacteria would you suspect if a pt had osteomyelitis from a nail through the foot
pseudomonas
MRI will usually show infxn how long after clinical symptoms
7-15 days
what do you think when you see an MRI w. cortical erosion, periosteal rxn, lucency, or osteolysis
osteomyelitis
what are the treatment steps for osteomyelitis
- debridement of bone
- minimum 6 weeks abx targeted to organism
what is the minimum amt of time for abx in osteomyelitis
6 weeks
what is the empiric abx of choice for osteomyelitis
vanco 1 gm IV q 12 hr +/- Rifampin
PLUS
Cefriaxone 2 gm IV q 24 hr
after cultures, what abx should you use for MSSA
Nafcillin 2 gm iv q 4 hr
OR
Cefazolin 2 gm IV q 8 hr
what is the abx of choice if culture shows MRSA
vanco 1 gm IV q 12 hr +/- rifampin 300-400 mg po tid
what is the abx of choice if osteomyelitis culture shows pseudomonas
Cipro
must also check for foreign body and do tetanus prophylaxis if nail
what is the abx of choice for mild osteomyelitis
doxycycline → good bone penetration
how should you treat osteomyelitis in DM pt
- debride and get cultures
- no empiric therapy → wait for culture to preserve kidneys
what labs should you order for continued monitoring for osteomyelitis
- CBC
- CMP
- APR
what is the mc affected bone in brodie’s abscess
tibia
what is brodie’s abscess
abscess walled off by body’s immune system for years
what are 3 symptoms of brodie’s abscess
- pain
- +/- outward drainage externally
- red and swollen around bone
what is the pathogen associated w. brodie’s abscess
s. aureus
what is this showing
brodie’s abscess
what might brodie’s abscess look like on xray
small luscent area
what are the 3 causes of infectious arthritis (septic arthritis)
- direct inoculation of joint space by bacteria
- contiguous spread
- bacteremia
- previously damaged joint
what is the most common cause of infectious (septic) arthritis
bacteremia
what 2 pt populations are vulnerable to infectious (septic) arthritis from a previously damaged joint
- RA
- prosthetic joint
what joints are mc in infectious (septic) arthritis
knee
hip
shoulder
spread of infectious arthritis is usually
monoarticular
what are 4 symptoms of infectious (septic) arthritis
- fever
- pain at joint
- erythema of joint
- impaired ROM
- monoarticular
what is the most common cause of infectious (septic) arthritis in young, healthy, sexually active pt’s
gonorrhea
what is the op tx for infectious (septic) arthritis
doxycycline
OR
Bactrim
→ to cover MSSA and MRSA
what is the tx for infectious (septic) arthritis if only MSSA isolated
Nafcillin
OR
Keflex
besides abx, how else should you treat infectious (septic) arthritis
fluid drainage
what is reactive arthritis
rxn to infectious arthritis outside of the active infxn
what kind of process is reactive arthritis
delayed inflammatory