Schizophrenia: Week 6 Flashcards
define Schizophrenia
Splitting of the mind due to a disruption in coordination of cognition, emotions and drives, creating fundamental disturbances of:
Schizophrenia symptoms list 2
Lasting 6 months +
Not due to the effects of a general medical condition or drug
Delusions
Hallucinations
Disorganized speech/thought disorder
Characteristics of schizophrenia
Onset of active psychosis: Men 18-25, women: 25-45
10-15% die by suicide,
65% are long term
15-25% Recover
Is Schizophrenia a disorder or a syndrome?
Syndrome
No single psychosis gene or uniformly
Results from interaction of :
genetics and env/meds
old finds vs new findings
NOW: Inc. and prev varies
affects gender differently
incidence increased
high rates in dev countries
Predisposing factors
rheumatoid arthritis rare
season of birth
ob Problems
maternal stress
Schizophrenia aggregates strongly in families
Although family history is the strongest risk factor, only 10% of cases have a first degree relative
are rates higher in lower SES?
yes , 3x higher
time trends in schizophrenia ?
Some evidence that schizophrenia increased since 19th century, due to increased life expectancy and modernization
Evidence suggests that neuroleptics did not dramatically improve treatment outcomes