Schizophrenia (AO1) Flashcards
What is the most common form of biological treatment for SZ? What are the two types?
Drug therapy. Typical antipsychotics, atypical antipsychotics
What is a typical antipsychotic? Typical administration and dosage?
Chlorpromazine. Tablets, syrup or injection and up to 1000mg can be taken daily.
What makes the typical antipsychotic a dopamine antagonist?
They reduce the action of a neurotransmitter by blocking dopamine receptors within the synapses, therefore reducing the action of dopamine
What other useful quality has Chlorpromazine got?
Sedative
What symptoms does Chlorpromazine relieve?
Positive such as hallucination
Are antipsychotics taken short or long-term?
Both, depends on patient’s response to the medication
What is the aim of atypical antipsychotics?
To improve the effectiveness of symptom suppression whilst minimising side effects
Name one atypical antipsychotic and its dosage/administration?
Clozapine. Syrup or tablets, 300 - 450mg a day.
How do atypical antipsychotics work differently?
Bind to dopamine receptors, BUT also serotonin and glutamate receptors too. Therefore, it can also help improve one’s mood and reduce symptoms of depression and anxiety.
Define CBT
Cognitive behavioral therapy happens within groups or individuals between 5 - 20 sessions. Aims to help patients identify irrational thought patterns.
How does CBT help?
Can help patients make sense of (rationalise) their delusions and hallucinations but also how they impact behaviour and feelings.
What is an issue with Clozapine?
Can’t be injected as it can cause the blood poisoning condition agranulocytosis
What is an alternative to Clozapine? Why?
Risperidone as people were starting to die from agranulocytosis. Also a better binder and does so strongly
What does family therapy aim to do?
Improve communication between family members to reduce EE. This means the patient’s stress levels should lower and would reduce the chances of relapse
How does the DSM-5 classify a diagnosis of SZ?
One positive symptom MUST be present
How does the ICD-10 classify a diagnosis of SZ?
Two or more negative symptoms