Schizophrenia and other Psychotic disorders (Hill) Flashcards

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1
Q

Onset of schizophrenia? Precipitating events? Role of marijuana?

A

Onset: peak time of onset at late adolescence and early adulthood

Precipitating: Psychosocial stressors, traumatic events, drug and alcohol abuse

Cannabis use increases risk 6x (esp adolescents)

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2
Q

Prognosis with Positive symptoms? Prognosis with Negative symptoms?

A

Positive symptoms: Better prognosis

Negative symptoms: Poor prognosis

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3
Q

Delusions, hallucinations, catatonia, and agitation are what kind of symptoms in schizophrenia?

A

positive

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4
Q

Schizophrenia FORM of thought?

A
  • Loosening of associations –> Preoccupation with invisible forces
  • Poverty of content and speech
  • Thought blocking –> internal interruption in pts speech/thoughts
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5
Q

Schizophrenia CONTENT of thought?

A

Delusions of persecution/reference/influence

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6
Q

Schizophrenia PERCEPTUAL DISORDERS?

A

Hallucinations (auditory/visual-shadows)

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7
Q

Affective flattening, apathy, social withdrawal, anhedonia, poverty of thought, and content of speech are what type of symptoms in schizophrenia?

A

Negative

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8
Q

How long must symptoms be present for dx of schizophrenia?

A

6 months

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9
Q

For DSM 5 dx criteria “A” for schizophrenia, you must have 2 or more of what for most of 1 month?

A
  • Delusions
  • Hallucinations
  • Disorganized speech
  • Grossly disorganized or catatonic behavior
  • Negative symptoms
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10
Q

Single leading cause of death in schizophrenia pts?

A

Suicide –> attempts occur in 20-50% of pts

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11
Q

What drug may reduce risk of suicide attempt in schizophrenia?

A

Clozapine (watch for neutropenia)

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12
Q

What drug type for tx of catatonic disorder in schizophrenia pts?

A

Benzos

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13
Q

IM injx of these drugs for acute psychosis:

A

1st gen antipsychotics

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14
Q

Adverse effects of 1st gen antipsychotics?

A
  • EPS symptoms

- Neuroleptic malignant syndrome

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15
Q

Concerning side effect of 2nd gen antipsychotic Clozapine?

A

Agranulocytosis

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16
Q

Concerning side effect of 2nd gen antipsychotic Ziprasidone?

A

QTc prolongation

17
Q

This disorder characterized by:

  • UNINTERRUPTED period of illness with either a major depressive episode or manic episode concurrent with symptoms that meet criterion A for schizophrenia
  • Same period of illness, have been delusions or hallucinations for AT LEAST 2 WEEKS in the absence of prominent mood symptoms
A

Schizoaffective disorder

18
Q

This disorder dx by presence of at least the following:

  • Delusions
  • Hallucinations
  • Disorganized speech
  • Grossly disorganized or Catatonic behavior

-Also, duration of an episode of the disturbance is AT LEAST 1 DAY and NO MORE THAN 1 MONTH, with eventual return to premorbid level of functioning

A

Brief psychotic disorder

19
Q

This disorder characterized by:

  • Meets criteria A, D, and E for schizophrenia
  • An episode of the disorder lasts AT LEAST 1 MONTH but LESS THAN 6 MONTHS
A

Schizophreniform

20
Q

This disorder characterized by:

  • Delusions (not always “non bizarre”, i.e. involving situations that could occur in real life such as being followed, poisoned, or infected, having a disease, being loved at a distance) of AT LEAST 1 MONTHS DURATION
  • Has never met criterion A for Schizophrenia (for more than a few hrs)
  • Apart from impact of delusion, functioning is not impaired and behavior is not odd or bizarre
A

Delusional disorder

21
Q

If Schizophrenia, think __ months

If Schizophreniform, think __ months

If Brief Psychotic Disorder, think __ months

A

Schizophrenia= > 6 months

Schizophreniform= 1-6 months

Brief psychotic disorder= <1 month

22
Q

On the schizo Spectrum, this one is a pt who is very introverted and voluntarily withdraws from social interactions

A

Schizoid

23
Q

On the Schizo spectrum, this one is a pt with schizoid symptoms + magical thinking and odd behavior

A

Schizotypal

24
Q

On the Schizo spectrum, this one is a pt with Schizotypal + Psychosis

A

Schizophrenia

25
Q

On the Schizo spectrum, this one is a pt with Schizophrenia + Mood disorder

A

Schizoaffective

26
Q

When is hospitalization necessary?

A

If pt is threatening

27
Q

Which SGA’s can cause weight gain?

A

the “-pines”

  • ClozaPINE
  • OlanzaPINE