Schizophrenia and other Psychotic disorders (Hill) Flashcards
Onset of schizophrenia? Precipitating events? Role of marijuana?
Onset: peak time of onset at late adolescence and early adulthood
Precipitating: Psychosocial stressors, traumatic events, drug and alcohol abuse
Cannabis use increases risk 6x (esp adolescents)
Prognosis with Positive symptoms? Prognosis with Negative symptoms?
Positive symptoms: Better prognosis
Negative symptoms: Poor prognosis
Delusions, hallucinations, catatonia, and agitation are what kind of symptoms in schizophrenia?
positive
Schizophrenia FORM of thought?
- Loosening of associations –> Preoccupation with invisible forces
- Poverty of content and speech
- Thought blocking –> internal interruption in pts speech/thoughts
Schizophrenia CONTENT of thought?
Delusions of persecution/reference/influence
Schizophrenia PERCEPTUAL DISORDERS?
Hallucinations (auditory/visual-shadows)
Affective flattening, apathy, social withdrawal, anhedonia, poverty of thought, and content of speech are what type of symptoms in schizophrenia?
Negative
How long must symptoms be present for dx of schizophrenia?
6 months
For DSM 5 dx criteria “A” for schizophrenia, you must have 2 or more of what for most of 1 month?
- Delusions
- Hallucinations
- Disorganized speech
- Grossly disorganized or catatonic behavior
- Negative symptoms
Single leading cause of death in schizophrenia pts?
Suicide –> attempts occur in 20-50% of pts
What drug may reduce risk of suicide attempt in schizophrenia?
Clozapine (watch for neutropenia)
What drug type for tx of catatonic disorder in schizophrenia pts?
Benzos
IM injx of these drugs for acute psychosis:
1st gen antipsychotics
Adverse effects of 1st gen antipsychotics?
- EPS symptoms
- Neuroleptic malignant syndrome
Concerning side effect of 2nd gen antipsychotic Clozapine?
Agranulocytosis