Schizophrenia Flashcards

1
Q

prevelence of schitzo, age of onset, gender difference, comorbity, cost

A

<1%
late teens to mid 30s
men get it earlier, women have later onset
substance abuse problems, personality disorders
costs are very high w hospitilization

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2
Q

3 active phase symptoms of schitzo

A

positive- displays of abnormal behaviour, delusions
disorganized- affect speech and behaviour
negative- (deficits) in speech, motivation

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3
Q

symptoms of schitzo

A

delusions

  • -persecution (hes out to get me)
  • -gandiose
  • -ideas of reference (taking personal sig to enviroment)

Hallucinations

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4
Q

what area of the brain is more active with auditory hallucinations

A

Brocas area

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5
Q

how is speech affected with schitzo

A

-disorganized
loose association- switching from topic to topic
tangentiality- may ask q and get unrelated answer
incoherent- very hard to understand what person is sayin

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6
Q

how is behaviour affected w schitzo

A

lack of goal directed behaviour

catatonic symptoms

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7
Q

Negative symptoms of schitzo

A

flat affect- person does not show emotion
avolition- no initiative, no energy, lack of interest
alogia- vacent speech (y/n answers)
anhedonia- no pleasure
asociality- few friends

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8
Q

other symptoms of schitzo

A

inapropriate affect
low mood
switch sleep wake cycles
impairments w memory, slower processing speed

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9
Q

what do u need to be diagnosed w schitzo

A
at least one of:
delusions
hallucinations
disorganized speech
plus
grossly disorganized
negative symptoms
social/occupational dysfunction
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10
Q

where the subtypes removed in dsm 5

A

yes

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11
Q

catatonia specifiers

A

Motoric immobility- adopting strange position
waxy flexibility- another person putting u in a weird pos
decreased engagement w others
excessive motor activity
echolalia- repatition of words
echopraxia- repatition of movements

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12
Q

further classification of schitzo

A

isidious vs acute
poor vs good premorbid
type 1: positive symptoms
type 2: negative symptoms

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13
Q

dopamine hypothesis

A

excess dopamine (D2 receptors)

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14
Q

evidence of dopamine hypothesis

A
  1. antagonists (neuroleptics) work
  2. Negative side effects of neuroleptics are similar to parkinsons
  3. amphetamines
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15
Q

evidence that its not the dopamine hypothesis

A
  • dopamine antagonists dont always work
  • dopamine blocked right away, but can take time for therapeutic effect
  • dopamine antagonists work better on positive symptoms
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16
Q

Brain structure with schitzo

A
  • ventricle enlargement

- hypofrontality of prefrontal cortex

17
Q

social class and schitzo (sociogenic and social selection hypothesis)

A
higher rates among lower class
sociogenic (more stress--> schitzo)
social selection ( schitzo--> lower class)
18
Q

early forms of treatment for schitzo

A
  • insulin coma therapy
  • profrontal lobotomy
  • ECT
19
Q

Treatment: antipsychotic drugs (2 types and side effects)

A

conventional
-mostly target positive symptoms
side effects (tardive dyskinesia, akinesia, complience)

Atypical
less side effects

20
Q

some psychosocial interventions

A

-social skills training
-psychoeducation/ family therapy
phychotherapy

21
Q

schizophreniform disorder

A

same symptoms as schitzo but less than 6months

22
Q

Brief psychotic disorder

A
one of (hallucinations, delusions, disorganized speech)
for 1 day to one month
23
Q

schitzoaffective disorder

A

mood symptoms + psychotic symptoms

24
Q

delusional disorder

A

nonbizare delusions

25
Q

shared psychotic disorder

A

delusion in a person who is close to someone w a psychotic disorder