Schizophrenia Flashcards
1
Q
In order to diagnose schizophrenia, which symptoms do you only need one of?
A
- Thought insertion/ broadcasting/ withdrawal
- Delusions: thoughts/action influenced by external forces
- Hallucinatory voices: running commentary or 3rd person
- Other delusions
2
Q
In order to diagnose schizophrenia, which symptoms do you need two of?
A
- Persistent hallucinations: any modality
- Tangential thoughts/ knights move thinking
- Catatonic behaviour
- Negative symptoms
3
Q
Which negative symptoms may be present in schizophrenia?
A
Apathy
Paucity of speech
Blunting
Incongruity of affect
4
Q
What is the first line treatment for newly diagnosed schizophrenia?
A
Second generation antipsychotics
- Olanzapine
- Quetiapine
- Risperidone
5
Q
What is the most popular medication for treatment-resistant schizophrenia?
A
Clozapine
6
Q
What is the risk of Clozapine?
A
Agranulocytosis risk 0.8% in 1st year of treatment
7
Q
What are the common side effects of antipsychotic medications?
A
Extrapyramidal SEs Hyperprolactinaemia Sexual dysfunction Weight gain Diabetes mellitus Cardiovascular Daytime drowsiness Reduced seizure threshold