Schizophrenia Flashcards
Which SGAs cause the least weight gain?
- Aripiprazole
2. Ziprasidone
Which SGA causes the most weight gain?
Olanzapine
Which antipsychotic is associated with the highest risk of causing EPS?
Haloperidol
Which FGA has the highest risk of OT prolongation?
Thioridazine
What is the cutoff ANC and WBC for clozapine initiation?
WBC < 3500
ANC < 2000
Which anti-epileptic medication has been shown to decrease concentration of antipsychotic medications?
CBZ
What GI motility agent may increase the risk of EPS in patients on antipsychotics?
Metoclopramide
What is the preferred therapy for tar dive dyskinesia?
- Stop the agent
2. May try Clozapine
Smoking can decrease the concentration of which antipsychotic medications?
- Olanzapine
- Asenapine
- Haloperidol
Name two moderate-potency FGAs:
- Loxapine
2. Perphenazine
Which FGS causes the most weight gain?
Chlorpromazine
What are the ADA recommendations for frequency of monitoring weight and BMI after baseline in patients taking antipsychotics?
BMI monitoring for the first 3 months, then quarterly thereafter
What is the dosage conversion for haloperidol when switching from oral to injectable (depot)?
10-15 x oral dose
Which drugs require an overlap of oral medication when switching from oral to injectable (depot)?
- Risperidone
2. Aripiprazole
Which SGA is only available as a sublingual tablet?
Asenapine
