Schizophrenia Flashcards

1
Q

criteria for dx

A

2 or more of following for significant portion of one month period. at least one must be 1, 2, or 3:

  1. delusions
  2. hallucinations
  3. disorganized speech
  4. grossly disorganized or catatonic behavior
  5. negative symptoms
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

how long must signs of disturbance continue

A

6 months

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

reasons for other psychotic disorders being ruled out

A
  1. no major depressive or manic episodes have occurred concurrently with active phase sx
  2. if mood episodes have occued, they have been present for minority of total duration of active and residual periods of illness
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

NT implicated

A

excess DA or DA terminals, sensistivity

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

stupor

A

no psychomotor activity

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

waxy flexibility

A

slight, even resistance to positioning by examiner

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

catalepsy

A

passive induction of posture held against gravity

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

mutism

A

no or very little verbal response

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

negativism

A

opposition or no response to instructions or external stimuli
doing opposite of what is asked

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

posturing

A

spontaneous and active maintenance of posture again gravity

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

stereotypy

A

repetitive abnormally frequent non goal directed movement

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

echolalia

A

mimicking another’s speech

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

echopraxia

A

mimicking another’s movements

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

brief psychosis time frame

A

at least one day and less than one month

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

brief psychotic trigger

A

sudden onset
may or may not be preceded by severe stressor
full return to premorbid level of functioning

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

schizophreniform time frame

A

more than one month, less than 6 months

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

schizoaffective disorder time frame

A

along with mood disorder, presence of hallucinations and or delusion occur for at least 2 weeks, but in absence of major mood episode.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
18
Q

positive symptoms categories

A

content of thought
form of thought
perception
sense of self

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
19
Q

negative symptom categories

A
affect
volition
interpersonal functioning and relationship to external world
psychomotor behaviour
associated features
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
20
Q

content of thought types

A

delusions
religiosity
paranoia
magical thinking

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
21
Q

delusion types

A
persecution
grandeur
reference
control or influence
somatic
nihilistic
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
22
Q

persecutory

A

person feels threatened, other intend to harm

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
23
Q

grandeur

A

exaggerated feeling of importance, power, knowledge, identity

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
24
Q

delusions of reference

A

all event within environment are related to him/herself

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
25
ideas of reference
less rigid than delusions of reference. ie: assuming that one is object of discussion
26
delusion of control or influence
certain objects or persons have control over behaviour
27
somatic delusion
false idea about functioning of his or her body
28
nihilistic delusion
false idea that part of self, others or world is non existent
29
typical antipsychotic action
block postsynaptic DA receptor
30
atypical antipsychotic action
weak DA receptor agonist stronger antagonist of 5HT antagonist for cholinergic, histaminic and adrenergic receptors
31
c/i for typical antipsychotics
not for comatose, CNS depression, blood dyscrasias, parkinson's, narrow angle glaucoma, LV/KD/Ht insufficiency, poor controlled seizure DO, elderly with psychosis r/t NCD can prolong QT interval
32
atypical antipsychotic c/i
``` comatose severely depressed elderly with NCD related psychosis lactation QT interval prolonged cardiac arrhythmias MI hx ```
33
s/e of antipsych meds
EPS due to DA blockage prolactin elevasion anticholinergic - dry mouth, blurry, constipation, urine retention, tachycard adrenergic blockers - dizzy, ortho hypoTN, tremor, reflex tachycardia histamine - weight gain, sedation
34
magical thinking
person believes that thoughts or behaviours have control of specific situations or people.
35
type of forms of thought
``` associative looseness neologisms concrete thinking clang associations word salad circumstantial tangential mutism perseveration ```
36
associative looseness
ideas shift form one unrelated subject to another | speech may be incoherent
37
neologisms
invention of new words that a meaningless to others
38
concrete thinking
literal interpretation of environment
39
clang assocations
choice of words is governed by sounds, often rhymes
40
word salad
group of words put together randomly without logical connection
41
circumstantial
person delays in reaching point of communication due to unnecessary and tedious detail. point is met only with numerous interruptions by examiner to keep track
42
tangential
person never really gets to point of communication. unrelated topics introduced
43
mutism
inability or refulsal to speak
44
perseveration
persistently repeating the same word or idea in response to different questions
45
identification and imitation
identification occurs unconsciously imitation is conscious ego defense mechanisms used by schizo pts behaviour takes on form of that which they see in others
46
depersonalization
unstable self identity may lead to feelings of unreality | ie: seeing oneself from a distance
47
auditory hallucinations
command and non command types | rushing noises, music, clicks
48
visual hallucinations
formed and non formed images (flashes of light)
49
tactile hallucinations
something on or under the skin
50
formication
sense that something is crawling on or under the skin
51
types of affect
inappropriate bland or flat apathy
52
apathy
demonstration of indifference to or disinterest in environment
53
volition
inability to initiate goal directed activity
54
emotional ambivalence
coexistance of opposite emotions toward the same object, person or situation
55
waxy flexibility
body can be placed in bizarre or uncomfortable position, then hold that position for long periods
56
posturing
voluntary assumption of inappropriate or bizarre postures
57
anhedonia
inability to experience pleasure
58
erotomanic
higher status person loves them
59
alogia
absence of speech
60
avolition
low motivation
61
autism
withdrawn into self
62
most common s/e of antipsychotics
photosensitivity
63
1st gen a/r
``` blood dyscrasias/agranulocytosis thrombocytopenia EPS - use ABC's weight gain seizure NMS - increased CPK, tacycard, tachypnea, rigid, fever serotonin syndrome - fever, HTN, confusion, disorientation anticholinergic effects TD blunt affect prolactin elevation, amenorrhea ```