Schizophrenia Flashcards

1
Q

What are the positive symptoms of schizophrenia?

A

delusions
hallucinations
disorganized speech
grossly disorganized or catatonic motor behavior

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2
Q

What are the negative symptoms of schizophrenia?

A

avolition
social deficits
flattened affect
cognitive deficits

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3
Q

What are the different types of schizophrenic and psychotic disorders?

A

schizotypal personality disorder

delusional disorder

brief psychotic disorder

schizophreniform disorder

schizophrenia

schizoaffective disorder

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4
Q

What are the common symptoms within the spectrum of schizophrenic disorders?

A

delusions

hallucinations

disorganized speech

disorganized motor behavior or catatonia

negative symptoms

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5
Q

What is the prevalence of schizophrenia?

A

lifetime prevalence of schizophrenia 1%

schizophrenic patients may account for up to 50% of repeat hospital admissions and 25% of inpatient beds

vastly overrepresented in prison and homeless populations

estimated 1/3 of homeless in US
estimated 20% of prison population

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6
Q

What is the morbidity of schizophrenia?

A

suicidality is estimated at up to 60%: 20% attempt suicide, 5-7% die by suicide

up to 50% co-morbid with substance abuse

psychiatric co-morbidities include mood and anxiety disorders

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7
Q

What is the mortality of schizophrenia?

A

decreased life expectancy of 10-25 years

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8
Q

What are delusions?

A

fixed beliefs that are not amenable to change despite conflicting evidence

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9
Q

What are the types of delusions?

A

persecutory: belief of pursuit, harassment, or harm from an individual or group

referential: belief that gestures, comments, or cues are directed at oneself

control: belief that one’s thoughts or actions are under external influence

grandiose: belief in special abilities or status

erotomanic: belief that another has fallen in love with oneself

nihilistic: belief in impending disaster or calamity

somatic: belief in an adverse health condition

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10
Q

What are common delusions in schizophrenia?

A

though broadcasting: belief in thoughts being cast to the outside world

though insertion: belief in thoughts implanted from an outside source

thought withdrawal: belief that thoughts have been removed from mind

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11
Q

What are bizarre delusions?

A

a delusion that is neither plausible not understandable and des not derive from normal life experiences

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12
Q

What are hallucinations?

A

sensory or perceptual disturbances that are difficult or impossible to distinguish from reality

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13
Q

What are types of hallucinations?

A

auditory: occur in up to 60% of cases

tactile: tingling, burning or electrical sensations

somatic: e.g., feeling snakes writhing in one’s belly

visual: much rarer

gustatory and olfactory: tasting or smelling things that are not present

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14
Q

What are “normal” hallucinations?

A

hallucinations can occur as a normal experience

normal when falling asleep or waking (hypnogogic or hypnopompic)

induced by sensory deprivation

religious experiences and normal grieving

considered symptomatic of mental illness only when experienced in a clear sensory state

“normal” hallucinations can typically be recognized as such by the experiencer

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15
Q

What are speech and thought disturbances in schizophrenia?

A

disturbances in coherent, meaningful speech

believed to represent a though disorder

loss of connections or associations between thoughts

leads to disorganized, illogical thought patterns

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16
Q

What are examples of altered speech patterns?

A

derailment: loss of connectivity, changes of topic

tangentiality: unrelated content to conversation

word salad: lack of connection between words within a single utterance

distractibility: loss of train of thought

17
Q

What are rare and severe speech disturbances?

A

neologisms: words made up by the speaker

perseveration: persistent repetition of a word or phrase

clang associations: stringing together rhyming words

echolalia: verbatim repetitions of phrases directed at patient

blocking: inability to complete sentences due to internal distraction

18
Q

What is the disorganized/abnormal motor behavior in schizophrenia?

A

widely ranging expression

severe motor agitation

unpredictable agitation

inappropriate behavior: childlike silliness, inappropriate facial expressions, giggling

purposeless activities

catatonia

19
Q

What is catatonia in schizophrenia?

A

resistance to instruction (negativism)

lack of verbal or motor response (mutism, stupor)

excessive activity without cause (catatonic excitement)

maintaining rigid, bizarre posture

waxy flexibility (positionable catatonia)

20
Q

What is diminished social expression in schizophrenia?

A

blunting of affect
reduced facial expression
lack of eye contact
reduced intonation, gesturing

21
Q

How do schizophrenic patients retain emotional reactions?

A

different from anhedonia

patients are particularly deficient in non-verbal expression

22
Q

What is avolition in schizophrenia?

A

lack of motivation to initiate or engage in activity

apathy or indifference to consequences

23
Q

What are the attentional deficits in schizophrenia?

A

difficulty filtering irrelevant or distracting stimuli

24
Q

What are the social deficits in schizophrenia?

A

social withdrawal

decreased pleasure from social interactions

25
What are the cognitive deficits in schizophrenia?
alogogia or poverty of speech attention, long-term memory, working memory, abstraction and planning
26
What is the course and modifiers of schizophrenia?
early onset (75% of cases present before 25) no gender differences (but earlier presentation in males) 4 phases to the course of schizophrenia
27
What is the premorbid phase of schizophrenia?
preclinical and usually only described retrospectively lower performance at school: decline between 13-16 poor social adjustment: less socially responsive, less positive emotional valence delayed or abnormal motor development
28
What is the prodromal phase of schizophrenia?
marks a period of observable functional decline last months to few years typically begins in adolescence: waning social interest, irritability, depression, antagonistic thoughts and behaviors, reduced care of appearance non-specific psychiatric symptoms typically retrospectively identified as schizophrenic prodrome subtle psychotic behaviors: suspiciousness or perceptual distortions may represent the ideal therapeutic window
29
What is the florid phase of schizophrenia?
emergence of psychotic symptoms high prevalence of substance abuse may act as a precipitant: associations between alcohol, cannabis, and amphetamine use and "first break" early age of onset ad delayed treatment are associated with worse prognosis leading cause of involuntary hospitalization
30
What is the residual phase of schizophrenia?
return to behavioral state of the prodromal phase after treatment: negative symptoms: social impairment, cognitive impairments remain, remission varies among individuals residual phase typically marked by episodic psychotic illness with persistent "clinical deterioration" - failure to recover to pre-episodic level positive symptoms are typically episodic while negative symptoms are progressive 20% show favorable outcomes, recovery is rare