Schizophrenia Flashcards
Describes two positive symptoms of schizophrenia.
- Delusions: bizarre beliefs that seem real to the schizophrenic.
- Hallucinations: unreal perceptions of the environment that are auditory or visual.
Describe two negative symptoms of schizophrenia.
- Speech poverty: low level of the frequency and quality of speech.
- Avolition: reduction of interests or desires and the inability to initiate and persist in goal-directed behaviour.
What are the differences between the two classification systems?
The DSM-V has a more specific diagnostic criteria
The ICD-10 has a broader approach
Diagnosis of schizophrenia
Two or more symptoms present. Occurs between the ages 15 and 25.
What are the two classification systems?
1) The Diagnostic and Statistical Manual
2) International Classification of Disease
Outline one limitation of classification and symptoms.
High co-morbidity creates a confusing picture.
e.g. diagnosis of two disorders together like OCD and schizophrenia.
Outline another limitation of classification and systems
- African Americans more likely to diagnosed with SZ
- hearing voices linked to spirituality and ancestors in African culture.
- compared to western cultures who don’t have this belief.
- classification systems sees this as a sign of SZ.
Three factors of biological explanation
- Genetics
- Neural correlates
- Dopamine
What is meant by neural correlation
Patterns of structure or activity in the brain that occur with a schizophrenic experience.
What did Juckel et al (2006) suggest regarding abnormally low levels of activation in the ventral striatum?
Juckel et al (2006) suggested that abnormally low levels of activation in the ventral striatum, compared to healthy neurotypical controls, may be associated with the negative symptom of avolition.
Why is the ventral striatum important in this context?
The ventral striatum is associated with evaluating reward values, predictability, and risks.
How does the low activation in the ventral striatum relate to avolition?
Low levels of activation and neurotransmission in the ventral striatum may mean that individuals cannot accurately assess the reward of having enough motivation to carry out normal day-to-day tasks. As a result, they may be unable to cope with ‘normal’ life.
What is the genetic explanation
Transmission of abnormality by hereditary means.
genetic explanation for family studies
- find individuals with SZ and compare biological relatives with non-relatives to see if their similarly affected.
- Gottesman: children with two SZ parents have a concordance rate of 46%
- 1 SZ parent = 13%
- Siblings = 9%
What are monozygotic twins