Schizophrenia Flashcards
Schizophrenia
shattered disinegrated personality
not just a condition, but a syndrome
there is no cure but can be controlled by medications
PCP can cause schizophrenia
Epidemiology of schizophrenia
Lifetime prevalence of schizophrenia is 1% worldwide
there is not a difference in regards to:
- race
- socaial status
- culture
Comorbidity of Schizophrenia
- substance abuse
- nicotine dependance - Anxiety, depression, and suicide
- physical health or illness
- polydipsia
Polydipsia-
drinking massive amount of water
schizophrenics can drink so much water that they pee the bed and end up causing eletrolyte imbalances
Etiology of Schizophrenia
Biological Factors
Genetics- 65-80% is genetic
Neurobiological-
- Dopamine Theory- suggests that there is a
dopamine overload in the brain.
- Other neurochemical hypothesis
Brain Structure abnormalities-
- Usually in the frontal or temporal lobe
- Now use non-invasive PET and MRI scans
- If a family member has it, chances increase
- In Identical twins- if one has it, 50%
chance the other will have it too
- In fraternal twins, 15% chance if one has
it the other will have it too
Psycological and Environmental Factors
- Prenatal Stress- drugs, eating,
environmental
- Psychologicial Stressors- increased
cortisol
- Environmental Stressors- Sexual abuse in
children causes changes in brain
chemistry and so can toxins
-
Prodromal
Before a psycotic break
prepsychotic phase- may act weird or strange to others. My all of the sudden become withdrawn, lonely or depressed.
Phase 1 of schizophrenia
`acute phase
nervous breakdown or 1st psychotic break
this is the onset or exacerbation of symptoms
Phase 2 of schizophrenia
Stabilization phase
symptoms are diminishing, returning to a normal level of functioning
Phase 3 of schizophrenia
Maintenance phase
at or near baseline functioning
(as the disease progresses, the baseline will change with it.)
Assessment
During the prepsychotic phase- Ask them or family how they were before and after their first break
General Assessment: gain isight on Positive symptoms Negative symptoms Cognitive symptoms Affective symptoms
as well as how they are responding to medications
Positive Symptoms
Alterations in thinking Delusions Magical Thinking Paranoia Religiosity Alterations In speech Clang Associations Word Salad Neologisms Echolalia Alogia Thought insertion/deletion/blocking Alterations in perception Depersonalization Derealization Hallucination Alterations in Behavior Catatonia Echopraxia Impaired impulse control Gesturing/posturing Boundary impairment
circumstantiality
giving excessive details. More than what are needed
positive symptom
Tangentiality
frequently leaving the topic
positive symptom
Cognitive retardation
delay in responding or answering a question. Cannot finish thoughts
positive symptom
clang associations
rhyming words
positive symptom
Word Salad
jumbled speech that doesnt make sense
positive symptom
Neologisms
making up words
positive symptom
Echolalia
repeating like a parrot
positive symptom
Religiosity
preoccupied with religousness
positive symptom
What is best drug for suicide
Ssri
Haldol side effects
Muscle stiffness, tiredness
What is haldol used for
To sedate pts during acute breaks in hospital
Remember
Schizophrenia drugs make you fat except abilify
Chlorpromazine (Thorazine)
Antipsychotic : Non addictive Fast acting
Typical- 1st generation
Concrete Thinking
Alterations in thinking- positive symptom
refers to an over emphasis on specific details and impairment in the ability to use abstract concepts.
example: The nurse acts the patient what brings him to the hospital, and the patient replies “a cab” rather than explaining the reason he his seeking medical or psychiatric aid.
Nursing Intervention:
Ask the client the meaning of a proverb such as “the grass is always greener on the other side” or “people in a glass house shouldn’t throw stones”
A patient with schizophrenia might answer because the window will break.
Amitripyline (Elavil)
Antidepressant: Non Addictive - Slow Acting
Trycyclic Antidepressant